-
1
-
-
19344364880
-
Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: An overview of the randomised trials
-
Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials. Lancet 365(9472), 1687-1717 (2005).
-
(2005)
Lancet
, vol.365
, Issue.9472
, pp. 1687-1717
-
-
-
2
-
-
0037301972
-
Survival of patients with metastatic breast carcinoma: Importance of prognostic markers of the primary tumor
-
Chang J, Clark GM, Allred DC, Mohsin S, Chamness G, Elledge RM: Survival of patients with metastatic breast carcinoma: importance of prognostic markers of the primary tumor. Cancer 97(3), 545-553 (2003).
-
(2003)
Cancer
, vol.97
, Issue.3
, pp. 545-553
-
-
Chang, J.1
Clark, G.M.2
Allred, D.C.3
Mohsin, S.4
Chamness, G.5
Elledge, R.M.6
-
3
-
-
0023145358
-
Survival from first recurrence: Relative importance of prognostic factors in 1,015 breast cancer patients
-
Clark GM, Sledge GW Jr, Osborne CK, McGuire WL: Survival from first recurrence: relative importance of prognostic factors in 1,015 breast cancer patients. J. Clin. Oncol. 5(1), 55-61 (1987).
-
(1987)
J. Clin. Oncol
, vol.5
, Issue.1
, pp. 55-61
-
-
Clark, G.M.1
Sledge Jr, G.W.2
Osborne, C.K.3
McGuire, W.L.4
-
4
-
-
0032949449
-
Prospective randomized trial of docetaxel versus mitomycin plus vinblastine in patients with metastatic breast cancer progressing despite previous andiracycline-containing chemotherapy. 304 Study Group
-
Nabholtz JM, Senn HJ, Bewoda WR et al.: Prospective randomized trial of docetaxel versus mitomycin plus vinblastine in patients with metastatic breast cancer progressing despite previous andiracycline-containing chemotherapy. 304 Study Group. J. Clin. Oncol. 17(5), 1413-1424 (1999).
-
(1999)
J. Clin. Oncol
, vol.17
, Issue.5
, pp. 1413-1424
-
-
Nabholtz, J.M.1
Senn, H.J.2
Bewoda, W.R.3
-
5
-
-
0032809977
-
Initial paclitaxel improves outcome compared with CMFP combination chemotherapy as frontline therapy in untreated metastatic breast cancer
-
Bishop JF, Dewar J, Toner GC et al.: Initial paclitaxel improves outcome compared with CMFP combination chemotherapy as frontline therapy in untreated metastatic breast cancer. J. Clin. Oncol. 17 (8), 2355-2364 (1999).
-
(1999)
J. Clin. Oncol
, vol.17
, Issue.8
, pp. 2355-2364
-
-
Bishop, J.F.1
Dewar, J.2
Toner, G.C.3
-
6
-
-
0037441856
-
Phase III trial of doxorubicin, paclitaxel, and the combination of doxorubicin and paclitaxel as front-line chemotherapy for metastatic breast cancer: An intergroup trial (EI 193)
-
Sledge GW, Neuberg D, Bernardo P et al.: Phase III trial of doxorubicin, paclitaxel, and the combination of doxorubicin and paclitaxel as front-line chemotherapy for metastatic breast cancer: an intergroup trial (EI 193). J. Clin. Oncol. 21(4), 588-592 (2003).
-
(2003)
J. Clin. Oncol
, vol.21
, Issue.4
, pp. 588-592
-
-
Sledge, G.W.1
Neuberg, D.2
Bernardo, P.3
-
7
-
-
0032787785
-
Prospective randomized trial of docetaxel versus doxorubicin in patients with metastatic breast cancer
-
Chan S, Friedrichs K, Noel D et al.: Prospective randomized trial of docetaxel versus doxorubicin in patients with metastatic breast cancer. J. Clin. Oncol. 17(8), 2341-2354 (1999).
-
(1999)
J. Clin. Oncol
, vol.17
, Issue.8
, pp. 2341-2354
-
-
Chan, S.1
Friedrichs, K.2
Noel, D.3
-
8
-
-
24944507764
-
Randomized Phase III study of docetaxel compared with paclitaxel in metastatic breast cancer
-
Jones SE, Erban J, Overmoyer B et al.: Randomized Phase III study of docetaxel compared with paclitaxel in metastatic breast cancer. J. Clin. Oncol. 23(24), 5542-5551 (2005).
-
(2005)
J. Clin. Oncol
, vol.23
, Issue.24
, pp. 5542-5551
-
-
Jones, S.E.1
Erban, J.2
Overmoyer, B.3
-
9
-
-
32944482677
-
Superior efficacy of albumin-bound paclitaxel, ABI-007, compared with polyethylated castor oil-based paclitaxel in women with metastatic breast cancer: Results of a Phase III trial
-
Gradishar WJ, Tjulandin S, Davidson N et al.: Superior efficacy of albumin-bound paclitaxel, ABI-007, compared with polyethylated castor oil-based paclitaxel in women with metastatic breast cancer: results of a Phase III trial. J. Clin. Oncol. 23 (31), 7794-7803 (2005).
-
(2005)
J. Clin. Oncol
, vol.23
, Issue.31
, pp. 7794-7803
-
-
Gradishar, W.J.1
Tjulandin, S.2
Davidson, N.3
-
10
-
-
47249118093
-
-
O'Shaughnessy J, Nag S, Calderill-Ruiz G et al.: Gemcitabine plus paclitaxel (GT) versus paclitaxel (T) as first-line treatment for anthracycline pre-treated metastatic breast cancer (MBC), interim results of a global Phase III study. Proc. Am. Soc. Clin. Oncol. 22(7) (2003) (Abstract 25).
-
O'Shaughnessy J, Nag S, Calderill-Ruiz G et al.: Gemcitabine plus paclitaxel (GT) versus paclitaxel (T) as first-line treatment for anthracycline pre-treated metastatic breast cancer (MBC), interim results of a global Phase III study. Proc. Am. Soc. Clin. Oncol. 22(7) (2003) (Abstract 25).
-
-
-
-
11
-
-
17344390083
-
Docetaxel compared with sequential methotrexate and 5-fluorouracil in patients with advanced breast cancer after anthracycline failure: A randomised Phase III study wito crossover on progression by the Scandinavian Breast Group
-
Sjostrom J, Blomqvist C, Mouridsen H et al.: Docetaxel compared with sequential methotrexate and 5-fluorouracil in patients with advanced breast cancer after anthracycline failure: a randomised Phase III study wito crossover on progression by the Scandinavian Breast Group. Eur. J. Cancer 35(8), 1194-1201 (1999).
-
(1999)
Eur. J. Cancer
, vol.35
, Issue.8
, pp. 1194-1201
-
-
Sjostrom, J.1
Blomqvist, C.2
Mouridsen, H.3
-
12
-
-
0037096755
-
Superior survival with capecitabine plus docetaxel combination therapy in anthracycline-pretreated patients with advanced breast cancer: Phase III trial results
-
O'Shaughnessy J, Miles D, Vukelja S et al.: Superior survival with capecitabine plus docetaxel combination therapy in anthracycline-pretreated patients with advanced breast cancer: Phase III trial results. J. Clin. Oncol. 20(12), 2812-2823 (2002).
-
(2002)
J. Clin. Oncol
, vol.20
, Issue.12
, pp. 2812-2823
-
-
O'Shaughnessy, J.1
Miles, D.2
Vukelja, S.3
-
13
-
-
0037132372
-
Docetaxel vs 5-fluorouracil plus vinorelbine in metastatic breast cancer after anthracycline therapy failure
-
Bonneterre J, Roche H, Monnier A et al.: Docetaxel vs 5-fluorouracil plus vinorelbine in metastatic breast cancer after anthracycline therapy failure. Br. J. Cancer 87(11), 1210-1215 (2002).
-
(2002)
Br. J. Cancer
, vol.87
, Issue.11
, pp. 1210-1215
-
-
Bonneterre, J.1
Roche, H.2
Monnier, A.3
-
14
-
-
0036909220
-
Single-agent capecitabine: A reference treatment for taxane-pretreated metastatic breast cancer?
-
Seidman AD, O'Shaughnessy J, Misset JL: Single-agent capecitabine: a reference treatment for taxane-pretreated metastatic breast cancer? Oncologist 7 (Suppl. 6), 20-28 (2002).
-
(2002)
Oncologist
, vol.7
, Issue.SUPPL. 6
, pp. 20-28
-
-
Seidman, A.D.1
O'Shaughnessy, J.2
Misset, J.L.3
-
15
-
-
18444417397
-
Randomised, Phase II trial comparing oral capecitabine (Xeloda) with paclitaxel in patients with metastatic/advanced breast cancer pretreated with anthracyclines
-
Talbot DC, Moiseyenko V, van Belle S et al.: Randomised, Phase II trial comparing oral capecitabine (Xeloda) with paclitaxel in patients with metastatic/advanced breast cancer pretreated with anthracyclines. Br. J. Cancer 86(9), 1367-1372 (2002).
-
(2002)
Br. J. Cancer
, vol.86
, Issue.9
, pp. 1367-1372
-
-
Talbot, D.C.1
Moiseyenko, V.2
van Belle, S.3
-
17
-
-
33745262072
-
Epothilones in the treatment of cancer
-
Larkin JM, Kaye SB: Epothilones in the treatment of cancer. Expert Opin. Invest. Drugs 15(6), 691-702 (2006).
-
(2006)
Expert Opin. Invest. Drugs
, vol.15
, Issue.6
, pp. 691-702
-
-
Larkin, J.M.1
Kaye, S.B.2
-
18
-
-
0029802685
-
The microtubule-affecting drug paclitaxel has antiangiogenic activity
-
Belotti D, Vergani V, Drudis T et al.: The microtubule-affecting drug paclitaxel has antiangiogenic activity. Clin. Cancer Res. 2(11), 1843-1849 (1996).
-
(1996)
Clin. Cancer Res
, vol.2
, Issue.11
, pp. 1843-1849
-
-
Belotti, D.1
Vergani, V.2
Drudis, T.3
-
19
-
-
0035756986
-
Chemistry and chemical biology of taxane anticancer agents
-
Miller ML, Ojima I: Chemistry and chemical biology of taxane anticancer agents. Chem. Rec. 1(3), 195-211 (2001).
-
(2001)
Chem. Rec
, vol.1
, Issue.3
, pp. 195-211
-
-
Miller, M.L.1
Ojima, I.2
-
20
-
-
33644977169
-
Paclitaxel-resistant cells have a mutation in the paclitaxel-binding region of β-tubulin (Asp26Glu) and less stable microtubules
-
Had M, Loganzo F, Annable T et al.: Paclitaxel-resistant cells have a mutation in the paclitaxel-binding region of β-tubulin (Asp26Glu) and less stable microtubules. Mol. Cancer Ther. 5(2), 270-278 (2006).
-
(2006)
Mol. Cancer Ther
, vol.5
, Issue.2
, pp. 270-278
-
-
Had, M.1
Loganzo, F.2
Annable, T.3
-
21
-
-
3843053396
-
The binding mode of epothilone A on α, β-tubulin by electron crystallography
-
Nettles JH, Li H, Cornett B, Krahn JM, Snyder JP, Downing KH: The binding mode of epothilone A on α, β-tubulin by electron crystallography. Science 305(5685), 866-869 (2004).
-
(2004)
Science
, vol.305
, Issue.5685
, pp. 866-869
-
-
Nettles, J.H.1
Li, H.2
Cornett, B.3
Krahn, J.M.4
Snyder, J.P.5
Downing, K.H.6
-
22
-
-
0034895987
-
BMS-247550: A novel epothilone analog with a mode of action similar to paclitaxel but possessing superior antitumor efficacy
-
Lee FY, Borzilleri R, Fairchild CR et al.: BMS-247550: a novel epothilone analog with a mode of action similar to paclitaxel but possessing superior antitumor efficacy. Clin. Cancer Res. 7(5), 1429-1437 (2001).
-
(2001)
Clin. Cancer Res
, vol.7
, Issue.5
, pp. 1429-1437
-
-
Lee, F.Y.1
Borzilleri, R.2
Fairchild, C.R.3
-
23
-
-
0029049468
-
Epothilones, a new class of microtubule-stabilizing agents with a taxol-like mechanism of action
-
Bollag DM, McQueney PA, Zhu J et al.: Epothilones, a new class of microtubule-stabilizing agents with a taxol-like mechanism of action. Cancer Res. 55(11), 2325-2333 (1995).
-
(1995)
Cancer Res
, vol.55
, Issue.11
, pp. 2325-2333
-
-
Bollag, D.M.1
McQueney, P.A.2
Zhu, J.3
-
24
-
-
34047212584
-
Phase I study of the novel epothilone analog ixabepilone (BMS-247550) in patients with advanced solid tumors and lymphomas
-
Aghajanian C, Burris HA 3rd, Jones S et al.: Phase I study of the novel epothilone analog ixabepilone (BMS-247550) in patients with advanced solid tumors and lymphomas. J. Clin. Oncol. 25(9), 1082-1088 (2007).
-
(2007)
J. Clin. Oncol
, vol.25
, Issue.9
, pp. 1082-1088
-
-
Aghajanian, C.1
Burris 3rd, H.A.2
Jones, S.3
-
25
-
-
12144285977
-
Phase I clinical and pharmacokinetic study of BMS-247550, a novel derivative of epothilone B, in solid tumors
-
Mani S, McDaid H, Hamilton A et al.: Phase I clinical and pharmacokinetic study of BMS-247550, a novel derivative of epothilone B, in solid tumors. Clin. Cancer Res. 10(4), 1289-1298 (2004).
-
(2004)
Clin. Cancer Res
, vol.10
, Issue.4
, pp. 1289-1298
-
-
Mani, S.1
McDaid, H.2
Hamilton, A.3
-
26
-
-
24344450233
-
Phase I clinical trial of BMS-247550, a derivative of epothilone B, using accelerated titration 2B design
-
Gadgeel SM, Wozniak A, Boinpally RR et al.: Phase I clinical trial of BMS-247550, a derivative of epothilone B, using accelerated titration 2B design. Clin. Cancer Res. 11(17), 6233-6239 (2005).
-
(2005)
Clin. Cancer Res
, vol.11
, Issue.17
, pp. 6233-6239
-
-
Gadgeel, S.M.1
Wozniak, A.2
Boinpally, R.R.3
-
27
-
-
20244376916
-
A Phase I clinical trial of ixabepilone (BMS-247550), an epothilone B analog, administered intravenously on a daily schedule for 3 days
-
Zhuang SH, Agrawal M, Edgerly M et al.: A Phase I clinical trial of ixabepilone (BMS-247550), an epothilone B analog, administered intravenously on a daily schedule for 3 days. Cancer 103(9), 1932-1938 (2005).
-
(2005)
Cancer
, vol.103
, Issue.9
, pp. 1932-1938
-
-
Zhuang, S.H.1
Agrawal, M.2
Edgerly, M.3
-
28
-
-
0038811741
-
Phase I trial and pharmacokinetic study of BMS-247550, an epothilone B analog, administered intravenously on a daily schedule for five days
-
Abraham J, Agrawai M, Bakke S et al.: Phase I trial and pharmacokinetic study of BMS-247550, an epothilone B analog, administered intravenously on a daily schedule for five days. J. Clin. Oncol. 21(9), 1866-1873 (2003).
-
(2003)
J. Clin. Oncol
, vol.21
, Issue.9
, pp. 1866-1873
-
-
Abraham, J.1
Agrawai, M.2
Bakke, S.3
-
29
-
-
34248183039
-
Ixabepilone given weekly in patients with advanced malignancies: Final efficacy and safety results of a Phase I trial
-
Abstract 2040
-
Dickson N, Peck R, Wu C, Burris H: Ixabepilone given weekly in patients with advanced malignancies: final efficacy and safety results of a Phase I trial. J. Clin. Oncol. 24(S18) (2006) (Abstract 2040).
-
(2006)
J. Clin. Oncol
, Issue.S18
, pp. 24
-
-
Dickson, N.1
Peck, R.2
Wu, C.3
Burris, H.4
-
30
-
-
47249094258
-
A Phase I pharmacokinetic (PK) study of the epothilone B analogue, ixabepilone (BMS-247550) in patients (pts) with advanced malignancies and varying degrees of hepatic impairment. A SWOG Early Therapeutics Commitee and NCI Organ Dysfunction Working Group Trial
-
Abstract
-
Takimoto CH, Liu PY, Lenz H et al.: A Phase I pharmacokinetic (PK) study of the epothilone B analogue, ixabepilone (BMS-247550) in patients (pts) with advanced malignancies and varying degrees of hepatic impairment. A SWOG Early Therapeutics Commitee and NCI Organ Dysfunction Working Group Trial. J. Clin. Oncol. 24(S18) (2006) (Abstract 2004).
-
(2004)
J. Clin. Oncol
, Issue.S18
, pp. 24
-
-
Takimoto, C.H.1
Liu, P.Y.2
Lenz, H.3
-
31
-
-
34548157209
-
Efficacy and safety of ixabepilone (BMS-247550) in a Phase II study of patients with advanced breast cancer resistant to an anthracycline, a taxane, and capecitabine
-
Perez EA, Lerzo G, Pivot X et al.: Efficacy and safety of ixabepilone (BMS-247550) in a Phase II study of patients with advanced breast cancer resistant to an anthracycline, a taxane, and capecitabine. J. Clin. Oncol. 25(23), 3407-3414 (2007).
-
(2007)
J. Clin. Oncol
, vol.25
, Issue.23
, pp. 3407-3414
-
-
Perez, E.A.1
Lerzo, G.2
Pivot, X.3
-
32
-
-
34548187738
-
Phase II clinical trial of ixabepilone (BMS-247550), an epothilone B analog, in patients with taxane-resistant metastatic breast cancer
-
Thomas E, Tabernero J, Fornier M et al.: Phase II clinical trial of ixabepilone (BMS-247550), an epothilone B analog, in patients with taxane-resistant metastatic breast cancer. J. Clin. Oncol. 25(23), 3399-3406 (2007).
-
(2007)
J. Clin. Oncol
, vol.25
, Issue.23
, pp. 3399-3406
-
-
Thomas, E.1
Tabernero, J.2
Fornier, M.3
-
33
-
-
21044441003
-
Phase II clinical trial of ixabepilone (BMS-247550), an epothilone B analog, in metastatic and locally advanced breast cancer
-
Low JA, Wedam SB, Lee JJ et al.: Phase II clinical trial of ixabepilone (BMS-247550), an epothilone B analog, in metastatic and locally advanced breast cancer. J. Clin. Oncol. 23(12), 2726-2734 (2005).
-
(2005)
J. Clin. Oncol
, vol.23
, Issue.12
, pp. 2726-2734
-
-
Low, J.A.1
Wedam, S.B.2
Lee, J.J.3
-
34
-
-
34548179878
-
Phase II clinical trial of ixabepilone (BMS-247550), an epothilone B analog, as first-line therapy in patients with metastatic breast cancer previously treated with anthracycline chemotherapy
-
Roche H, Yelle L, Cognetti F et al.: Phase II clinical trial of ixabepilone (BMS-247550), an epothilone B analog, as first-line therapy in patients with metastatic breast cancer previously treated with anthracycline chemotherapy. J. Clin. Oncol. 25(23), 3415-3420 (2007).
-
(2007)
J. Clin. Oncol
, vol.25
, Issue.23
, pp. 3415-3420
-
-
Roche, H.1
Yelle, L.2
Cognetti, F.3
-
35
-
-
34548169630
-
Phase II trial of ixabepilone, an epothilone B analog, in patients with metastatic breast cancer previously untreated with taxanes
-
Denduluri N, Low JA, Lee JJ et al.: Phase II trial of ixabepilone, an epothilone B analog, in patients with metastatic breast cancer previously untreated with taxanes. J. Clin. Oncol. 25(23), 3421-3427 (2007).
-
(2007)
J. Clin. Oncol
, vol.25
, Issue.23
, pp. 3421-3427
-
-
Denduluri, N.1
Low, J.A.2
Lee, J.J.3
-
36
-
-
34247161458
-
Predicting response to ixabepilone: Genomics study in patients receiving single agent ixabepilone as neoadjuvant treatment for breast cancer (BC)
-
Presented at:, San Antonio, TX, USA, 8-11 December, Abstract 305
-
Baselga J, Gianni L, Llombart A et al.: Predicting response to ixabepilone: genomics study in patients receiving single agent ixabepilone as neoadjuvant treatment for breast cancer (BC). Presented at: San Antonio Breast Cancer Symposium. San Antonio, TX, USA, 8-11 December 2005 (Abstract 305).
-
(2005)
San Antonio Breast Cancer Symposium
-
-
Baselga, J.1
Gianni, L.2
Llombart, A.3
-
37
-
-
34247848547
-
Final efficacy results of a Phase I/II trial of ixabepilone in combination with capecitabine in patients with metastatic breast cancer (MBC) previously treated with a taxane and anthracycline
-
Abstract 10511
-
Bunnell C, Klimovsky J, Thomas E: Final efficacy results of a Phase I/II trial of ixabepilone in combination with capecitabine in patients with metastatic breast cancer (MBC) previously treated with a taxane and anthracycline. J. Clin. Oncol. 24(S18) (2006) (Abstract 10511).
-
(2006)
J. Clin. Oncol
, Issue.S18
, pp. 24
-
-
Bunnell, C.1
Klimovsky, J.2
Thomas, E.3
-
38
-
-
36849071808
-
Ixabepilone plus capecitabine for metastatic breast cancer progressing after anthracycline and taxane treatment
-
Thomas ES, Gomez HL, Li RK et al.: Ixabepilone plus capecitabine for metastatic breast cancer progressing after anthracycline and taxane treatment. J. Clin. Oncol. 25(33), 5210-5217 (2007).
-
(2007)
J. Clin. Oncol
, vol.25
, Issue.33
, pp. 5210-5217
-
-
Thomas, E.S.1
Gomez, H.L.2
Li, R.K.3
-
39
-
-
84928590219
-
+) metastatic breast cancer (MBC). A trial coordinated by the Eastern Cooperative Oncology Group (E2103)
-
Atlanta, GA, USA, 2-6 June, Abstract 152
-
+) metastatic breast cancer (MBC). A trial coordinated by the Eastern Cooperative Oncology Group (E2103). 42nd ASCO Annual Meeting. Atlanta, GA, USA, 2-6 June, 2006 (Abstract 152).
-
(2006)
42nd ASCO Annual Meeting
-
-
Moulder, S.L.1
Wang, M.2
Gradishar3
|