SCOPUS 정보 검색 플랫폼

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 14, 2008, Pages 3899-3901

T-type Ca2+ channel blockers suppress the growth of human cancer cells

(10) Heo, Jae Ho a Seo, Han Na a Choe, Yun Jeong a Kim, Sujin a Oh, Chun Rim b Kim, Young Deuk b Rhim, Hyewhon c Choo, Dong Joon a Kim, Jungahn a Lee, Jae Yeol a

a Korea Basic Science Institute (KBSI) (South Korea)

b DongWoo Syntech Co Ltd (South Korea)

c Korea Institute of Science and Technology (South Korea)

Author keywords

3,4 Dihydroquinazoline; Anti cancer; Doxorubicin; T type calcium channel blocker

Indexed keywords

CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL T TYPE; DOXORUBICIN; KYS 05042; KYS 05043; KYS 05046; KYS 05047; KYS 05048; KYS 05055; KYS 05056; KYS 05057; KYS 05065; KYS 05080; KYS 05085; KYS 05089; KYS 05090; MIBEFRADIL; PIMOZIDE; ANTINEOPLASTIC AGENT; KYS05080; QUINAZOLINE DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CANCER INHIBITION; DRUG POTENCY; DRUG SCREENING; DRUG STRUCTURE; HUMAN; HUMAN CELL; ANIMAL; CELL PROLIFERATION; CHEMICAL MODEL; CHEMISTRY; DRUG DESIGN; IC 50; METABOLISM; METHODOLOGY; MOUSE; SYNTHESIS; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, T-TYPE; CELL LINE, TUMOR; CELL PROLIFERATION; CHEMISTRY, PHARMACEUTICAL; DOXORUBICIN; DRUG DESIGN; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; INHIBITORY CONCENTRATION 50; MICE; MODELS, CHEMICAL; QUINAZOLINES;

EID: 47249156681 PISSN: 0960894X EISSN: None Source Type: Journal
DOI: 10.1016/j.bmcl.2008.06.034 Document Type: Article

Times cited : (59)

References (24)

1
- 0034304906
- Berridge M.J., Lipp P., and Bootman M.D. Nat. Rev. Mol. Cell Biol. 1 (2000) 11
- (2000) Nat. Rev. Mol. Cell Biol. , vol.1 , pp. 11
- Berridge, M.J.¹ Lipp, P.² Bootman, M.D.³

2
- 0032127595
- Berridge M.J. Neuron 21 (1998) 13
- (1998) Neuron , vol.21 , pp. 13
- Berridge, M.J.¹

3
- 33745671356
- Lory P., Bidaud I., and Chemin J. Cell Calcium 40 (2006) 135
- (2006) Cell Calcium , vol.40 , pp. 135
- Lory, P.¹ Bidaud, I.² Chemin, J.³

4
- 33745370071
- Gray L.S., and Macdonaldm T.L. Cell Calcium 40 (2006) 115
- (2006) Cell Calcium , vol.40 , pp. 115
- Gray, L.S.¹ Macdonaldm, T.L.²

5
- 2942536387
- McCalmont W.F., Heady T.N., Patterson J.R., Lindenmuth M.A., Haverstick D.M., Gray L.S., and Macdonald T.L. Bioorg. Med. Chem. Lett. 14 (2004) 3691
- (2004) Bioorg. Med. Chem. Lett. , vol.14 , pp. 3691
- McCalmont, W.F.¹ Heady, T.N.² Patterson, J.R.³ Lindenmuth, M.A.⁴ Haverstick, D.M.⁵ Gray, L.S.⁶ Macdonald, T.L.⁷

6
- 18144388003
- McCalmont W.F., Patterson J.R., Lindenmuth M.A., Heady T.N., Haverstick D.M., Gray L.S., and Macdonald T.L. Bioorg. Med. Chem. 13 (2005) 3821
- (2005) Bioorg. Med. Chem. , vol.13 , pp. 3821
- McCalmont, W.F.¹ Patterson, J.R.² Lindenmuth, M.A.³ Heady, T.N.⁴ Haverstick, D.M.⁵ Gray, L.S.⁶ Macdonald, T.L.⁷

7
- 13844255564
- Chen H.-T., Chang W.-C., Chen J.-S., Lu Y.-C., Hsu S.-S., Wang J.-L., Cheng H.-H., Cheng J.-S., Jiann B.-P., Chiang A.-J., Huang J.-K., and Jan C.-R. Life Sci. 76 (2005) 2091
- (2005) Life Sci. , vol.76 , pp. 2091
- Chen, H.-T.¹ Chang, W.-C.² Chen, J.-S.³ Lu, Y.-C.⁴ Hsu, S.-S.⁵ Wang, J.-L.⁶ Cheng, H.-H.⁷ Cheng, J.-S.⁸ Jiann, B.-P.⁹ Chiang, A.-J.¹⁰ Huang, J.-K.¹¹ Jan, C.-R.¹²

8
- 0034652479
- Haverstick D.M., Heady T.N., Macdonald T.L., and Gray L.S. Cancer Res. 60 (2000) 1002
- (2000) Cancer Res. , vol.60 , pp. 1002
- Haverstick, D.M.¹ Heady, T.N.² Macdonald, T.L.³ Gray, L.S.⁴

9
- 0029093659
- Schmitt R., Clozel J.P., Iberg N., and Buhler F.R. Arterioscler. Thromb. Vasc. Biol. 15 (1995) 1161
- (1995) Arterioscler. Thromb. Vasc. Biol. , vol.15 , pp. 1161
- Schmitt, R.¹ Clozel, J.P.² Iberg, N.³ Buhler, F.R.⁴

10
- 20944438626
- Rodman D.M., Reese K., Harral J., Fouty B., Wu S., West J., Hoedt-Miller M., Tada Y., Li K.X., Cool C., Fagan K., and Cribbs L. Circ. Res. 96 (2005) 864
- (2005) Circ. Res. , vol.96 , pp. 864
- Rodman, D.M.¹ Reese, K.² Harral, J.³ Fouty, B.⁴ Wu, S.⁵ West, J.⁶ Hoedt-Miller, M.⁷ Tada, Y.⁸ Li, K.X.⁹ Cool, C.¹⁰ Fagan, K.¹¹ Cribbs, L.¹²

11
- 0031011248
- Nilius B., Prenen J., Kamouchi M., Viana F., Voets T., and Droogmans G. Br. J. Pharmacol. 121 (1997) 547
- (1997) Br. J. Pharmacol. , vol.121 , pp. 547
- Nilius, B.¹ Prenen, J.² Kamouchi, M.³ Viana, F.⁴ Voets, T.⁵ Droogmans, G.⁶

12
- 0032956821
- Lijnen P., Fagard R., and Petrov V. J. Cardiovasc. Pharmacol. 33 (1999) 595
- (1999) J. Cardiovasc. Pharmacol. , vol.33 , pp. 595
- Lijnen, P.¹ Fagard, R.² Petrov, V.³

13
- 0035336894
- Wondergem R., Gong W., Monen S.H., Dooley S.N., Gonce J.L., Conner T.D., Houser M., Ecay T.W., and Ferslew K.E. J. Physiol. 532 (2001) 661
- (2001) J. Physiol. , vol.532 , pp. 661
- Wondergem, R.¹ Gong, W.² Monen, S.H.³ Dooley, S.N.⁴ Gonce, J.L.⁵ Conner, T.D.⁶ Houser, M.⁷ Ecay, T.W.⁸ Ferslew, K.E.⁹

14
- 10944232060
- Panner A., Cribbs L.L., Zainelli G.M., Origitano T.C., Singh S., and Wurster R.D. Cell Calcium 37 (2005) 105
- (2005) Cell Calcium , vol.37 , pp. 105
- Panner, A.¹ Cribbs, L.L.² Zainelli, G.M.³ Origitano, T.C.⁴ Singh, S.⁵ Wurster, R.D.⁶

15
- 0031795268
- Strobl J.S., Melkoumian Z., Peterson V.A., and Hylton H. Breast Cancer Res. Treat. 51 (1998) 83
- (1998) Breast Cancer Res. Treat. , vol.51 , pp. 83
- Strobl, J.S.¹ Melkoumian, Z.² Peterson, V.A.³ Hylton, H.⁴

16
- 37849017902
- Lu F., Chen H., Zhou C., Liu S., Guo M., Chen P., Zhuang H., Xie D., and Wu S. Cell Calcium 43 (2008) 49
- (2008) Cell Calcium , vol.43 , pp. 49
- Lu, F.¹ Chen, H.² Zhou, C.³ Liu, S.⁴ Guo, M.⁵ Chen, P.⁶ Zhuang, H.⁷ Xie, D.⁸ Wu, S.⁹

17
- 33747334641
- Lee J.Y., Park S.J., Park S.J., Lee M.J., Lee M.J., Rhim H., Seo S.H., and Kim K.-S. Bioorg. Med. Chem. Lett. 16 (2006) 5014
- (2006) Bioorg. Med. Chem. Lett. , vol.16 , pp. 5014
- Lee, J.Y.¹ Park, S.J.² Park, S.J.³ Lee, M.J.⁴ Lee, M.J.⁵ Rhim, H.⁶ Seo, S.H.⁷ Kim, K.-S.⁸

18
- 2942531077
- Lee Y.S., Lee B.H., Park S.J., Kang S.B., Rhim H., Park J.-Y., Lee J.-H., Jeong S.-W., and Lee J.Y. Bioorg. Med. Chem. Lett. 14 (2004) 3379
- (2004) Bioorg. Med. Chem. Lett. , vol.14 , pp. 3379
- Lee, Y.S.¹ Lee, B.H.² Park, S.J.³ Kang, S.B.⁴ Rhim, H.⁵ Park, J.-Y.⁶ Lee, J.-H.⁷ Jeong, S.-W.⁸ Lee, J.Y.⁹

19
- 10644273394
- Rhim H., Lee Y.S., Park S.J., Chung B.Y., and Lee J.Y. Bioorg. Med. Chem. Lett. 15 (2005) 283
- (2005) Bioorg. Med. Chem. Lett. , vol.15 , pp. 283
- Rhim, H.¹ Lee, Y.S.² Park, S.J.³ Chung, B.Y.⁴ Lee, J.Y.⁵

20
- 33645860533
- Park S.J., Park S.J., Lee M.J., Rhim H., Kim Y., Lee J.-H., Chung B.Y., and Lee J.Y. Bioorg. Med. Chem. 14 (2006) 3502
- (2006) Bioorg. Med. Chem. , vol.14 , pp. 3502
- Park, S.J.¹ Park, S.J.² Lee, M.J.³ Rhim, H.⁴ Kim, Y.⁵ Lee, J.-H.⁶ Chung, B.Y.⁷ Lee, J.Y.⁸

21
- 33846054064
- Choi J.Y., Seo H.N., Lee M.J., Park S.J., Park S.J., Jeon J.Y., Kang J.H., Pae A.N., Rhim H., and Lee J.Y. Bioorg. Med. Chem. Lett. 17 (2007) 471
- (2007) Bioorg. Med. Chem. Lett. , vol.17 , pp. 471
- Choi, J.Y.¹ Seo, H.N.² Lee, M.J.³ Park, S.J.⁴ Park, S.J.⁵ Jeon, J.Y.⁶ Kang, J.H.⁷ Pae, A.N.⁸ Rhim, H.⁹ Lee, J.Y.¹⁰

22
- 34548828834
- Seo H.N., Choi J.Y., Choe Y.J., Kim Y., Rhim H., Lee S.H., Kim J., Joo D.J., and Lee J.Y. Bioorg. Med. Chem. Lett. 17 (2007) 5740
- (2007) Bioorg. Med. Chem. Lett. , vol.17 , pp. 5740
- Seo, H.N.¹ Choi, J.Y.² Choe, Y.J.³ Kim, Y.⁴ Rhim, H.⁵ Lee, S.H.⁶ Kim, J.⁷ Joo, D.J.⁸ Lee, J.Y.⁹

23
- 4744357332
- 50) were determined from fitting raw data into dose-response curves. The current recordings were obtained using an EPC-9 amplifier and Pulse/Pulsefit software program (HEKA, Germany)
- 50) were determined from fitting raw data into dose-response curves. The current recordings were obtained using an EPC-9 amplifier and Pulse/Pulsefit software program (HEKA, Germany)
- (2004) Biochem. Biophys. Res. Commun. , vol.324 , pp. 401
- Kim, T.¹ Choi, J.² Kim, S.³ Kwon, O.⁴ Nah, S.Y.⁵ Han, Y.S.⁶ Rhim, H.⁷

24
- 0025341331
- 2 for 72 h such that time cells are in the exponential phase of growth at the time of drug addition. After incubation, the 100 μL of formalin solution was gently added to the wells. Microplates were left for 30 min at room temperature, washed 5 times with tap water. The 100 μL of 0.4% SRB solution was added to each well and left at room temperature for 30 min. SRB was removed and the plates were washed 5 times with 1% acetic acid before air drying. Bound SRB was solubilized with 100 μL of 10 mM unbuffered Tris-base solution (Sigma) and plates were left on a plate shaker for at least 10 min.
- 50
- (1990) J. Natl. Cancer Inst. , vol.82 , pp. 1107
- Skehan, P.¹ Streng, R.² Scudiero, D.³ Monks, A.⁴ McMahon, J.⁵ Vistica, D.⁶ Warren, J.T.⁷ Bokesch, H.⁸ Kenney, S.⁹ Boyd, M.R.¹⁰

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.