Synthesis and biological evaluation of novel T-type calcium channel blockers

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 2, 2007, Pages 471-475

  Choi, Ja Youn ^a   Seo, Han Na ^a   Lee, Min Joo ^a   Park, Seong Jun ^b,c   Park, Sung Jun ^a   Jeon, Ji Young ^a   Kang, Joo Hi ^a   Pae, Ae Nim ^b   Rhim, Hyewhon ^b   Lee, Jae Yeol ^a  

^a Korea Basic Science Institute (KBSI)   (South Korea)

^b Korea Institute of Science and Technology   (South Korea)

^c Korea University   (South Korea)

Author keywords

3,4 Dihydroquinazoline; Channel blockers; Regioisomers; T type calcium channel

Indexed keywords

CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL T TYPE; KYS 05044; KYS 05050; KYS 05076; KYS 05077; KYS 05079; KYS 05080; MIBEFRADIL; QUINAZOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BIOLOGICAL ACTIVITY; DRUG EFFECT; DRUG SELECTIVITY; DRUG SYNTHESIS; EMBRYO; HUMAN; HUMAN CELL; IC 50;

ANIMALS; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, N-TYPE; CALCIUM CHANNELS, T-TYPE; CELL LINE, TUMOR; CRYSTALLOGRAPHY, X-RAY; INDICATORS AND REAGENTS; MAGNETIC RESONANCE SPECTROSCOPY; MIBEFRADIL; MODELS, MOLECULAR; OOCYTES; PYRROLIDINES; QUINAZOLINES; XENOPUS;

EID: 33846054064     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.10.024     Document Type: Article

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