Lipid cubic phases in topical drug delivery: Visualization of skin distribution using two-photon microscopy

Journal of Controlled Release

Volumn 129, Issue 3, 2008, Pages 163-169

  Bender, Johanna ^a   Simonsson, Carl ^b   Smedh, Maria ^c   Engström, Sven ^a   Ericson, Marica B ^b,d  

^a CHALMERS UNIVERSITY OF TECHNOLOGY   (Sweden)

^b UNIVERSITY OF GOTHENBURG   (Sweden)

^c UNIVERSITY OF GOTHENBURG   (Sweden)

^d SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Bicontinuous cubic phase; Human skin; Micro fissures; Monoolein; Passive diffusion; Phytantriol; Sulphorhodamine B; Two photon microscopy

Indexed keywords

CHEMOTHERAPY; CONTROLLED DRUG DELIVERY; DRUG DELIVERY; DRUG DOSAGE; FLUORESCENCE; HYDROPHILICITY; LASERS; LIGHT EMISSION; LIPIDS; LUMINESCENCE; MATRIX ALGEBRA; PHOTONS; PULSED LASER APPLICATIONS; PULSED LASER DEPOSITION; SKIN; TITANIUM;

APPLIED (CO); BICONTINUOUS CUBIC PHASES; CELL NUCLEUS; CUBIC PHASES; CUBIC SYSTEMS; DELIVERY VEHICLES; ELSEVIER (CO); FEMTO SECONDS; HUMAN SKIN; HYDROPHILIC COMPOUNDS; HYDROPHILIC MODEL; KERATINOCYTES (KC); LASER SCANNING; LIPID MATRICES; MONOOLEIN (MO); OPTICAL SECTIONING; PASSIVE DIFFUSION (PD); PHYTANTRIOL; SAPPHIRE LASERS; STRATUM GRANULOSUM (SG); SUSTAINED RELEASE (SR); TOPICAL DELIVERY; TWO-PHOTON MICROSCOPY (TPM);

STRAIN RELAXATION;

DRUG VEHICLE; GLYCEROL OLEATE; PHYTANTRIOL; RHODAMINE; SULPHORHODAMINE B; WATER;

ARTICLE; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG PENETRATION; FEMALE; FLUORESCENCE MICROSCOPY; HUMAN; KERATINOCYTE; PRIORITY JOURNAL;

ADMINISTRATION, CUTANEOUS; DIFFUSION; DRUG DELIVERY SYSTEMS; FATTY ALCOHOLS; FLUORESCENT DYES; GLYCERIDES; HUMANS; KERATINOCYTES; LIPIDS; MICROSCOPY, FLUORESCENCE, MULTIPHOTON; MOLECULAR STRUCTURE; REFERENCE STANDARDS; RHODAMINES; SKIN; SKIN ABSORPTION; WATER;

EID: 47349107425     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2008.04.020     Document Type: Article

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