Inflammatory and genotoxic responses during 30-day welding-fume exposure period

Toxicology Letters

Volumn 154, Issue 1-2, 2004, Pages 105-115

  Yu, Il Je ^a,b   Song, Kyung Seuk ^a,b   Maeng, Seung Hee ^a   Kim, Soo Jin ^a   Sung, Jae Hyuck ^a,c   Han, Jeong Hee ^a,c   Chung, Yong Hyun ^a   Cho, Myung Haing ^c   Chung, Kyu Hyuck ^b   Han, Kuy Tae ^b   Hyun, Jin Sook ^a   Kim, Kwang Jong ^a  

^a Center for Occupational Toxicology   (South Korea)

^b Sungkyunkwan University   (South Korea)

^c Seoul National University   (South Korea)

Author keywords

Bronchoalveolar lavage; Genotoxicity; Inhalation; Lung fibrosis; Stainless steel welding fume; Welder's pneumoconiosis

Indexed keywords

ALBUMIN; INTERLEUKIN 1BETA; LACTATE DEHYDROGENASE; TUMOR NECROSIS FACTOR ALPHA;

ALBUMIN BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COMET ASSAY; CONTROLLED STUDY; DNA DAMAGE; FIBROSIS; GENOTOXICITY; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INHALATION; LACTATE DEHYDROGENASE BLOOD LEVEL; LUNG LAVAGE; NONHUMAN; PRIORITY JOURNAL; RAT; STATISTICAL SIGNIFICANCE; SUSPENDED PARTICULATE MATTER; WELDING FUME;

ACETYLGLUCOSAMINIDASE; AIR POLLUTANTS, OCCUPATIONAL; ALBUMINS; ANIMALS; BODY WEIGHT; BRONCHOALVEOLAR LAVAGE FLUID; COMET ASSAY; DNA; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; GUANINE; INHALATION EXPOSURE; L-LACTATE DEHYDROGENASE; LEUKOCYTE COUNT; LUNG; MACROPHAGES, ALVEOLAR; MALE; PULMONARY FIBROSIS; RATS; RATS, SPRAGUE-DAWLEY; SPECIFIC PATHOGEN-FREE ORGANISMS; STAINLESS STEEL; WELDING;

ANIMALIA;

EID: 4744344821     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2004.07.009     Document Type: Article

References (41)

1. ACGIH (American Conference of Governmental Industrial Hygienists) (2002). TLVs AND BEIs, Cininanati, Ohio.
2. J.M. Antonini, G.G. Krishna Murthy, R.A. Rogers, R. Albert, G.D. Ulrich, and J.D. Brain Pneumotoxicity and pulmonary clearance of different welding fumes after intratracheal instillation in the rat Toxicol. Appl. Pharmacol. 140 1996 188 199
3. J.M. Antonini, G.G. Krishna Murthy, and J.D. Brain Response to welding fumes: lung injury, inflammation and release of tumor necrosis factor alpha and interleukin 1 beta Exp. Lung Res. 23 1997 205 227
4. S. Asami, T. Hirano, R. Yamaguchi, Y. Tsurudome, H. Itoh, and H. Kasai Effects of forced and spontaneous exercise on 8-hydroxydeoxyguanosine levels in rat organs Biochem. Biophys. Res. Commun. 243 1998 678 682
5. R.S.U. Baker, A. Arlauskas, R.K. Tandon, P.T. Crisp, and J. Ellis Toxic and genotoxic action of electric arc welding fumes on cultured mammalian cells J. Appl. Toxicol. 6 1986 357 362
6. R. Bases, W.A. Franklin, T. Moy, and F. Mendez Enhanced excision repair activity in mammalian cells after ionizing radiation Int. J. Radiat. Biol. 62 1992 427 441
7. Beckett, W.S., 1996. Industries associated with respiratory diseases: welding. In: Harber, P., Schenker, M.B., Balmes, J.R. (Eds.), Occupational and Environmental Respiratory Diseases. Mosby, St. Louis, Missouri, pp. 704-717.
8. N.W. Biggart, R.R. Rinehart, and J. Verfaille Evidence for the presence of mutagenic compounds other than chromium in particles from mild steel welding Mutat. Res. 180 1987 55 65
9. U. Buerke, J. Schneider, J. Rösler, and H.J. Woitowitz Interstitial pulmonary fibrosis after severe exposure to welding fumes Am. J. Ind. Med. 41 2002 259 268
10. Carson, F., 1990. Histotechnology a Self-instruction Text, 1st ed., ASCP III, pp. 142-143.
11. H. Choi, K. Kim, S.H. Ahn, W.M. Park, S.J. Kim, Y.J. Lee, and K.C. Chung Airborne concentrations of welding fume and metals of workers exposed to welding fume Korean Ind. Hyg. Assoc. J. 9 1999 56 72
12. A.R. Collins, S.J. Duthie, and V.L. Dobson Direct enzymic detection of endogenous oxidative base damage in human lymphocyte DNA Carcinogenesis 14 9 1993 1733 1735
13. M. Foksinski, K. Bialkowski, M. Skiba, I. Ponikowska, W. Szmurlo, and R. Olinski Evaluation of 8-oxodeoxyguanosine, typical oxidative DNA damage, in lymphocytes of ozone-treated arteriosclerotic patients Mutat. Res. 438 1 1999 23 27
14. A. Funahashi, D. Schleuter, K. Pintar, E.L. Bemis, and K.A. Siegesmund Welders pneumoconiosis: tissue elemental microanalysis by energy dispersive X-ray analysis Br. J. Ind. Med. 45 1988 14 18
15. T.L. Guidotti, J.L. Abraham, P.B. DeNes, and J.B. Smith Arc welders' pneumoconiosis: application of advanced scanning electron microscopy Arch. Environ. Health 33 1978 117 124
16. K. Hansen, and R.M. Stern Welding fumes and chromium compounds in cell transformation assays J. Appl. Toxicol. 5 5 1985 306 314
17. A. Hendenstedt, D. Jesseon, B. Lidesten, C. Ramel, U. Rannug, and R.M. Stern Mutagenicity of fume particles from stainless steel welding Scand. J. Work Environ. Health 3 1977 203 211
18. M. Itoh, M. Nakamura, T. Suzuki, K. Kawai, H. Horitu, and K. Takamizawa Mechanism of chromium (VI) toxicity in Escherichia coli: is hydrogen peroxide essential in Cr (VI) toxicity J. Biochem. 117 1995 780 786
19. H. Kasai, and S. Nishimura Hydroxylation of deoxyguanosine at the C-8 position by ascorbic acid and other reducing agents Nucl. Acids Res. 12 4 1984 2137 2145
20. H. Kasai Analysis of a form of oxidative DNA damage, 8-hydroxy-2- deoxyguanosine, as a marker of cellular oxidative stress during carcinogenesis Mutat. Res. 387 1997 147 163
21. S. Kawanishi, S. Inoue, and S. Sano Mechanism of DNA cleavage induced by sodium chromate (VI) in the presence of hydrogen peroxide J. Biol. Chem. 261 13 1986 5952 5958
22. A. Kortemkamp, M. Casadevall, S.P. Faux, A. Jenner, R.O. Shayer, N. Woodbridge, and P. O'Brien A role for molecular oxygen in the formation of DNA damage during the reduction of the carcinogen chromium (VI) by gblutathione Arch. Biochem. Biophys. 329 1996 199 207
23. Y.S. Kwag, and N.S. Paik A study on airborne concentration on welding fumes and metals in confined spaces of a shipyard Korean Ind. Hyg. Assoc. J. 7 1997 107 126
24. G.M. Liss Health Effects of Welding and Cutting Fume 1985 Ontario Ministry of Labour Toronto
25. S.H. Maeng, H.W. Chung, I.J. Yu, H.Y. Kim, C.H. Lim, K.J. Kim, S.J. Kim, Y. Ootsuyama, and H. Kasai Changes of 8-OH-dG levels in DNA and its base excision repair activity in rat lungs after inhalation exposure to hexavalent chromium Mutat. Res. 539 2003 109 116
26. J. Maxild, M. Anderson, P. Kiel, and R.M. Stern Mutagenicity of fume particles from metal arc welding on stainless steel in the salmonella/microsome test Mutat. Res. 56 1978 235 243
27. Ministry of Labor Occupational Exposure Levels for Chemical Substances and Physical Agents 2002 Korean Ministry of Labor Gwacheon, Korea
28. W.K.C. Morgan, and H.D. Kerr Pathologic and physiologic studies of welders siderosis Ann. Int. Med. 58 1963 293 304
29. W.K.C. Morgan On welding, wheezing, and whimsy Am. Ind. Hyg. Assoc. J. 50 2 1989 59 69
30. NIOSH manual of analytical methods, 1999. Method No. 7300, 7604. National Institute for Occupational Health, Cincinnati.
31. P.L. Olive, and J.P. Banath Induction and rejoining of radiation-induced DNA single-strand breaks: "tail moment" as a function of position in the cell cycle Mutat. Res. 294 3 1993 275 283
32. P.L. Olive, and J.P. Banath Sizing highly fragmented DNA in individual apoptotic cells using the comet assay and a DNA cross linking agent Exp. Cell Res. 221 1 1995 19 26
33. V. Shafirovich, J. Cadet, D. Gasparutto, A. Dourandin, and N.E. Geacintov Nitrogen dioxide as an oxidizing agent of 8-oxo-7,8-dihydro-2′- deoxyguanosine but not of 2′-deoxyguanosine Chem. Res. Toxicol. 14 2 2001 233 241
34. N.P. Singh, M.T. McCoy, R.R. Tice, and E.L. Schneider A simple technique for quantitation of low levels of DNA damage in individual cells Exp. Cell Res. 175 1 1988 184 191
35. M.D. Taylor, H.R. Roberts, S.S. Leonard, X. Chi, and J.M. Antonini Effects of welding fumes of differing composition and solubility on free radical production and acute lung injury and inflammation in rats Toxicol. Sci. 75 2003 181 191
36. R.R. Tice, E. Agurell, D. Anderson, B. Burlinson, A. Hartmann, H. Kobayashi, Y. Miyamae, E. Rojas, J.C. Ryu, and Y.F. Sasaki Single cell gel/comet assay: guidelines for in vitro and in vivo genetic toxicology testing Environ. Mol. Mutagen. 35 3 2000 206 221
37. R. Yamaguchi, T. Hirano, Y. Ootsuyama, S. Asami, Y. Tsurudome, S. Fukuda, H. Yamaato, T. Tsuda, I. Tanaka, and H. Kasai Increased 8-droxyguanine in DNA and its repair activity in hamster and rat lung after intratracheal instillation of crocidolite asbestos Jpn. J. Cancer Res. 90 1999 505 509
38. A. Yarborough, Y-Y. Zhang, T-M. Hsu, and R.M. Santella Immunoperoxidase detection of 8-hydroxyguanosine in Aflatoxin B1 treated rat liver and human oral mucosal cells Cancer Res. 56 1996 683 688
39. I.J. Yu, K.J. Kim, H.K. Chang, K.S. Song, K.T. Han, J.H. Han, S.H. Maeng, Y.H. Chung, S.H. Park, K.H. Chung, J.S. Han, and H.K. Chung Pattern of deposition of stainless welding fume particle inhaled into the respiratory systems of Sprague-Dawley rats exposed to a novel welding fume generating system Toxicol. Lett. 116 2000 103 111
40. I.J. Yu, K.S. Song, H.K. Chang, J.H. Han, K.J. Kim, Y.H. Chung, S.H. Maeng, S.H. Park, K.Y. Han, K.H. Chung, and H.K. Chung Lung fibrosis in Sprague-Dawley rats, induced by exposure to manual metal arc-stainless steel welding fumes Toxicol. Sci. 63 2001 99 106
41. I.J. Yu, K.S. Song, H.K. Chang, J.H. Han, Y.H. Chung, K.T. Han, K.H. Chung, and H.K. Chung Recovery from manual metal arc-stainless steel welding-fume exposure induced lung fibrosis in Sprague-Dawley rats Toxicol. Lett. 143 2003 247 259