-
1
-
-
0036716281
-
The Bcl2 family: Regulators of the cellular life-or-death switch
-
Cory S, Adams JM. The Bcl2 family: Regulators of the cellular life-or-death switch. Nat Rev Cancer 2002; 2: 647-656.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 647-656
-
-
Cory, S.1
Adams, J.M.2
-
2
-
-
0035957653
-
Proapoptofic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death
-
Wei MC, Zong WX, Chang EH, Lindsten T, Panoutsakopoulou V, Ross AJ et al. Proapoptofic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death. Science 2001; 292: 727-730.
-
(2001)
Science
, vol.292
, pp. 727-730
-
-
Wei, M.C.1
Zong, W.X.2
Chang, E.H.3
Lindsten, T.4
Panoutsakopoulou, V.5
Ross, A.J.6
-
3
-
-
0034678367
-
Integrin-mediated survival signals regulate the apoptotic function of Bax through its conformation and subcellular localization
-
Gilmore AP, Metcalfe AM, Romer LH, Streuli CH. Integrin-mediated survival signals regulate the apoptotic function of Bax through its conformation and subcellular localization. J Cell Biol 2000; 149: 431-445.
-
(2000)
J Cell Biol
, vol.149
, pp. 431-445
-
-
Gilmore, A.P.1
Metcalfe, A.M.2
Romer, L.H.3
Streuli, C.H.4
-
4
-
-
0032487582
-
Regulated targeting of BAX to mitochondria
-
Goping IS, Gross A, Lavoie JN, Nguyen M, Jemmerson P, Roth K et al Regulated targeting of BAX to mitochondria. J Cell Biol 1998; 143: 207-215.
-
(1998)
J Cell Biol
, vol.143
, pp. 207-215
-
-
Goping, I.S.1
Gross, A.2
Lavoie, J.N.3
Nguyen, M.4
Jemmerson, P.5
Roth, K.6
-
5
-
-
0035853811
-
Bax is present as a high molecular weight oligomer/complex in the mitochondrial membrane of apoptotic cells
-
Antonsson B, Montessuit S, Sanchez B, Martinou JC. Bax is present as a high molecular weight oligomer/complex in the mitochondrial membrane of apoptotic cells. J Biol Chem 2001; 276: 11615-11623.
-
(2001)
J Biol Chem
, vol.276
, pp. 11615-11623
-
-
Antonsson, B.1
Montessuit, S.2
Sanchez, B.3
Martinou, J.C.4
-
6
-
-
0033535350
-
Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis
-
Desagher S, Osen Sand A, Nichols A, Eskes R, Montessuit S, Lauper S et al. Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis. J Cell Biol 1999; 144: 891-901.
-
(1999)
J Cell Biol
, vol.144
, pp. 891-901
-
-
Desagher, S.1
Osen Sand, A.2
Nichols, A.3
Eskes, R.4
Montessuit, S.5
Lauper, S.6
-
7
-
-
0033981577
-
Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane
-
Eskes R, Desagher S, Antonsson B, Martinou JC. Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane. Mol Cel Biol 2000; 20: 929-935.
-
(2000)
Mol Cel Biol
, vol.20
, pp. 929-935
-
-
Eskes, R.1
Desagher, S.2
Antonsson, B.3
Martinou, J.C.4
-
8
-
-
0030963602
-
Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis
-
Hsu YT, Wolter KG, Youle RJ. Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis. Proc Natl Acad Sci USA 1997; 94 3668-3672.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 3668-3672
-
-
Hsu, Y.T.1
Wolter, K.G.2
Youle, R.J.3
-
9
-
-
0041977046
-
Spatial and temporal changes in Bax subcellular localization during anoikis
-
Valentijn AJ, Metcalfe AD, Kott J, Streuli CH, Gilmore AP. Spatial and temporal changes in Bax subcellular localization during anoikis. J Cell Biol 2003; 162: 599-612.
-
(2003)
J Cell Biol
, vol.162
, pp. 599-612
-
-
Valentijn, A.J.1
Metcalfe, A.D.2
Kott, J.3
Streuli, C.H.4
Gilmore, A.P.5
-
10
-
-
0030780106
-
Movement of Bax from the cytosol to mitochondria during apoptosis
-
Wolter KG, Hsu YT, Smith CL, Nechushtan A, Xi XG, Youle RJ. Movement of Bax from the cytosol to mitochondria during apoptosis. J Cell Biol 1997; 139: 1281-1292.
-
(1997)
J Cell Biol
, vol.139
, pp. 1281-1292
-
-
Wolter, K.G.1
Hsu, Y.T.2
Smith, C.L.3
Nechushtan, A.4
Xi, X.G.5
Youle, R.J.6
-
11
-
-
0035344460
-
Versatility of the mitochondrial protein import machinery
-
Planner N, Geissler A. Versatility of the mitochondrial protein import machinery. Nat Rev Mol Cell Biol 2001; 2: 339-349.
-
(2001)
Nat Rev Mol Cell Biol
, vol.2
, pp. 339-349
-
-
Planner, N.1
Geissler, A.2
-
12
-
-
34547937485
-
How tails guide tail-anchored proteins to their destinations
-
Borgese N, Brambillasca S, Colombo S. How tails guide tail-anchored proteins to their destinations. Curr Opin Cell Biol 2007; 19 368-375.
-
(2007)
Curr Opin Cell Biol
, vol.19
, pp. 368-375
-
-
Borgese, N.1
Brambillasca, S.2
Colombo, S.3
-
13
-
-
0036000002
-
Characterization of signal that directs C-tail-anchored proteins to mammalian mitochondrial outer membrane
-
Horie C, Suzuki H, Sakaguchi M, Where K. Characterization of signal that directs C-tail-anchored proteins to mammalian mitochondrial outer membrane. Mol Biol Cell 2002; 13: 1615-1625.
-
(2002)
Mol Biol Cell
, vol.13
, pp. 1615-1625
-
-
Horie, C.1
Suzuki, H.2
Sakaguchi, M.3
Where, K.4
-
14
-
-
0037421190
-
Characterization of the signal that directs Bcl-x(L), but not Bcl-2, to the mitochondrial outer membrane
-
Kaufmann T, Schlipf S, Sanz J, Neubert K, Stain R, Bomer C. Characterization of the signal that directs Bcl-x(L), but not Bcl-2, to the mitochondrial outer membrane. J Cell Biol 2003; 160: 53-64.
-
(2003)
J Cell Biol
, vol.160
, pp. 53-64
-
-
Kaufmann, T.1
Schlipf, S.2
Sanz, J.3
Neubert, K.4
Stain, R.5
Bomer, C.6
-
15
-
-
1442359881
-
Bcl-2 family members: Intracellular targeting, membrane-insertion, and changes in subcellular localization
-
Schinzel A, Kaufmann T, Bomer C. Bcl-2 family members: Intracellular targeting, membrane-insertion, and changes in subcellular localization. Biochim Biophys Acta 2004; 1644: 95-105.
-
(2004)
Biochim Biophys Acta
, vol.1644
, pp. 95-105
-
-
Schinzel, A.1
Kaufmann, T.2
Bomer, C.3
-
16
-
-
0027166048
-
Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
-
Oltvai ZN, Milliman CL, Korsmeyer SJ. Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 1993; 74: 609-619.
-
(1993)
Cell
, vol.74
, pp. 609-619
-
-
Oltvai, Z.N.1
Milliman, C.L.2
Korsmeyer, S.J.3
-
17
-
-
15444364107
-
Distinct domains control the addressing and the insertion of Bax into mitochondria
-
Cartron PF, Arokium H, Oliver L, Meflah K, Manon S, Vallette FM. Distinct domains control the addressing and the insertion of Bax into mitochondria. J Biol Chem 2005; 280: 10587-10598.
-
(2005)
J Biol Chem
, vol.280
, pp. 10587-10598
-
-
Cartron, P.F.1
Arokium, H.2
Oliver, L.3
Meflah, K.4
Manon, S.5
Vallette, F.M.6
-
18
-
-
0038515279
-
The N-terminal end of Bax contains a mitochondrial-targeting signal
-
Cartron PF, Priault M, Oliver L, Meflah K, Manon S, Vallefte FM. The N-terminal end of Bax contains a mitochondrial-targeting signal. J Biol Chem 2003; 278: 11633-11641.
-
(2003)
J Biol Chem
, vol.278
, pp. 11633-11641
-
-
Cartron, P.F.1
Priault, M.2
Oliver, L.3
Meflah, K.4
Manon, S.5
Vallefte, F.M.6
-
19
-
-
0037070160
-
Involvement of the N-terminus of Bax in its intracellular localization and function
-
Cartron PF, Moreau C, Oliver L, Mayat E, Meflah K, Vallette FM. Involvement of the N-terminus of Bax in its intracellular localization and function. FEBS Lett 2002; 512: 95-100.
-
(2002)
FEBS Lett
, vol.512
, pp. 95-100
-
-
Cartron, P.F.1
Moreau, C.2
Oliver, L.3
Mayat, E.4
Meflah, K.5
Vallette, F.M.6
-
20
-
-
0033553997
-
The C-terminus of bax is not a membrane addressing/anchoring signal
-
Tremblais K, Oliver L, Juin P, Le Cabellec TM, Meflah K, Vallette FM. The C-terminus of bax is not a membrane addressing/anchoring signal. Biochem Biophys Res Commun 1999; 260: 582-591.
-
(1999)
Biochem Biophys Res Commun
, vol.260
, pp. 582-591
-
-
Tremblais, K.1
Oliver, L.2
Juin, P.3
Le Cabellec, T.M.4
Meflah, K.5
Vallette, F.M.6
-
21
-
-
33947409221
-
TOM22, a core component of the mitochondria outer membrane protein translocation pore, is a mitochondrial receptor for the proapoptotic protein Bax
-
Bellot G, Cartron PF, Er E, Oliver L, Juin P, Armstrong LC et al. TOM22, a core component of the mitochondria outer membrane protein translocation pore, is a mitochondrial receptor for the proapoptotic protein Bax. Cell Death Differ 2007; 14: 785-794.
-
(2007)
Cell Death Differ
, vol.14
, pp. 785-794
-
-
Bellot, G.1
Cartron, P.F.2
Er, E.3
Oliver, L.4
Juin, P.5
Armstrong, L.C.6
-
22
-
-
0033522391
-
Conformation of the Bax C-terminus regulates subcellular location and cell death
-
Nechushtan A, Smith CL, Hsu YT, Youle RJ. Conformation of the Bax C-terminus regulates subcellular location and cell death. EMBO J 1999; 18: 2330-2341.
-
(1999)
EMBO J
, vol.18
, pp. 2330-2341
-
-
Nechushtan, A.1
Smith, C.L.2
Hsu, Y.T.3
Youle, R.J.4
-
23
-
-
1842613595
-
Conformational control of Bax localization and apoptotic activity by Pro168
-
Schinzel A, Kaufmann T, Schuler M, Martinalbo J, Grubb D, Bomer C. Conformational control of Bax localization and apoptotic activity by Pro168. J Cell Biol 2004; 164: 1021-1032.
-
(2004)
J Cell Biol
, vol.164
, pp. 1021-1032
-
-
Schinzel, A.1
Kaufmann, T.2
Schuler, M.3
Martinalbo, J.4
Grubb, D.5
Bomer, C.6
-
24
-
-
34247354978
-
The N-terminal conformation of Bax regulates cell commitment to apoptosis
-
Upton JP, Valentijn AJ, Zhang L, Gilmore AP. The N-terminal conformation of Bax regulates cell commitment to apoptosis. Cell Death Differ 2007; 14: 932-942.
-
(2007)
Cell Death Differ
, vol.14
, pp. 932-942
-
-
Upton, J.P.1
Valentijn, A.J.2
Zhang, L.3
Gilmore, A.P.4
-
25
-
-
0033521741
-
Molecular characterization of mitochondrial apoptosis-inducing factor
-
Susin SA, Lorenzo HK, Zamzami N, Marzo I, Snow BE, Brothers GM et al Molecular characterization of mitochondrial apoptosis-inducing factor. Nature 1999; 397: 441-446.
-
(1999)
Nature
, vol.397
, pp. 441-446
-
-
Susin, S.A.1
Lorenzo, H.K.2
Zamzami, N.3
Marzo, I.4
Snow, B.E.5
Brothers, G.M.6
-
26
-
-
33747588097
-
Functional characterization of the Bcl-2 gene family in the zebrafish
-
Kratz E, Eimon PM, Mukhyala K, Stem H, Zha J, Strasser A et al. Functional characterization of the Bcl-2 gene family in the zebrafish. Cell Death Differ 2006; 13: 1631-1640.
-
(2006)
Cell Death Differ
, vol.13
, pp. 1631-1640
-
-
Kratz, E.1
Eimon, P.M.2
Mukhyala, K.3
Stem, H.4
Zha, J.5
Strasser, A.6
-
27
-
-
0028234557
-
Mitochondrial Mas70p signal anchor sequence. Mutations in the transmembrane domain that disrupt dimerization but not targeting or membrane insertion
-
Millar DG, Shore GC. Mitochondrial Mas70p signal anchor sequence. Mutations in the transmembrane domain that disrupt dimerization but not targeting or membrane insertion. J Biol Chem 1994; 269: 12229-12232.
-
(1994)
J Biol Chem
, vol.269
, pp. 12229-12232
-
-
Millar, D.G.1
Shore, G.C.2
-
28
-
-
2942625430
-
Bcl-x(L) sequesters its C-terminal membrane anchor in soluble, cytosolic homodimers
-
Jeong SY, Gaume B, Lee YJ, Hsu YT, Ryu SW, Yoon SH et al. Bcl-x(L) sequesters its C-terminal membrane anchor in soluble, cytosolic homodimers. EMBO J 2004; 23: 2146-2155.
-
(2004)
EMBO J
, vol.23
, pp. 2146-2155
-
-
Jeong, S.Y.1
Gaume, B.2
Lee, Y.J.3
Hsu, Y.T.4
Ryu, S.W.5
Yoon, S.H.6
-
29
-
-
0035844867
-
Bax and Bak coalesce into novel mitochondria-associated clusters during apoptosis
-
Nechushtan A, Smith CL, Lamensdorf I, Yoon SH, Youle RJ. Bax and Bak coalesce into novel mitochondria-associated clusters during apoptosis. J Cell Biol 2001; 153: 1265-1276.
-
(2001)
J Cell Biol
, vol.153
, pp. 1265-1276
-
-
Nechushtan, A.1
Smith, C.L.2
Lamensdorf, I.3
Yoon, S.H.4
Youle, R.J.5
-
30
-
-
0042090307
-
BCL-2 selectively interacts with the BID-induced open conformer of BAK, inhibiting BAK auto-oligomerization
-
Ruffolo SC, Shore GC. BCL-2 selectively interacts with the BID-induced open conformer of BAK, inhibiting BAK auto-oligomerization. J Biol Chem 2003; 278: 25039-25045.
-
(2003)
J Biol Chem
, vol.278
, pp. 25039-25045
-
-
Ruffolo, S.C.1
Shore, G.C.2
-
31
-
-
33744953583
-
Auto-aclivation of the apoptosis protein Bax increases mitochondrial membrane permeability and is inhibited by Bcl-2
-
Tan C, Dlugosz PJ, Peng J, Zhang Z, Lapolla SM, Plafker SM et al. Auto-aclivation of the apoptosis protein Bax increases mitochondrial membrane permeability and is inhibited by Bcl-2. J Biol Chem 2006; 281: 14764-14775.
-
(2006)
J Biol Chem
, vol.281
, pp. 14764-14775
-
-
Tan, C.1
Dlugosz, P.J.2
Peng, J.3
Zhang, Z.4
Lapolla, S.M.5
Plafker, S.M.6
-
32
-
-
34250183921
-
Post-translational integration of tail-anchored proteins is facilitated by defined molecular chaperones
-
Abell BM, Rabu C, Leznicki P, Young JC, High S. Post-translational integration of tail-anchored proteins is facilitated by defined molecular chaperones. J Cell Sci 2007; 120: 1743-1751.
-
(2007)
J Cell Sci
, vol.120
, pp. 1743-1751
-
-
Abell, B.M.1
Rabu, C.2
Leznicki, P.3
Young, J.C.4
High, S.5
-
33
-
-
33947218544
-
Identification of a targeting factor for posttranslational membrane protein insertion into the ER
-
Stefanovic S, Hegde RS. Identification of a targeting factor for posttranslational membrane protein insertion into the ER. Cell 2007; 128: 1147-1159.
-
(2007)
Cell
, vol.128
, pp. 1147-1159
-
-
Stefanovic, S.1
Hegde, R.S.2
-
34
-
-
0033713002
-
Structure of Bax: Coregulation of dimer formation and intracellular localization
-
Suzuki M, Youle RJ, Tjandra N. Structure of Bax: Coregulation of dimer formation and intracellular localization. Cell 2000; 103: 645-654.
-
(2000)
Cell
, vol.103
, pp. 645-654
-
-
Suzuki, M.1
Youle, R.J.2
Tjandra, N.3
-
35
-
-
0036850312
-
Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane
-
Kuwana T, Mackey MR, Perkins G, Ellisman MH, Latterich M, Schneiter R et al. Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane. Cell 2002; 111: 331-342.
-
(2002)
Cell
, vol.111
, pp. 331-342
-
-
Kuwana, T.1
Mackey, M.R.2
Perkins, G.3
Ellisman, M.H.4
Latterich, M.5
Schneiter, R.6
-
36
-
-
0037115740
-
Bax oligomerization in mitochondrial membranes requires tBid (caspase-8-cleaved Bid) and a mitochondrial protein
-
Roucou X, Montessuit S, Antonsson B, Martinou JC. Bax oligomerization in mitochondrial membranes requires tBid (caspase-8-cleaved Bid) and a mitochondrial protein. Biochem J 2002; 368: 915-921.
-
(2002)
Biochem J
, vol.368
, pp. 915-921
-
-
Roucou, X.1
Montessuit, S.2
Antonsson, B.3
Martinou, J.C.4
-
37
-
-
34948850958
-
The mitochondrial TOM complex is required for tBid/Bax-induced cytochrome c release
-
Ott M, Norberg E, Walter KM, Schreiner P, Kemper C, Rapaport D et al The mitochondrial TOM complex is required for tBid/Bax-induced cytochrome c release. J Biol Chem 2007; 282: 27633-27639.
-
(2007)
J Biol Chem
, vol.282
, pp. 27633-27639
-
-
Ott, M.1
Norberg, E.2
Walter, K.M.3
Schreiner, P.4
Kemper, C.5
Rapaport, D.6
-
38
-
-
33947321082
-
Preprotein transport machineries of yeast mitochondrial outer membrane are not required for Bax-induced release of intermembrane space proteins
-
Sanjuan Szldarz LK, Kozjak-Pavlovic V, Vogtle FN, Chacinska A, Milenkovic D, Vogel S et al. Preprotein transport machineries of yeast mitochondrial outer membrane are not required for Bax-induced release of intermembrane space proteins. J Mol Biol 2007; 368 44-54.
-
(2007)
J Mol Biol
, vol.368
, pp. 44-54
-
-
Sanjuan Szldarz, L.K.1
Kozjak-Pavlovic, V.2
Vogtle, F.N.3
Chacinska, A.4
Milenkovic, D.5
Vogel, S.6
-
39
-
-
33845685298
-
Cytosolic factor- and TOM-independent import of C-tail-anchored mitochondrial outer membrane proteins
-
Setoguchi K, Otera H, Mihara K. Cytosolic factor- and TOM-independent import of C-tail-anchored mitochondrial outer membrane proteins. EMBO J 2006; 25: 5635-5647.
-
(2006)
EMBO J
, vol.25
, pp. 5635-5647
-
-
Setoguchi, K.1
Otera, H.2
Mihara, K.3
-
40
-
-
0036668515
-
High throughput two-dimensional blue-native electrophoresis: A tool for functional proteomics of mitochondria and signaling complexes
-
Brookes PS, Pinner A, Ramachandran A, Coward L, Barnes S, Kim H et al High throughput two-dimensional blue-native electrophoresis: A tool for functional proteomics of mitochondria and signaling complexes. Proteomics 2002; 2: 969-977.
-
(2002)
Proteomics
, vol.2
, pp. 969-977
-
-
Brookes, P.S.1
Pinner, A.2
Ramachandran, A.3
Coward, L.4
Barnes, S.5
Kim, H.6
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