How cytokines can influence the brain: A role for chemokines?

Journal of Neuroimmunology

Volumn 198, Issue 1-2, 2008, Pages 46-55

  Guyon, Alice ^a   Massa, Fabienne ^a   Rovère, Carole ^a   Nahon, Jean Louis ^a  

^a CNRS   (France)

Author keywords

Chemokines; Cytokines; Hormones; Hypothalamus; Inflammation; LPS; Neurons; Vagus nerve

Indexed keywords

CYTOKINE; LEPTIN; STROMAL CELL DERIVED FACTOR 1; STROMAL CELL DERIVED FACTOR 1ALPHA;

BRAIN; BRAIN NERVE CELL; HORMONE DETERMINATION; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; REVIEW; VAGUS NERVE;

AFFERENT PATHWAYS; ANIMALS; BRAIN; CHEMOKINES; CYTOKINES; HORMONES; HUMANS; MODELS, BIOLOGICAL; NEURONS, AFFERENT;

EID: 47249163646     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2008.04.009     Document Type: Review

References (94)

1. Abbadie C., Lindia J.A., Cumiskey A.M., Peterson L.B., Mudgett J.S., Bayne E.K., DeMartino J.A., MacIntyre D.E., and Forrest M.J. Impaired neuropathic pain responses in mice lacking the chemokine receptor CCR2. Proc. Natl. Acad. Sci. U. S. A. 100 (2003) 7947-7952
2. Bacon K.B., and Harrison J.K. Chemokines and their receptors in neurobiology: perspectives in physiology and homeostasis. J. Neuroimmunol. 104 (2000) 92-97
3. Bajetto A., Bonavia R., Barbero S., Florio T., and Schettini G. Chemokines and their receptors in the central nervous system. Front Neuroendocrinol. 22 (2001) 147-184
4. Balabanian K., Lagane B., Infantino S., Chow K.Y., Harriague J., Moepps B., Arenzana-Seisdedos F., Thelen M., and Bachelerie F. The chemokine SDF-1/CXCL12 binds to and signals through the orphan receptor RDC1 in T lymphocytes. J. Biol. Chem. 280 (2005) 35760-35766
5. Banisadr G., Fontanges P., Haour F., Kitabgi P., Rostene W., and Melik Parsadaniantz S. Neuroanatomical distribution of CXCR4 in adult rat brain and its localization in cholinergic and dopaminergic neurons. Eur. J. Neurosci. 16 (2002) 1661-1671
6. Banisadr G., Skrzydelski D., Kitabgi P., Rostene W., and Parsadaniantz S.M. Highly regionalized distribution of stromal cell-derived factor-1/CXCL12 in adult rat brain: constitutive expression in cholinergic, dopaminergic and vasopressinergic neurons. Eur. J. Neurosci. 18 (2003) 1593-1606
7. Basa N.R., Wang L., Arteaga J.R., Heber D., Livingston E.H., and Tache Y. Bacterial lipopolysaccharide shifts fasted plasma ghrelin to postprandial levels in rats. Neurosci. Lett. 343 (2003) 25-28
8. Bezzi P., Gundersen V., Galbete J.L., Seifert G., Steinhauser C., Pilati E., and Volterra A. Astrocytes contain a vesicular compartment that is competent for regulated exocytosis of glutamate. Nat. Neurosci. 7 (2004) 613-620
9. Bindslev N. A homotropic two-state model and auto-antagonism. BMC Pharmacol. 4 (2004) 11
10. Block M.L., and Hong J.S. Microglia and inflammation-mediated neurodegeneration: multiple triggers with a common mechanism. Prog. Neurobiol. 76 (2005) 77-98
11. Bonavia R., Bajetto A., Barbero S., Pirani P., Florio T., and Schettini G. Chemokines and their receptors in the CNS: expression of CXCL12/SDF-1 and CXCR4 and their role in astrocyte proliferation. Toxicol. Lett. 139 (2003) 181-189
12. Burdyga G., Varro A., Dimaline R., Thompson D.G., and Dockray G.J. Feeding-dependent depression of melanin-concentrating hormone and melanin-concentrating hormone receptor-1 expression in vagal afferent neurones. Neuroscience 137 (2006) 1405-1415
13. Cartier L., Hartley O., Dubois-Dauphin M., and Krause K.H. Chemokine receptors in the central nervous system: role in brain inflammation and neurodegenerative diseases. Brain Res. Brain Res. Rev. 48 (2005) 16-42
14. Crump M.P., Gong J.H., Loetscher P., Rajarathnam K., Amara A., Arenzana-Seisdedos F., Virelizier J.L., Baggiolini M., Sykes B.D., and Clark-Lewis I. Solution structure and basis for functional activity of stromal cell-derived factor-1; dissociation of CXCR4 activation from binding and inhibition of HIV-1. EMBO J. 16 (1997) 6996-7007
15. Dantzer R., and Kelley K.W. Twenty years of research on cytokine-induced sickness behavior. Brain Behav. Immun. 21 (2007) 153-160
16. Delgado M.B., Clark-Lewis I., Loetscher P., Langen H., Thelen M., Baggiolini M., and Wolf M. Rapid inactivation of stromal cell-derived factor-1 by cathepsin G associated with lymphocytes. Eur. J. Immunol. 31 (2001) 699-707
17. Eggermann E., Bayer L., Serafin M., Saint-Mleux B., Bernheim L., Machard D., Jones B.E., and Muhlethaler M. The wake-promoting hypocretin-orexin neurons are in an intrinsic state of membrane depolarization. J. Neurosci. 23 (2003) 1557-1562
18. Ferri C.C., and Ferguson A.V. Interleukin-1 beta depolarizes paraventricular nucleus parvocellular neurones. J. Neuroendocrinol. 15 (2003) 126-133
19. Ferri C.C., Yuill E.A., and Ferguson A.V. Interleukin-1beta depolarizes magnocellular neurons in the paraventricular nucleus of the hypothalamus through prostaglandin-mediated activation of a non selective cationic conductance. Regul. Pept. 129 (2005) 63-71
20. Fujiwara M., Ohgami Y., Inada K., and Iwasaki K. Effect of active fragments of arginine-vasopressin on the disturbance of spatial cognition in rats. Behav. Brain Res. 83 (1997) 91-96
21. Furukawa K., and Mattson M.P. The transcription factor NF-kappaB mediates increases in calcium currents and decreases in NMDA- and AMPA/kainate-induced currents induced by tumor necrosis factor-alpha in hippocampal neurons. J. Neurochem. 70 (1998) 1876-1886
22. Gerashchenko D., and Shiromani P.J. Effects of inflammation produced by chronic lipopolysaccharide administration on the survival of hypocretin neurons and sleep. Brain Res. 1019 (2004) 162-169
23. Gosselin R.D., Varela C., Banisadr G., Mechighel P., Rostene W., Kitabgi P., and Melik-Parsadaniantz S. Constitutive expression of CCR2 chemokine receptor and inhibition by MCP-1/CCL2 of GABA-induced currents in spinal cord neurones. J. Neurochem. 95 (2005) 1023-1035
24. Guyon A., and Nahon J.L. Multiple actions of the chemokine stromal cell-derived factor-1alpha on neuronal activity. J. Mol. Endocrinol. 38 (2007) 365-376
25. Guyon A., Banisadr G., Rovere C., Cervantes A., Kitabgi P., Melik-Parsadaniantz S., and Nahon J.L. Complex effects of stromal cell-derived factor-1alpha on melanin-concentrating hormone neuron excitability. Eur. J. Neurosci. 21 (2005) 701-710
26. Guyon A., Rovere C., Cervantes A., Allaeys I., and Nahon J.L. Stromal cell-derived factor-1alpha directly modulates voltage-dependent currents of the action potential in mammalian neuronal cells. J. Neurochem. 93 (2005) 963-973
27. Guyon A., Skrzydelsi D., Rovere C., Rostene W., Parsadaniantz S.M., and Nahon J.L. Stromal cell-derived factor-1alpha modulation of the excitability of rat substantia nigra dopaminergic neurones: presynaptic mechanisms. J. Neurochem. 96 (2006) 1540-1550
28. Hayes M.R., and Covasa M. CCK and 5-HT act synergistically to suppress food intake through simultaneous activation of CCK-1 and 5-HT3 receptors. Peptides 26 (2005) 2322-2330
29. Hermann G.E., Tovar C.A., and Rogers R.C. LPS-induced suppression of gastric motility relieved by TNFR:Fc construct in dorsal vagal complex. Am. J. Physiol. Gastrointest. Liver Physiol. 283 (2002) G634-G639
30. Hirono M., Yoshioka T., and Konishi S. GABA(B) receptor activation enhances mGluR-mediated responses at cerebellar excitatory synapses. Nat. Neurosci. 4 (2001) 1207-1216
31. Hosoi T., Okuma Y., Matsuda T., and Nomura Y. Novel pathway for LPS-induced afferent vagus nerve activation: possible role of nodose ganglion. Auton. Neurosci. 120 (2005) 104-107
32. Houzen H., Kikuchi S., Kanno M., Shinpo K., and Tashiro K. Tumor necrosis factor enhancement of transient outward potassium currents in cultured rat cortical neurons. J. Neurosci. Res. 50 (1997) 990-999
33. Huising M.O., Stet R.J., Kruiswijk C.P., Savelkoul H.F., and Lidy Verburg-van Kemenade B.M. Molecular evolution of CXC chemokines: extant CXC chemokines originate from the CNS. Trends Immunol. 24 (2003) 307-313
34. John G.R., Lee S.C., and Brosnan C.F. Cytokines: powerful regulators of glial cell activation. Neuroscientist 9 (2003) 10-22
35. Johnson R.W. Immune and endocrine regulation of food intake in sick animals. Domest. Anim. Endocrinol. 15 (1998) 309-319
36. Jourdain P., Bergersen L.H., Bhaukaurally K., Bezzi P., Santello M., Domercq M., Matute C., Tonello F., Gundersen V., and Volterra A. Glutamate exocytosis from astrocytes controls synaptic strength. Nat. Neurosci. 10 (2007) 331-339
37. Katafuchi T., Motomura K., Baba S., Ota K., and Hori T. Differential effects of tumor necrosis factor-alpha and -beta on rat ventromedial hypothalamic neurons in vitro. Am. J. Physiol. 272 (1997) R1966-R1971
38. Kim C.H. Chemokine-chemokine receptor network in immune cell trafficking. Curr. Drug Targets Immune Endocr. Metabol. Disord. 4 (2004) 343-361
39. Kim Y.W., Kim K.H., Ahn D.K., Kim H.S., Kim J.Y., Lee D.C., and Park S.Y. Time-course changes of hormones and cytokines by lipopolysaccharide and its relation with anorexia. J. Physiol. Sci. 57 (2007) 159-165
40. Konsman J.P., Parnet P., and Dantzer R. Cytokine-induced sickness behaviour: mechanisms and implications. Trends Neurosci. 25 (2002) 154-159
41. Kremlev S.G., Roberts R.L., and Palmer C. Differential expression of chemokines and chemokine receptors during microglial activation and inhibition. J. Neuroimmunol. 149 (2004) 1-9
42. Lee Y.B., Nagai A., and Kim S.U. Cytokines, chemokines, and cytokine receptors in human microglia. J. Neurosci. Res. 69 (2002) 94-103
43. Lu S.C., Shieh W.Y., Chen C.Y., Hsu S.C., and Chen H.L. Lipopolysaccharide increases resistin gene expression in vivo and in vitro. FEBS Lett. 530 (2002) 158-162
44. Luo Y., Cai J., Xue H., Mattson M.P., and Rao M.S. SDF1alpha/CXCR4 signaling stimulates beta-catenin transcriptional activity in rat neural progenitors. Neurosci. Lett. 398 (2006) 291-295
45. Luster A.D. Chemokines-chemotactic cytokines that mediate inflammation. N. Engl. J. Med. 338 (1998) 436-445
46. Luther S.A., and Cyster J.G. Chemokines as regulators of T cell differentiation. Nat. Immunol. 2 (2001) 102-107
47. Ma Q.P., and Woolf C.J. Progressive tactile hypersensitivity: an inflammation-induced incremental increase in the excitability of the spinal cord. Pain 67 (1996) 97-106
48. MacDougald O.A., and Burant C.F. The rapidly expanding family of adipokines. Cell Metab. 6 (2007) 159-161
49. Mariotto S., Suzuki Y., Persichini T., Colasanti M., Suzuki H., and Cantoni O. Cross-talk between NO and arachidonic acid in inflammation. Curr. Med. Chem. 14 (2007) 1940-1944
50. McGeer P.L., and McGeer E.G. Inflammation and the degenerative diseases of aging. Ann. N. Y. Acad. Sci. 1035 (2004) 104-116
51. Mellado M., Rodriguez-Frade J.M., Vila-Coro A.J., Fernandez S., Martin de Ana A., Jones D.R., Toran J.L., and Martinez A.C. Chemokine receptor homo- or heterodimerization activates distinct signaling pathways. EMBO J. 20 (2001) 2497-2507
52. Mentlein R. Dipeptidyl-peptidase IV (CD26)-role in the inactivation of regulatory peptides. Regul. Pept. 85 (1999) 9-24
53. Meucci O., Fatatis A., Simen A.A., Bushell T.J., Gray P.W., and Miller R.J. Chemokines regulate hippocampal neuronal signaling and gp120 neurotoxicity. Proc. Natl. Acad. Sci. U. S. A. 95 (1998) 14500-14505
54. Monzillo L.U., Hamdy O., Horton E.S., Ledbury S., Mullooly C., Jarema C., Porter S., Ovalle K., Moussa A., and Mantzoros C.S. Effect of lifestyle modification on adipokine levels in obese subjects with insulin resistance. Obes. Res. 11 (2003) 1048-1054
55. Murphy P.M., Baggiolini M., Charo I.F., Hebert C.A., Horuk R., Matsushima K., Miller L.H., Oppenheim J.J., and Power C.A. International union of pharmacology. XXII. Nomenclature for chemokine receptors. Pharmacol Rev. 52 (2000) 145-176
56. Oh S.B., Endoh T., Simen A.A., Ren D., and Miller R.J. Regulation of calcium currents by chemokines and their receptors. J. Neuroimmunol. 123 (2002) 66-75
57. Ohtani Y., Minami M., Kawaguchi N., Nishiyori A., Yamamoto J., Takami S., and Satoh M. Expression of stromal cell-derived factor-1 and CXCR4 chemokine receptor mRNAs in cultured rat glial and neuronal cells. Neurosci. Lett. 249 (1998) 163-166
58. Percherancier Y., Berchiche Y.A., Slight I., Volkmer-Engert R., Tamamura H., Fujii N., Bouvier M., and Heveker N. Bioluminescence resonance energy transfer reveals ligand-induced conformational changes in CXCR4 homo- and heterodimers. J. Biol. Chem. 280 (2005) 9895-9903
59. Plata-Salaman C.R. Cytokines and feeding. News Physiol. Sci. 13 (1998) 298-304
60. Plata-Salaman C.R. Cytokines and feeding. Int. J. Obes. Relat. Metab. Disord. 25 Suppl 5 (2001) S48-S52
61. Pringle A.K., Gardner C.R., and Walker R.J. Reduction of cerebellar GABAA responses by interleukin-1 (IL-1) through an indomethacin insensitive mechanism. Neuropharmacology 35 (1996) 147-152
62. Proost P., Struyf S., Schols D., Durinx C., Wuyts A., Lenaerts J.P., De Clercq E., De Meester I., and Van Damme J. Processing by CD26/dipeptidyl-peptidase IV reduces the chemotactic and anti-HIV-1 activity of stromal-cell-derived factor-1alpha. FEBS Lett. 432 (1998) 73-76
63. Puma C., Danik M., Quirion R., Ramon F., and Williams S. The chemokine interleukin-8 acutely reduces Ca(2+) currents in identified cholinergic septal neurons expressing CXCR1 and CXCR2 receptor mRNAs. J. Neurochem. 78 (2001) 960-971
64. Ragozzino D. CXC chemokine receptors in the central nervous system: Role in cerebellar neuromodulation and development. J. Neurovirol. 8 (2002) 559-572
65. Ragozzino D., Di Angelantonio S., Trettel F., Bertollini C., Maggi L., Gross C., Charo I.F., Limatola C., and Eusebi F. Chemokine fractalkine/CX3CL1 negatively modulates active glutamatergic synapses in rat hippocampal neurons. J. Neurosci. 26 (2006) 10488-10498
66. Rock R.B., Gekker G., Hu S., Sheng W.S., Cheeran M., Lokensgard J.R., and Peterson P.K. Role of microglia in central nervous system infections. Clin. Microbiol. Rev. 17 (2004) 942-964 table of contents
67. Rodriguez-Frade J.M., Mellado M., and Martinez A.C. Chemokine receptor dimerization: two are better than one. Trends Immunol. 22 (2001) 612-617
68. Rostene W., Kitabgi P., and Parsadaniantz S.M. Chemokines: a new class of neuromodulator?. Nat. Rev. Neurosci. 8 (2007) 895-903
69. Sachot C., Poole S., and Luheshi G.N. Circulating leptin mediates lipopolysaccharide-induced anorexia and fever in rats. J. Physiol 561 (2004) 263-272
70. Sadir R., Baleux F., Grosdidier A., Imberty A., and Lortat-Jacob H. Characterization of the stromal cell-derived factor-1alpha-heparin complex. J. Biol. Chem. 276 (2001) 8288-8296
71. Schönemeier B., Schulz S., Hoellt V., and Stumm R. Enhanced expression of the CXCL12/SDF-1 chemokine receptor CXCR7 after cerebral ischemia in the rat brain. J. Neuroimmunol 198 (2008) 39-45 10.1016/j.jneuroim.2008.04.010 (this issue)
72. Sergeyev V., Broberger C., and Hokfelt T. Effect of LPS administration on the expression of POMC, NPY, galanin, CART and MCH mRNAs in the rat hypothalamus. Brain Res. Mol. Brain Res. 90 (2001) 93-100
73. Skrzydelski D., Guyon A., Dauge V., Rovere C., Apartis E., Kitabgi P., Nahon J.L., Rostene W., and Parsadaniantz S.M. The chemokine stromal cell-derived factor-1/CXCL12 activates the nigrostriatal dopamine system. J. Neurochem. 102 (2007) 1175-1183
74. 2+ currents in cultured sympathetic neurons. J. Neurosci. 12 (1992) 2665-2671
75. Stoehr J.D., Cramer C.P., and North W.G. Oxytocin and vasopressin hexapeptide fragments have opposing influences on conditioned freezing behavior. Psychoneuroendocrinology 17 (1992) 267-271
76. Streit W.J., Conde J.R., and Harrison J.K. Chemokines and Alzheimer's disease. Neurobiol. Aging 22 (2001) 909-913
77. Stumm R., and Hollt V. CXC chemokine receptor 4 regulates neuronal migration and axonal pathfinding in the developing nervous system: implications for neuronal regeneration in the adult brain. J. Mol. Endocrinol. 38 (2007) 377-382
78. Szabo I., Chen X.H., Xin L., Adler M.W., Howard O.M., Oppenheim J.J., and Rogers T.J. Heterologous desensitization of opioid receptors by chemokines inhibits chemotaxis and enhances the perception of pain. Proc. Natl. Acad. Sci. U. S. A. 99 (2002) 10276-10281
79. 2+ activity at GABAB receptors constitutively promotes metabotropic glutamate signaling in the absence of GABA. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 16952-16957
80. Terrillon S., and Bouvier M. Roles of G-protein-coupled receptor dimerization. EMBO Rep. 5 (2004) 30-34
81. Toth P.T., Ren D., and Miller R.J. Regulation of CXCR4 receptor dimerization by the chemokine SDF-1alpha and the HIV-1 coat protein gp120: a fluorescence resonance energy transfer (FRET) study. J. Pharmacol. Exp. Ther. 310 (2004) 8-17
82. Tovar S., Nogueiras R., Tung L.Y., Castaneda T.R., Vazquez M.J., Morris A., Williams L.M., Dickson S.L., and Dieguez C. Central administration of resistin promotes short-term satiety in rats. Eur. J. Endocrinol. 153 (2005) R1-R5
83. Valenzuela-Fernandez A., Planchenault T., Baleux F., Staropoli I., Le-Barillec K., Leduc D., Delaunay T., Lazarini F., Virelizier J.L., Chignard M., Pidard D., and Arenzana-Seisdedos F. Leukocyte elastase negatively regulates stromal cell-derived factor-1 (SDF-1)/CXCR4 binding and functions by amino-terminal processing of SDF-1 and CXCR4. J. Biol. Chem. 277 (2002) 15677-15689
84. Valerio A., Ferrario M., Martinez F.O., Locati M., Ghisi V., Bresciani L.G., Mantovani A., and Spano P. Gene expression profile activated by the chemokine CCL5/RANTES in human neuronal cells. J. Neurosci. Res. 78 (2004) 371-382
85. Veldkamp C.T., Peterson F.C., Pelzek A.J., and Volkman B.F. The monomer-dimer equilibrium of stromal cell-derived factor-1 (CXCL 12) is altered by pH, phosphate, sulfate, and heparin. Protein Sci. 14 (2005) 1071-1081
86. Vila-Coro A.J., Rodriguez-Frade J.M., Martin De Ana A., Moreno-Ortiz M.C., Martinez A.C., and Mellado M. The chemokine SDF-1alpha triggers CXCR4 receptor dimerization and activates the JAK/STAT pathway. FASEB J. 13 (1999) 1699-1710
87. Vila M., Jackson-Lewis V., Guegan C., Wu D.C., Teismann P., Choi D.K., Tieu K., and Przedborski S. The role of glial cells in Parkinson's disease. Curr. Opin. Neurol. 14 (2001) 483-489
88. Wang L., Basa N.R., Shaikh A., Luckey A., Heber D., St-Pierre D.H., and Tache Y. LPS inhibits fasted plasma ghrelin levels in rats: role of IL-1 and PGs and functional implications. Am. J. Physiol. Gastrointest. Liver Physiol. 291 (2006) G611-G620
89. Weiland T.J., Kent S., Voudouris N.J., and Shulkes A. The effect of lipopolysaccharide on cholecystokinin in murine plasma and tissue. Peptides 26 (2005) 447-455
90. Wieczorek M., Swiergiel A.H., Pournajafi-Nazarloo H., and Dunn A.J. Physiological and behavioral responses to interleukin-1beta and LPS in vagotomized mice. Physiol. Behav. 85 (2005) 500-511
91. Wispelwey B., Lesse A.J., Hansen E.J., and Scheld W.M. Haemophilus influenzae lipopolysaccharide-induced blood brain barrier permeability during experimental meningitis in the rat. J. Clin. Invest. 82 (1988) 1339-1346
92. Yudkin J.S. Inflammation, obesity, and the metabolic syndrome. Horm. Metab. Res. 39 (2007) 707-709
93. Zhang K., McQuibban G.A., Silva C., Butler G.S., Johnston J.B., Holden J., Clark-Lewis I., Overall C.M., and Power C. HIV-induced metalloproteinase processing of the chemokine stromal cell derived factor-1 causes neurodegeneration. Nat. Neurosci. 6 (2003) 1064-1071
94. Zlatopolskiy A., and Laurence J. 'Reverse gear' cellular movement mediated by chemokines. Immunol. Cell Biol. 79 (2001) 340-344