Repetitive deformation activates Src-independent FAK-dependent ERK motogenic signals in human Caco-2 intestinal epithelial cells

American Journal of Physiology - Cell Physiology

Volumn 294, Issue 6, 2008, Pages

  Chaturvedi, Lakshmi S ^a,b   Gayer, Christopher P ^a,b   Marsh, Harold M ^a,b   Basson, Marc D ^a,b,c  

^a WAYNE STATE UNIVERSITY   (United States)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Cyclic strain; Intestine; Mechanotransduction; Migration; Signaling

Indexed keywords

FIBRONECTIN; FOCAL ADHESION KINASE; MITOGEN ACTIVATED PROTEIN KINASE; SMALL INTERFERING RNA; 4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; MITOGEN ACTIVATED PROTEIN KINASE 1; PROTEIN KINASE C; PROTEIN KINASE INHIBITOR; PROTEIN TYROSINE KINASE; PYRIMIDINE DERIVATIVE;

ARTICLE; CELL MIGRATION; CELL STRAIN CACO 2; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; INTESTINE EPITHELIUM CELL; MECHANICAL STRESS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; CELL MOTION; CELL SHAPE; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; EPITHELIUM CELL; FOCAL ADHESION; GASTROINTESTINAL MOTILITY; GENETIC TRANSFECTION; GENETICS; INTESTINE MUCOSA; MECHANOTRANSDUCTION; METABOLISM; MUTATION; PATHOLOGY; PHOSPHORYLATION; RNA INTERFERENCE; TIME; WOUND HEALING;

CACO-2 CELLS; CELL MOVEMENT; CELL SHAPE; ENZYME ACTIVATION; EPITHELIAL CELLS; FIBRONECTINS; FOCAL ADHESION PROTEIN-TYROSINE KINASES; FOCAL ADHESIONS; GASTROINTESTINAL MOTILITY; HUMANS; INTESTINAL MUCOSA; MECHANOTRANSDUCTION, CELLULAR; MITOGEN-ACTIVATED PROTEIN KINASE 1; MUTATION; PHOSPHORYLATION; PROTEIN KINASE C; PROTEIN KINASE INHIBITORS; PYRIMIDINES; RNA INTERFERENCE; SRC-FAMILY KINASES; STRESS, MECHANICAL; TIME FACTORS; TRANSFECTION; WOUND HEALING;

EID: 47249093328     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00027.2008     Document Type: Article

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