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Volumn 1130, Issue , 2008, Pages 280-286

Flow cytometric FRET analysis of erbB receptor interaction on a cell-by-cell basis

Author keywords

Breast cancer; c erbB2 homodimerization; FCET; Flow cytometry; FRET; Pertuzumab; Receptor interaction; Trastuzumab

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; HOMODIMER; MONOCLONAL ANTIBODY; PERTUZUMAB; TRASTUZUMAB;

EID: 47249112974     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1196/annals.1430.003     Document Type: Conference Paper
Times cited : (17)

References (30)
  • 1
    • 0035430589 scopus 로고    scopus 로고
    • Epidermal growth factor receptor, c-erbB2 and c-erbB3 receptor interaction, and related cell cycle kinetics of SK-BR-3 and BT474 breast carcinoma cells
    • Brockhoff, G., P. Heiss, et al. 2001. Epidermal growth factor receptor, c-erbB2 and c-erbB3 receptor interaction, and related cell cycle kinetics of SK-BR-3 and BT474 breast carcinoma cells. Cytometry 44 : 338 348.
    • (2001) Cytometry , vol.44 , pp. 338-348
    • Brockhoff, G.1    Heiss, P.2
  • 2
    • 14644392200 scopus 로고    scopus 로고
    • Epidermal growth factor receptor coexpression modulates susceptibility to Herceptin in HER2/neu overexpressing breast cancer cells via specific erbB-receptor interaction and activation
    • Diermeier, S., G. Horvath, et al. 2005. Epidermal growth factor receptor coexpression modulates susceptibility to Herceptin in HER2/neu overexpressing breast cancer cells via specific erbB-receptor interaction and activation. Exp. Cell Res. 304 : 604 619.
    • (2005) Exp. Cell Res. , vol.304 , pp. 604-619
    • Diermeier, S.1    Horvath, G.2
  • 3
    • 0032101894 scopus 로고    scopus 로고
    • EGF-induced redistribution of erbB2 on breast tumor cells: Flow and image cytometric energy transfer measurements
    • Nagy, P., L. Bene, et al. 1998. EGF-induced redistribution of erbB2 on breast tumor cells: flow and image cytometric energy transfer measurements. Cytometry 32 : 120 131.
    • (1998) Cytometry , vol.32 , pp. 120-131
    • Nagy, P.1    Bene, L.2
  • 4
    • 0037246549 scopus 로고    scopus 로고
    • Fluorescence resonance energy transfer in the study of cancer pathways
    • &
    • Schmid, J.A. & H.H. Sitte. 2003. Fluorescence resonance energy transfer in the study of cancer pathways. Curr. Opin. Oncol. 15 : 55 64.
    • (2003) Curr. Opin. Oncol. , vol.15 , pp. 55-64
    • Schmid, J.A.1    Sitte, H.H.2
  • 5
    • 0021273333 scopus 로고
    • Flow cytometric measurement of fluorescence resonance energy transfer on cell surfaces. Quantitative evaluation of the transfer efficiency on a cell-by-cell basis
    • Tron, L., J. Szollosi, et al. 1984. Flow cytometric measurement of fluorescence resonance energy transfer on cell surfaces. Quantitative evaluation of the transfer efficiency on a cell-by-cell basis. Biophys. J. 45 : 939 946.
    • (1984) Biophys. J. , vol.45 , pp. 939-946
    • Tron, L.1    Szollosi, J.2
  • 6
    • 0030944455 scopus 로고    scopus 로고
    • ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling
    • Graus-Porta, D., R.R. Beerli, et al. 1997. ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling. EMBO J. 16 : 1647 1655.
    • (1997) EMBO J. , vol.16 , pp. 1647-1655
    • Graus-Porta, D.1    Beerli, R.R.2
  • 8
    • 21644438384 scopus 로고    scopus 로고
    • The diverse signaling network of EGFR, HER2, HER3 and HER4 tyrosine kinase receptors and the consequences for therapeutic approaches
    • Zaczek, A., B. Brandt, et al. 2005. The diverse signaling network of EGFR, HER2, HER3 and HER4 tyrosine kinase receptors and the consequences for therapeutic approaches. Histol. Histopathol. 20 : 1005 1015.
    • (2005) Histol. Histopathol. , vol.20 , pp. 1005-1015
    • Zaczek, A.1    Brandt, B.2
  • 9
    • 37049183697 scopus 로고
    • Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
    • Slamon, D.J., G.M. Clark, et al. 1987. Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 235 : 177 182.
    • (1987) Science , vol.235 , pp. 177-182
    • Slamon, D.J.1    Clark, G.M.2
  • 10
    • 33644600485 scopus 로고    scopus 로고
    • Humanization of a recombinant monoclonal antibody to produce a therapeutic HER dimerization inhibitor, Pertuzumab
    • Adams, C.W., D.E. Allison, et al. 2006. Humanization of a recombinant monoclonal antibody to produce a therapeutic HER dimerization inhibitor, Pertuzumab. Cancer Immunol. Immunother. 55 : 717 727.
    • (2006) Cancer Immunol. Immunother. , vol.55 , pp. 717-727
    • Adams, C.W.1    Allison, D.E.2
  • 11
    • 0141645488 scopus 로고    scopus 로고
    • Mechanism of action of anti-HER2 monoclonal antibodies: Scientific update on trastuzumab and 2C4
    • Albanell, J., J. Codony, et al. 2003. Mechanism of action of anti-HER2 monoclonal antibodies: scientific update on trastuzumab and 2C4. Adv. Exp. Med. Biol. 532 : 253 268.
    • (2003) Adv. Exp. Med. Biol. , vol.532 , pp. 253-268
    • Albanell, J.1    Codony, J.2
  • 12
    • 0036187710 scopus 로고    scopus 로고
    • NH(2)-terminal truncated HER-2 protein but not full-length receptor is associated with nodal metastasis in human breast cancer
    • Molina, M.A., R. Saez, et al. 2002. NH(2)-terminal truncated HER-2 protein but not full-length receptor is associated with nodal metastasis in human breast cancer. Clin. Cancer Res. 8 : 347 353.
    • (2002) Clin. Cancer Res. , vol.8 , pp. 347-353
    • Molina, M.A.1    Saez, R.2
  • 13
    • 19044380618 scopus 로고    scopus 로고
    • Targeting ligand-activated ErbB2 signaling inhibits breast and prostate tumor growth
    • Agus, D.B., R.W. Akita, et al. 2002. Targeting ligand-activated ErbB2 signaling inhibits breast and prostate tumor growth. Cancer Cell. 2 : 127 137.
    • (2002) Cancer Cell. , vol.2 , pp. 127-137
    • Agus, D.B.1    Akita, R.W.2
  • 14
    • 0013503143 scopus 로고    scopus 로고
    • A new anti-ErbB2 strategy in the treatment of cancer: Prevention of ligand-dependent ErbB2 receptor heterodimerization
    • Baselga, J. 2002. A new anti-ErbB2 strategy in the treatment of cancer: prevention of ligand-dependent ErbB2 receptor heterodimerization. Cancer Cell. 2 : 93 95.
    • (2002) Cancer Cell. , vol.2 , pp. 93-95
    • Baselga, J.1
  • 15
    • 47249145751 scopus 로고    scopus 로고
    • Flow cytometric FRET analysis of (erbB-) receptor-tyrosine-kinase interaction
    • & Submitted to
    • Diermeier-Daucher, S. & G. Brockhoff. 2007. Flow cytometric FRET analysis of (erbB-) receptor-tyrosine-kinase interaction. Submitted to Current Protocols in Cytometry.
    • (2007) Current Protocols in Cytometry.
    • Diermeier-Daucher, S.1    Brockhoff, G.2
  • 16
    • 26444493680 scopus 로고    scopus 로고
    • Computer program for analyzing donor photobleaching FRET image series
    • Szentesi, G., G. Vereb, et al. 2005. Computer program for analyzing donor photobleaching FRET image series. Cytometry A. 67 : 119 128.
    • (2005) Cytometry A. , vol.67 , pp. 119-128
    • Szentesi, G.1    Vereb, G.2
  • 17
    • 34447336165 scopus 로고    scopus 로고
    • Differential impact of Cetuximab, Pertuzumab and Trastuzumab on BT474 and SK-BR-3 breast cancer cell proliferation
    • Brockhoff, G., B. Heckel, et al. 2007. Differential impact of Cetuximab, Pertuzumab and Trastuzumab on BT474 and SK-BR-3 breast cancer cell proliferation. Cell Prolif. 40 : 488 507.
    • (2007) Cell Prolif. , vol.40 , pp. 488-507
    • Brockhoff, G.1    Heckel, B.2
  • 18
    • 1842608521 scopus 로고    scopus 로고
    • Exposure to continuous bromodeoxyuridine (BrdU) differentially affects cell cycle progression of human breast and bladder cancer cell lines
    • Diermeier, S., E. Schmidt-Bruecken, et al. 2004. Exposure to continuous bromodeoxyuridine (BrdU) differentially affects cell cycle progression of human breast and bladder cancer cell lines. Cell Prolif. 37 : 195 206.
    • (2004) Cell Prolif. , vol.37 , pp. 195-206
    • Diermeier, S.1    Schmidt-Bruecken, E.2
  • 19
    • 1842499086 scopus 로고    scopus 로고
    • High-resolution cell cycle analysis: The flow cytometric bromodeoxyuridine-Hoechst quenching technique
    • In. A. Radbruch, Ed., 2nd ed., pp. Springer. Berlin, Heidelberg, New York.
    • Kubbies, M. 1999. High-resolution cell cycle analysis: the flow cytometric bromodeoxyuridine-Hoechst quenching technique. In Flow Cytometry and Cell Sorting, 2nd ed. A. Radbruch, Ed., 2nd ed., pp. 112 124. Springer. Berlin, Heidelberg, New York.
    • (1999) Flow Cytometry and Cell Sorting, 2nd Ed. , pp. 112-124
    • Kubbies, M.1
  • 20
    • 0036628631 scopus 로고    scopus 로고
    • Long wavelength fluorophores and cell-by-cell correction for autofluorescence significantly improves the accuracy of flow cytometric energy transfer measurements on a dual-laser benchtop flow cytometer
    • Sebestyen, Z., P. Nagy, et al. 2002. Long wavelength fluorophores and cell-by-cell correction for autofluorescence significantly improves the accuracy of flow cytometric energy transfer measurements on a dual-laser benchtop flow cytometer. Cytometry 48 : 124 135.
    • (2002) Cytometry , vol.48 , pp. 124-135
    • Sebestyen, Z.1    Nagy, P.2
  • 21
    • 0037434791 scopus 로고    scopus 로고
    • Structure of the extracellular region of HER2 alone and in complex with the Herceptin Fab
    • Cho, H.S., K. Mason, et al. 2003. Structure of the extracellular region of HER2 alone and in complex with the Herceptin Fab. Nature 421 : 756 760.
    • (2003) Nature , vol.421 , pp. 756-760
    • Cho, H.S.1    Mason, K.2
  • 22
    • 2542555865 scopus 로고    scopus 로고
    • A new therapeutic antibody masks ErbB2 to its partners
    • &
    • Badache, A. & N.E. Hynes. 2004. A new therapeutic antibody masks ErbB2 to its partners. Cancer Cell. 5 : 299 301.
    • (2004) Cancer Cell. , vol.5 , pp. 299-301
    • Badache, A.1    Hynes, N.E.2
  • 23
    • 33746570816 scopus 로고    scopus 로고
    • Targeting HER2 Epitopes
    • &
    • Pal, S.K. & M. Pegram. 2006. Targeting HER2 Epitopes. Sem. Oncol. 33 : 386 389.
    • (2006) Sem. Oncol. , vol.33 , pp. 386-389
    • Pal, S.K.1    Pegram, M.2
  • 24
    • 25144517586 scopus 로고    scopus 로고
    • Evaluation of clinical outcomes according to HER2 detection by fluorescence in situ hybridization in women with metastatic breast cancer treated with Trastuzumab
    • Mass, R.D., M.F. Press, et al. 2005. Evaluation of clinical outcomes according to HER2 detection by fluorescence in situ hybridization in women with metastatic breast cancer treated with Trastuzumab. Clin. Breast Cancer 6 : 240 246.
    • (2005) Clin. Breast Cancer , vol.6 , pp. 240-246
    • Mass, R.D.1    Press, M.F.2
  • 25
    • 0032532950 scopus 로고    scopus 로고
    • NH2-terminally truncated HER-2/neu protein: Relationship with shedding of the extracellular domain and with prognostic factors in breast cancer
    • Christianson, T.A., J.K. Doherty, et al. 1998. NH2-terminally truncated HER-2/neu protein: relationship with shedding of the extracellular domain and with prognostic factors in breast cancer. Cancer Res. 58 : 5123 5129.
    • (1998) Cancer Res. , vol.58 , pp. 5123-5129
    • Christianson, T.A.1    Doherty, J.K.2
  • 26
    • 0026071364 scopus 로고
    • The extracellular domain of p185/neu is released from the surface of human breast carcinoma cells, SK-BR-3
    • Zabrecky, J.R., T. Lam, et al. 1991. The extracellular domain of p185/neu is released from the surface of human breast carcinoma cells, SK-BR-3. J. Biol. Chem. 266 : 1716 1720.
    • (1991) J. Biol. Chem. , vol.266 , pp. 1716-1720
    • Zabrecky, J.R.1    Lam, T.2
  • 27
    • 1942474587 scopus 로고    scopus 로고
    • The HER-2-targeting antibodies trastuzumab and pertuzumab synergistically inhibit the survival of breast cancer cells
    • Nahta, R., M.C. Hung, et al. 2004. The HER-2-targeting antibodies trastuzumab and pertuzumab synergistically inhibit the survival of breast cancer cells. Cancer Res. 64 : 2343 2346.
    • (2004) Cancer Res. , vol.64 , pp. 2343-2346
    • Nahta, R.1    Hung, M.C.2
  • 28
    • 30544449081 scopus 로고    scopus 로고
    • A quantitative protein interaction network for the ErbB receptors using protein microarrays
    • Jones, R.B., A. Gordus, et al. 2006. A quantitative protein interaction network for the ErbB receptors using protein microarrays. Nature 439 : 168 174.
    • (2006) Nature , vol.439 , pp. 168-174
    • Jones, R.B.1    Gordus, A.2
  • 30
    • 47249118083 scopus 로고    scopus 로고
    • Cytogenetic analysis of HER1/EGFR, HER2, HER3, and HER4 in 278 breast cancer patients
    • submittedLabeling scheme for flow cytometric c-erbB2 homodimerization assessment with FRET. Trastuzumab (A) or pertuzumab (B) treated FRET samples were stained separately with Cy3 (donor dye) and Cy5 (acceptor dye) conjugated pertuzumab (A) or trastuzumab (B), respectively.
    • Sassen, A., J. Rochon, et al. 2007. Cytogenetic analysis of HER1/EGFR, HER2, HER3, and HER4 in 278 breast cancer patients. Breast Cancer Res. submitted Labeling scheme for flow cytometric c-erbB2 homodimerization assessment with FRET. Trastuzumab (A) or pertuzumab (B) treated FRET samples were stained separately with Cy3 (donor dye) and Cy5 (acceptor dye) conjugated pertuzumab (A) or trastuzumab (B), respectively.
    • (2007) Breast Cancer Res.
    • Sassen, A.1    Rochon, J.2


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