Erythroid expansion and survival in response to acute anemia stress: The role of EPO receptor, GATA-1, Bcl-xL and caspase-3

Cell Biology International

Volumn 32, Issue 8, 2008, Pages 966-978

  Aispuru, Gualberto Rodrigo ^a   Aguirre, María Victoria ^a   Aquino Esperanza, José Andrés ^a   Lettieri, Carolina Noelia ^a   Juaristi, Julián Antonio ^a   Brandan, Nora Cristina ^a,b  

^a UNIVERSIDAD NACIONAL DEL NORDESTE   (Argentina)

^b Facultad de Ciencias Naturales e Instituto M Lillo   (Argentina)

Author keywords

Bcl xL; Caspase 3; Erythropoietic stress; Erythropoietin receptor; GATA 1

Indexed keywords

CASPASE 3; ERYTHROPOIETIN RECEPTOR; FLUOROURACIL; PROTEIN BAX; PROTEIN BCL XL; TRANSCRIPTION FACTOR GATA 1;

ACUTE STRESS; ANEMIA; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BONE MARROW CELL; CELL CULTURE; CELL DIFFERENTIATION; CELL DISRUPTION; CELL EXPANSION; CELL FUNCTION; CELL PROLIFERATION; CELL SIZE; CELL SURVIVAL; CONTROLLED STUDY; CYTOARCHITECTURE; DNA DETERMINATION; ENZYME ACTIVITY; ERYTHROCYTE; ERYTHROID CELL; FEMALE; GENE OVEREXPRESSION; MITOSIS INDEX; MOUSE; NICK END LABELING; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; SCANNING ELECTRON MICROSCOPY; WESTERN BLOTTING;

ACUTE DISEASE; ANEMIA; ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BCL-X PROTEIN; BONE MARROW CELLS; CASPASE 3; CELL PROLIFERATION; ERYTHROID PROGENITOR CELLS; ERYTHROPOIESIS; FEMALE; FLUOROURACIL; GATA1 TRANSCRIPTION FACTOR; MICE; MITOTIC INDEX; RECEPTORS, ERYTHROPOIETIN;

MUS;

EID: 47349093592     PISSN: 10656995     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cellbi.2008.04.014     Document Type: Article

References (57)

1. Adams J.M., and Cory S. The Bcl-2 protein family: arbiters of cell survival. Science 281 (1998) 1322-1326
2. Aguirre M.V., Juaristi J.A., Alvarez M.A., and Brandan N.C. Characteristics of in vivo murine erythropoietic response to sodium orthovanadate. Chem Biol Interact 156 (2005) 55-68
3. Bauer A., Tronche F., Wessely O., Kellendonk C., Reichardt H.M., Steinlein P., et al. The glucocorticoid receptor is required for stress erythropoiesis. Genes Dev 13 (1999) 2996-3002
4. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72 (1976) 248-254
5. 3H-thymidine into DNA. Br J Haematol 47 (1981) 469-478
6. Broudy V.C., Lin N., Brice M., Nakamoto B., and Papayannopoulou T. Erythropoietin receptor characteristics on primary human erythroid cells. Blood 77 (1991) 2583-2590
7. Broudy V.C., Lin N.L., Priestley G.V., Nocka K., and Wolf N.S. Interaction of stem cell factor and its receptor c-kit mediates lodgment and acute expansion of hematopoietic cells in the murine spleen. Blood 88 (1996) 75-81
8. Budihardjo I., Oliver H., Lutter M., Luo X., and Wang X. Biochemical pathways of caspase activation during apoptosis. Annu Rev Cell Dev Biol 15 (1999) 269-290
9. Carlile G.W., Smith D.H., and Wiedmann M. Caspase-3 has a nonapoptotic function in erythroid maturation. Blood 103 (2004) 4310-4316
10. Dai C., and Krantz S.B. Interferon gamma induces up regulation and activation of caspases 1, 3 and 8 to produce apoptosis in human erythroid progenitor cells. Blood 93 (1999) 3309-3316
11. De Maria R., Zeuner A., Eramo A., Domenichelli C., Bonci D., Grignani F., et al. Negative regulation of erythropoiesis by caspase-mediated cleavage of GATA-1. Nature 401 (1999) 489-493
12. Dolzing H., Boulmé F., Stangl K., Deiner E.M., Mikulits W., Beug H., et al. Establishment of normal, terminally differentiating mouse erythroid progenitors: molecular characterization by cDNA arrays. Faseb J 15 (2001) 1442-1444
13. Ebert B.L., and Bunn H.F. Regulation of the erythropoietin gene. Blood 94 (1999) 1864-1877
14. Erslev A.J., and Beutler E. Production and destruction of erythrocytes. In: Beutler E., Lichtman M.A., Coller B.S., and Kipps I.J. (Eds). Williams hematology (1995), McGraw-Hill Inc, New York 425-441
15. Fadeel B., Orrenius S., and Zhivotovsky B. The most unkindest cut of all: on the multiple roles of mammalian caspases. Leukemia 14 (2000) 1514-1525
16. Forsberg E.C., Bhattacharya D., and Weissman I.L. Hematopoietic stem cells: expression profiling and beyond. Stem Cell Rev 2 (2006) 23-30
17. Gavrieli Y., Sherman Y., and Ben-Sasson S.A. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 119 (1992) 493-501
18. Gregoli P.A., and Boundurant M.C. The roles of Bcl-X(L) and apopain in the control of erythropoiesis by erythropoietin. Blood 90 (1997) 630-640
19. Gregory C.J., Tepperman A.D., McCulloch E.A., and Till J.E. Erythropoietic progenitors capable of colony formation in culture: response of normal and genetically anemic W-W-V mice to manipulations of the erythron. J Cell Physiol 84 (1974) 1-12
20. L expression. Blood 94 (1999) 87-96
21. Hara H., and Ogawa M. Erythropoietic precursors in mice with phenylhydrazine-induced anemia. Am J Hematol 1 (1976) 45-58
22. Jelkmann W. Molecular biology of erythropoietin. Intern Med 43 (2004) 649-659
23. Juaristi J.A., Aguirre M.V., Carmuega R.J., Romero-Benítez M., Alvarez M.A., and Brandan N.C. Hematotoxicity induced by paclitaxel: in vitro and in vivo assays during normal murine hematopoietic recovery. Methods Find Exp Clin Pharmacol 23 (2001) 161-167
24. L expressions in murine erythropoiesis after cyclophosphamide treatment. Toxicology 231 (2007) 188-199
25. Koury M.J., and Boundurant M.C. Control of red cell production: the roles of programmed cell death (apoptosis) and erythropoietin. Transfusion 30 (1990) 673-674
26. Koury M.J., Sawyer S.T., and Boundurant M.C. Splenic erythroblasts in anemia-inducing Friend disease: a source of cells for studies of erythropoietin-mediated differentiation. J Cell Physiol 121 (1984) 526-532
27. Krauss S.W., Lo A.J., Short S.A., Koury M.J., Monadas N., and Chasis J.A. Nuclear substructure reorganization during late-stage erythropoiesis is selective and does not involve caspase cleavage of major nuclear substructural proteins. Blood 106 (2005) 2200-2205
28. Lenox L.E., Perry J.M., and Paulson R.F. BMP4 and Madh5 regulate the erythroid response to acute anemia. Blood 105 (2005) 2741-2748
29. Li K., Menon M.P., Karur V.G., Hegde S., and Wojchowski D.M. Attenuated signaling by a phosphotyrosine-null EPO receptor form in primary erythroid progenitor cells. Blood 102 (2003) 3147-3153
30. Lin C.S., Lim S.K., D'Agati V., and Costantini F. Differential effects of an erythropoietin receptor gene disruption on primitive and definitive erythropoiesis. Genes Dev 10 (1996) 154-164
31. Miyamoto T., Iwasaki H., Reizis B., Ye M., Graf T., Weissman I.L., et al. Myeloid or lymphoid promiscuity as a critical step in hematopoietic lineage commitment. Dev Cell 1 (2002) 137-147
32. Morrison S.J., Prowse K.R., Ho P., and Weissman I.L. Telomerase activity in hematopoietic cells is associated with self-renewal potential. Immunity 5 (1996) 207-216
33. Motoyama N., Kimura T., Takahashi T., Watanabe T., and Nakano T. Bcl-x prevents apoptotic cell death of both primitive and definitive erythrocytes at the end of maturation. J Exp Med 189 (1999) 1691-1698
34. Ou L.C., Kim D., Layton Jr. W.M., and Smith R.P. Splenic erythropoiesis in polycythemic response of the rat to high-altitude exposure. J Appl Physiol 48 (1980) 857-861
35. Perry C., and Soreq H. Transcriptional regulation of erythropoiesis. Fine tuning of combinatorial multi-domain elements. Eur J Biochem 269 (2002) 3607-3618
36. Peschle C., Magli M.C., Cillo C., Lettieri F., Genovese A., Pizzella F., et al. Kinetics of erythroid and myeloid stem cells in post-hypoxia polycythaemia. Br J Haematol 37 (1977) 345-352
37. Podesta F., Romeo G., Liu W.H., Krajewski S., Reed J.C., Gerhardinger C., et al. Bax is increased in the retina of diabetic subjects and is associated with pericyte apoptosis in vivo and in vitro. Am J Pathol 156 (2000) 1025-1032
38. Randall T.D., and Weissman I.L. Phenotypic and functional changes induced at the clonal level in hematopoietic stem cells after 5-fluorouracil treatment. Blood 15 (1997) 3596-3606
39. Reissmann K.R., and Samorapoompichit S. Effect of erythropoietin on early recovery of erythropoiesis in mice after sublethal dose of 5-fluorouracil. Proc Soc Exp Biol Med 128 (1968) 898-901
40. Ribeil J.A., Zermati Y., Vandekerckhove J., Dussiot M., Kersual J., and Hermine O. Erythropoiesis: a paradigm for the role of caspases in cell death and differentiation. J Soc Biol 199 (2005) 219-231
41. Rich I.N. The effect of 5-fluorouracil on erythropoiesis. Blood 15 (1991) 1164-1170
42. Romero-Benitez M.M., Aguirre M.V., Juaristi J.A., Alvarez M.A., Trifaro J.M., and Brandan N.C. In vivo erythroid recovery following paclitaxel injury: correlation between GATA-1, c-MYB, NF-E2, EPO receptor expressions, and apoptosis. Toxicol Appl Pharmacol 194 (2004) 230-238
43. L and Bcl-2. Blood 1 (1999) 1576-1582
44. Socolovsky M. Molecular insights into stress erythropoiesis. Curr Opin Hematol 14 (2007) 215-224
45. Socolovsky M., Fallon A.E., Wang S., Brugnara C., and Lodish H.F. Fetal anemia and apoptosis of red cell progenitors in Stat5a-/-5b-/- mice: a direct role for Stat5 in Bcl-X(L) induction. Cell 23 (1999) 181-191
46. Socolovsky M., Nam H., Fleming M.D., Haase V.H., Brugnara C., and Lodish H.F. Ineffective erythropoiesis in Stat5a (-/-) 5b (-/-) mice due to decreased survival of early erythroblasts. Blood 98 (2001) 3261-3273
47. Takatsuki F., Miyasaka Y., Kikuchi T., Suzuki M., and Mauro J. Improvement of erythroid toxicity by lentinan and erythropoietin in mice treated with chemotherapeutic agents. Exp Hematol 24 (1996) 416-422
48. Vannucchi A.M., Bianchi L., Cellar C., Paoletti F., Carrai V., Calzolari A., et al. Accentuated response to phenylhydrazine and erythropoietin in mice genetically impaired for their GATA-1 expression (GATA-1(low) mice). Blood 15 (2001) 3040-3050
49. Wei M.C., Zong W.X., Cheng E.H., Lindsten T., Panoutsakopoulou V., Ross A.J., et al. Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death. Science 27 (2001) 727-730
50. Weiss M.J., and Orkin S.H. Transcription factor GATA-1 permits survival and maturation of erythroid precursors by preventing apoptosis. Proc Natl Acad Sci USA 10 (1995) 9623-9627
51. Welch J.J., Watts J.A., Vakoc C.R., Yao Y., Wang H., Hardison R.C., et al. Global regulation of erythroid gene expression by transcription factor GATA-1. Blood 15 (2004) 3136-3147
52. Wen D., Boissel J.P., Tracy T.E., Gruninger R.H., Mulcahy L.S., Czelusniak J., et al. Erythropoietin structure-function relationships: high degree of sequence homology among mammals. Blood 82 (1993) 1507-1516
53. Wickrema A., Bondurant M.C., and Krantz S.B. Abundance and stability of erythropoietin receptor mRNA in mouse erythroid progenitor cells. Blood 1 (1991) 2269-2275
54. Wu H., Liu X., Jaenisch R., and Lodish H.F. Generation of committed erythroid BFU-E and CFU-E progenitors does not require erythropoietin or the erythropoietin receptor. Cell 6 (1995) 59-67
55. Zermati Y., Garrido C., Amsellem S., Fishelson S., Bouscary D., Valensi F., et al. Caspase activation is required for terminal erythroid differentiation. J Exp Med 193 (2001) 247-254
56. Zhang L., Yu J., Park B.H., Kinzler K.W., and Vogelstein B. Role of BAX in the apoptotic response to anticancer agents. Science 290 (2000) 989-992
57. Zheng J., Kitajima K., Sakai E., Kimura T., Minegishi N., Yamamoto M., et al. Differential effects of GATA-1 on proliferation and differentiation of erythroid lineage cells. Blood 107 (2006) 520-527