Preparation of esomeprazole zinc solid dispersion and study on its pharmacokinetics

International Journal of Pharmaceutics

Volumn 360, Issue 1-2, 2008, Pages 53-57

  Xie, Yongmei ^a   Xie, Ping ^b   Song, Xin ^c   Tang, Xiaohai ^a,c,d   Song, Hang ^a  

^a SICHUAN UNIVERSITY   (China)

^b SICHUAN UNIVERSITY   (China)

^c Ychat Bio technology (Chengdu) Co Ltd   (China)

^d SICHUAN CANCER HOSPITAL   (China)

Author keywords

Dissolution rate; Esomeprazole zinc; Pharmacokinetics; Polyethylene glycol; Solid dispersion

Indexed keywords

ESOMEPRAZOLE; ESOMEPRAZOLE ZINC; MACROGOL 4000;

ADULT; ARTICLE; CLINICAL ARTICLE; DIFFERENTIAL SCANNING CALORIMETRY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG CAPSULE; DRUG SOLUBILITY; ENTERIC COATED TABLET; FEMALE; HUMAN; HUMAN EXPERIMENT; IN VIVO STUDY; MALE; NORMAL HUMAN; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY;

ADULT; ANIMALS; CALORIMETRY, DIFFERENTIAL SCANNING; CAPSULES; CHEMISTRY, PHYSICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FEMALE; HUMANS; MALE; MICROSCOPY, ELECTRON, SCANNING; OMEPRAZOLE; POLYETHYLENE GLYCOLS; PROTON PUMP INHIBITORS; RABBITS; SOLUBILITY; TABLETS, ENTERIC-COATED; ZINC;

EID: 47049108297     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2008.04.015     Document Type: Article

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