Effects of cycloheximide on extinction in an appetitively motivated operant conditioning task depend on re-exposure duration

Neuroscience Letters

Volumn 441, Issue 3, 2008, Pages 307-310

  Mierzejewski, Pawel ^a   Olczak, Mieszko ^a   Rogowski, Artur ^a   Kostowski, Wojciech ^a   Samochowiec, Jerzy ^b   Filip, Malgorzata ^c   Przegalinski, Edmund ^c   Bienkowski, Przemyslaw ^a  

^a INSTITUTE OF PSYCHIATRY AND NEUROLOGY   (Poland)

^b POMERANIAN MEDICAL UNIVERSITY   (Poland)

^c INSTITUTE OF PHARMACOLOGY   (Poland)

Author keywords

Cycloheximide; De novo protein synthesis; Extinction; Relapse; Saccharin self administration

Indexed keywords

CYCLOHEXIMIDE; SACCHARIN;

ADDICTION; ANIMAL EXPERIMENT; APPETITE; ARTICLE; ASSOCIATION; CONTROLLED STUDY; DRUG EFFECT; INSTRUMENTAL CONDITIONING; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RAT; REINFORCEMENT; REWARD; TASK PERFORMANCE;

ANIMALS; APPETITIVE BEHAVIOR; CONDITIONING, OPERANT; CUES; CYCLOHEXIMIDE; EXTINCTION, PSYCHOLOGICAL; MALE; MOTIVATION; NERVE TISSUE PROTEINS; PROTEIN SYNTHESIS INHIBITORS; RATS; RATS, WISTAR; RECURRENCE; REINFORCEMENT (PSYCHOLOGY); REWARD; SACCHARIN; SUBSTANCE-RELATED DISORDERS; TIME FACTORS;

EID: 47249085515     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2008.06.047     Document Type: Article

References (21)

1. Barraco R.A., and Stettner L.J. Antibiotics and memory. Psychol. Bull. 83 (1976) 243-302
2. Bienkowski P., Koros E., Kostowski W., and Bogucka-Bonikowska A. Reinstatement of ethanol seeking in rats: behavioral analysis. Pharmacol. Biochem. Behav. 66 (2000) 123-128
3. Bouton M.E. Context, ambiguity, and unlearning: sources of relapse after behavioral extinction. Biol. Psychiatry 52 (2002) 976-986
4. Carroll M.E., Lac S.T., Ascencio M., and Kragh R. Intravenous cocaine self-administration in rats is reduced by dietary l-tryptophan. Psychopharmacology 100 (1990) 293-300
5. Davis H.P., and Squire L.R. Protein synthesis and memory a review. Psychol. Bull. 96 (1984) 518-559
6. Dudai Y. The neurobiology of consolidations, or, how stable is the engram?. Annu. Rev. Psychol. 55 (2004) 51-86
7. Gosnell B.A., and Patel C.K. Centrally administered mu- and delta-opioid agonists increase operant responding for saccharin. Pharmacol. Biochem. Behav. 45 (1993) 979-982
8. Lin C.-H., Yeh S.-H., Lu H.-Y., and Gean P.-W. The similarities and diversities of signal pathways leading to consolidation of conditioning and consolidation of extinction of fear memory. J. Neurosci. 23 (2003) 8310-8317
9. Mierzejewski P., Siemiatkowski M., Radwanska K., Szyndler J., Bienkowski P., Stefanski R., Kaczmarek L., and Kostowski W. Cycloheximide impairs acquisition but not extinction of cocaine self-administration. Neuropharmacology 51 (2006) 367-373
10. Nader K. Memory traces unbound. Trends Neurosci. 26 (2003) 65-72
11. Pedreira M.E., and Maldonado H. Protein synthesis subserves reconsolidation or extinction depending on reminder duration. Neuron 38 (2003) 863-869
12. Power A.E., Berlau D.J., McGaugh J.L., and Steward O. Anisomycin infused into the hippocampus fails to block "reconsolidation" but impairs extinction: the role of re-exposure duration. Learn. Mem. 13 (2006) 27-34
13. Quinton E., and Kramarcy N.R. Memory impairment correlates closely with cycloheximide dose and degree of inhibition of protein synthesis. Brain Res. 131 (1977) 184-190
14. Radwanska K., Wrobel E., Korkosz A., Rogowski A., Kostowski W., Bienkowski P., and Kaczmarek L. Alcohol relapse induced by discrete cues activates components of AP-1 transcription factor and ERK pathway in the rat basolateral and central 337 amygdala. Neuropsychopharmacology. 33 (2008) 1835-1846
15. Sanberg P.R., Faulks I.J., Anson J.M., and Mark R.F. Operant, open-field and tonic immobility behaviours in chickens with forebrain injections of cycloheximide or glutamate. Behav. Brain. Res. 4 (1982) 19-32
16. Santini E., Ge H., Ren K., Peña de Ortiz S., and Quirk G.J. Consolidation of fear extinction requires protein synthesis in the medial prefrontal cortex. J. Neurosci. 24 (2004) 5704-5710
17. Sara S.J. Retrieval and reconsolidation: toward a neurobiology of remembering. Learn. Mem. 7 (2000) 73-84
18. Schweri M.M., and Carr L.A. The effects of Cycloheximide and Anisomycin on monoamine synthesis in a brain synaptosome preparation. J. Neural. Transm. 54 (1982) 41-50
19. Shaham Y., Shalev U., Lu L., De Wit H., and Stewart J. The reinstatement model of drug relapse: history, methodology and major findings. Psychopharmacology 168 (2003) 3-20
20. Suzuki A., Josselyn S.A., Frankland P.W., Masushige S., Silva A.J., and Kida S. Memory reconsolidation and extinction have distinct temporal and biochemical signatures. J. Neurosci. 24 (2004) 4787-4795
21. Vianna M.R., Szapiro G., McGaugh J.L., Medina J.H., and Izquierdo I. Retrieval of memory for fear-motivated training initiates extinction requiring protein synthesis in the rat hippocampus. Proc. Natl. Acad. Sci. U.S.A. 98 (2001) 12251-12254