Cremophor EL augments the cytotoxicity of hydrogen peroxide in lymphocytes dissociated from rat thymus glands

Toxicology Letters

Volumn 154, Issue 1-2, 2004, Pages 143-148

  Iwase, Kyoko ^a   Oyama, Yasuo ^a   Tatsuishi, Tomoko ^a   Yamaguchi, Jun Ya ^a   Nishimura, Yumiko ^a   Kanada, Aimi ^a   Kobayashi, Masako ^a   Maemura, Yuko ^b   Ishida, Shiro ^b   Okano, Yoshiro ^b  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b Faculty of Pharmaceutical Sciences   (Japan)

Author keywords

Cremophor EL; Glutathione; Lymphocyte; Oxidative stress

Indexed keywords

CREMOPHOR; FLUORESCENT DYE; GLUTATHIONE; HYDROGEN PEROXIDE;

ANIMAL CELL; ARTICLE; CELL DEATH; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOPATHOGENIC EFFECT; DRUG POTENTIATION; FLOW CYTOMETRY; FLUORESCENCE ANALYSIS; INCUBATION TIME; LYMPHOCYTOTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN CONTENT; RAT; THYMOCYTE;

ANIMALS; CELL SEPARATION; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; FLOW CYTOMETRY; GLUTATHIONE; GLYCEROL; HYDROGEN PEROXIDE; LYMPHOCYTES; OXIDATIVE STRESS; RATS; RATS, WISTAR; THYMUS GLAND; VEHICLES;

EID: 4744341884     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2004.08.003     Document Type: Article

References (29)

1. O.A. Badary, O.A. Al-Shabanah, N.M. Al-Gharably, and M.M. Elmazar Effect of cremophor EL on the pharmacokinetics, antitumor activity and toxicity of doxorubicin in mice Anticancer Drugs 9 1998 809 815
2. 2+ Pharmacol. Toxicol. 71 1992 190 195
3. 2-induced changes in cell viability and cellular nonprotein thiol level of dissociated rat thymocytes Jpn. J. Pharmacol. 71 1996 299 305
4. J.H. Doroshow Role of hydrogen peroxide and hydroxyl radical formation in the killing of Ehrlich tumor cells by anticancer quinines Proc. Natl. Acad. Sci. U.S.A. 83 1986 4514 4518
5. E. Friche, P.B. Jensen, M. Schested, E.F. Demant, and N.N. Nissen The solvents cremophor EL and Tween 80 modulate daunorubicin resistance in the multidrug resistant Ehrlich ascites tumor Cancer Commun. 2 1990 297 303
6. H. Gelderblom, J. Verweij, K. Nooter, and A. Spaareboom Cremophor El: the drawbacks and advantages of vehicle selection for drug formulation Eur. J. Cancer 37 2001 1590 1598
7. S. Hirama, T. Tatsuishi, K. Iwase, H. Nakao, C. Umebayashi, Y. Nishizaki, M. Kobayashi, S. Ishida, Y. Okano, and Y. Oyama Flow-cytometric analysis on adverse effects of polysorbate 80 in rat thymocytes Toxicology 199 2004 137 143
8. A. Jelinek, and H.P. Klocking In vitro toxicity of surfactants in U937 cells: cell membrane integrity and mitochondrial function Exp. Toxicol. Pathol. 50 1998 472 476
9. P. Kovacic, and J.A. Osuna Mechanisms of anti-cancer agents: emphasis on oxidative stress and electron transfer Curr. Pharm. Des. 6 2000 277 309
10. A. Meister, and M.E. Anderson Glutathione Ann. Rev. Biochem. 52 1983 711 760
11. M.J. Millward, L.K. Webster, D. Rischin, K.H. Stokes, G.C. Toner, J.F. Bishop, I.N. Olver, B.M. Linnahan, M.E. Linsenmeyer, and D.M. Woodcock Phase I trial of cremophor EL with bolus doxorubicin Clin. Cancer Res. 4 1998 2321 2329
12. H. Mizutani, S. Tada-Oikawa, Y. Hiraku, S. Oikawa, M. Kojima, and S. Kawanishi Mechanism of apoptosis induced by a new topoisomerase inhibitor through the generation of hydrogen peroxide J. Biol. Chem. 277 2002 30684 30689
13. M. Nakata, Y. Oyama, L. Chikahisa, Y. Yamazaki, and M. Satoh Flow cytometric analysis on tri-n-butyltin-induced increase in annexin V binding to membranes of rat thymocytes Environ. Toxicol. Pharmacol. 7 1999 267 273
14. 2 Jpn. J. Pharmacol. 75 1997 363 370
15. R.L. Oberle, T.J. Moore, and D.A. Krummel Evaluation of mucosal damage of surfactants in rat jejunum and colon J. Pharmacol. Toxicol. Methods 33 1995 75 81
16. 2+ of mouse thymocytes: comparison with the action of A23187 Jpn. J. Pharmacol. 60 1992 159 167
17. Y. Oyama, S. Noguchi, M. Nakata, Y. Okada, Y. Yamazaki, M. Funai, L. Chikahisa, and K. Kanemaru Exposure of rat thymocytes to hydrogen peroxide increases annexin V binding to membranes: inhibitory action of deferoxamine and quercetin Eur. J. Pharmacol. 384 1999 47 52
18. D. Rischin, L.K. Webster, M.J. Millward, B.M. Linahan, G.C. Toner, A.M. Woolett, C.G. Morton, and J.F. Bishop Cremophor pharmacokinetics in patients receiving 3-, 6-, and 24-hour infusions of paclitaxel J. Natl. Cancer Inst. 88 1996 1297 1301
19. T. Shimomura, H. Fujiwara, S. Ikawa, J. Kigawa, and N. Terakawa Effects of taxol on blood cells Lancet 352 1998 541 542
20. G.J. Schuurhuis, H.J. Broxterman, H.M. Pinedo, T.H. van Heijningen, C.K. van Kaken, J.B. Vermorken, E.C. Spoelstra, and J. Lankeima The polyethylene castor oil cremophor EL modifies multidrug resistance Br. J. Cancer 62 1990 591 594
21. S. Simizu, M. Takada, K. Umezawa, and M. Imoto Requirement of caspase-3(-like) protease-mediated hydrogen peroxide production for apoptosis induced by various anticancer drugs J. Biol. Chem. 273 1998 26900 26907
22. J. Szebeni, F.M. Muggia, and C.R. Alving Complement activation by cremophor EL as a possible contributor to hypersensitivity to paclitaxel: an in vitro study J. Natl. Cancer Inst. 90 1998 300 306
23. Tatsuishi, T., Oyama, Y., Iwase, K., Yamaguchi, J., Kobayashi, M., Nishimura, Y., Kanada, A., Hirama, H., 2004. Polysorbate 80 increases the susceptibility to oxidative stress in rat thymocytes. Toxicology 199, 137-143.
24. I. Tsujino, T. Yamazaki, M. Masutani, U. Sawada, and T. Horie Effect of Tween-80 on cell killing by etoposide in human lung adenocarcinoma cells Cancer Chemother. Pharmacol. 43 1999 29 34
25. I. Vermes, C. Haanen, H. Steffens-Nakken, and C. Reutelingsperger A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotoic cells using fluorescent labeled Annexin V J. Immunol. Methods 184 1995 39 51
26. J. Watkins, A.M. Ward, and T.N. Appleyard Adverse reactions to intravenous anaesthetic induction agents Br. Med. J. 2 1997 1084 1085
27. A.J. Windebank, M.D. Blexrud, and P.C. Groen Potential neurotoxicity of the solvent vehicle for cyclosporine J. Pharmacol. Exp. Ther. 268 1994 1051 1056
28. D.M. Woodcock, S. Jefferson, M.E. Linsenmeyer, D.J. Crowther, G.M. Chojnowski, B. Williams, and I. Bertoncello Reversal of multidrug resistance with Cremophor EL, a common vehicle for water-insoluble vitamins and drugs Cancer Res. 50 1990 4199 4203
29. T. Zordan-Nudo, V. Ling, Z. Liu, and S. Georges Effects of nonionic detergents on P-glycoprotein drug binding and reversal of multidrug resistance Cancer Res. 53 1993 897 902