Myocyte-specific M-CAT and MEF-1 elements regulate G-protein gamma 3 gene (γ3) expression in cardiac myocytes

DNA and Cell Biology

Volumn 27, Issue 7, 2008, Pages 367-376

  McWhinney, Charlene ^a   Robishaw, Janet D ^b  

^a NEW YORK INSTITUTE OF TECHNOLOGY   (United States)

^b WEIS CENTER FOR RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN GAMMA SUBUNIT; GUANINE NUCLEOTIDE BINDING PROTEIN GAMMA SUBUNIT 3; LUCIFERASE; M CAT PROTEIN; MYOCYTE ENHANCER FACTOR 1; PROTEIN; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; CONSENSUS SEQUENCE; CONTROLLED STUDY; GENE CONSTRUCT; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; HEART MUSCLE CELL; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; RAT; REPORTER GENE;

ANIMALS; ANIMALS, NEWBORN; CELLS, CULTURED; GENE EXPRESSION REGULATION; GTP-BINDING PROTEIN GAMMA SUBUNITS; MICE; MODELS, BIOLOGICAL; MYOCYTES, CARDIAC; MYOGENIC REGULATORY FACTORS; ORGAN SPECIFICITY; RATS; RATS, SPRAGUE-DAWLEY; REGULATORY ELEMENTS, TRANSCRIPTIONAL; SWISS 3T3 CELLS; TRANSFECTION;

MUS; RATTUS;

EID: 47049101181     PISSN: 10445498     EISSN: None     Source Type: Journal    
DOI: 10.1089/dna.2008.0754     Document Type: Article

References (49)

1. Amacher, S., Buskin, J., and Hauschka, S.D. (1993). Multiple regulatory elements contribute differentially to muscle creatine kinase enhancer activity in skeletal and cardiac muscle. Mol Cell Biol 13(5), 2753-2764.
2. Apone, S., and Hauschka, S.D. (1995). Muscle gene E-box control elements. J Biol Chem 270(36), 21420-21427.
3. Bell, B., Xing, H., Yan, K., Gautam, N., and Muslin, J. (1999). KSR-1 binds G-protein betagamma subunits and inhibits beta-gamma-induced mitogen-activated protein kinase activation. J Biol Chem 274(12), 7982-7986.
4. Berberich, C., Durr, I., Koenen, M., and Witzemann, V. (1993). Two-adjacent E-box elements and a M-CAT box are involved in muscle-specific- regulation (MSR) of the rat acetylcholine receptor beta subunit gene. Eur J Biochem 216(2), 395-404.
5. Biesiada, E., Hamaori, Y., Kedes, L., and Satorelli, V. (1999). Myogenic basic helix-loop-helix proteins and Sp1 interact as components of a multiprotein transcriptional complex required for activity of the human cardiac alpha-actin promoter. Mol Cell Biol 19(4), 2577-2584.
6. Birnbaumer, L. (1992). Receptor-to-effector signaling through G-proteins: roles for beta gamma dimmers as well as alpha subunits. Cell 71, 1069-1072.
7. Buskin, J.N., and Hauschka, S.D. (1989). Identification of a myocyte nuclear factor that binds to the muscle-specific enhancer of the mouse muscle creatine kinase gene. Mol Cell Biol 9(6), 2627-2640.
8. Butler, A.J., and Ordahl, C.P. (1999). Poly(ADP-Ribose) Polymerase binds with transcription enhancer factor 1 to MCAT1 elements to regulate muscle-specific transcription. Mol Cell Biol 19(1), 296-306.
9. Catala, F., Wanner, R., Barton, P., Cohen, A., Wright, W., and Buckingham, M. (1995). A skeletal muscle-specific enhancer regulated by factors binding to E and CArG boxes is present in the promoter of the mouse myosin light-chain 1A gene. Mol Cell Biol 15(8), 4585-4596.
10. Christensen, T., Prentice, H., Gahlmann, R., and Kedes, L. (1993). Regulation of the human cardiac/slow-twitch troponin C gene by multiple, cooperative, cell-type-specific and MyoD-responsive elements. Mol Cell Biol 13(11), 6752-6765.
11. Clapham, D.E., and Neer, E.J. (1997). G-protein βγ subunits. Annu Rev Pharmacol Toxicol 37, 167-203.
12. Downes, G., Copeland, N., Jenkins, N., and Gautam, N. (1998). Structure and mapping of the G-protein gamma3 subunit gene and a divergently transcribed novel gene, gng31g. Genomics 53(2), 220-230.
13. Du, J., Nan, C., Huang, J., Zhang, C., Liu, J., Jia, P., Abers, M., and Huang, X. (2008). Functional characterization of mouse fetal TnI gene promoters in myocardial cells. J Biomed Sci, epub March 2008.
14. Dubeykovskiy, A., Mcwhinney, C., and Robishaw, J.D. (2007). RUNX-dependent regulation of G-protein Gamma3 expression in T-Cells. Cell Immunol 240, 86-95.
15. Feo, S., Antona, V., Barbieri, G., Passantino, R., Cali, L., and Giallongo, A. (1995). Transcription of the human beta enolase gene (ENO-3) is regulated by an intronic muscle-specific enhancer that binds myocyte-specific enhancer factor 2 proteins and ubiquitous G-rich-box binding factors. Mol Cell Biol 15(11), 5991-6002.
16. Flink, I., Edwards, J., Bahl, J., Liew, C., Sole, M., and Morkin, E. (1992). Characterization of a strong positive cis-acting element of the human beta-myosin heavy chain gene in fetal rat heart cells. J Biol Chem 267(14), 9917-9924.
17. Funamoto, M., Hishinuma, S., Fujio, Y., Matsuda, Y., Kunisada, K., Oh, H., Negoro, S., Tone, E., Kishimoto, T., and Yamauchi-Takihara, K. (2000). Isolation and characterization of the murine cardiotrophin-1 gene: expression and norepinephrine-induced transcriptional activation. J Mol Cell Cardiol 32(7), 1275-1284.
18. Giger, J., Haddad, F., Qin, Z., and Baldwin, K. (2002). Functional overload increases beta-MHC promoter activity in rodent fast muscle via the proximal M-CAT. Am J Physiol Cell Physiol 282(3), C518-C527.
19. Gilman, A.G. (1987). G-proteins: transducers of receptor-generated signals. Annu Rev Biochem 56, 615-649.
20. Gupta, M.P., Gupta, M., and Zak, R. (1994). An E-Box/M-CAT hybrid motif and cognate binding protein(s) regulate the basal muscle-specific and cAMP-inducible expression of the rat cardiac alpha-myosin heavy chain gene. J Biol Chem 269(47), 29677-29687.
21. Hansen, C.A., Schroering, A.G., and Robishaw, J.D. (1995). Subunit expression of signal transducing G-proteins in cardiac tissue: implications for phospholipase C-beta regulation. J Mol Cell Cardiol 27, 471-479.
22. Horlick, R.A., and Benfield, P.A. (1989). The upstream muscle-specific enhancer of the rat muscle creatine kinase gene is composed of multiple elements. Mol Cell Biol 9(6), 2396-2413.
23. Kelly, G.M., Vanderbeld, B., Krawetz, R., and Mangos, S. (2001). Differential distribution of the G-protein gamma3 subunit in the zebrafish nervous system. Int J Dev Neurosci 19(4), 455-467.
24. Klamut, H.J., Bosnoyan-Collins, L., Worton, R., and Ray, P.N. (1997). A muscle-specific enhancer within intron 1 of the human dystrophin gene is functionally dependent on single MEF-1/E-box and MEF-2/AT-rich sequence motifs. Nucleic Acids Res 25(8), 1618-1625.
25. Kleuss, C., Scherubl, H., Hescheler, J., Schultz, G., and Wittig, H. (1993). Selectivity in signal transduction determined by gamma subunits of heterotrimeric G-proteins. Science 259, 832-834.
26. Kokubo, T., Takada, R., Yamashita, S., Gong, D.W., Roeder, R.G., Horikoshi, M., and Nakatani, Y. (1993). Identification of TFIID components required for transcriptional activation by upstream stimulatory factor. J Biol Chem 268(23), 17554-17558.
27. Kraus, R., Murray, E., Wiley, S., Zink, N., Loritz, K., Gelebiuk, G., and Mertz, J. (1996). Experimentally determined weight matrix definitions of the initiator (INR) and TBP binding site elements of promoter. Nucleic Acids Res 24, 1531-1539.
28. Kurokawa, M., Tanaka, T., Tanaka, K., Ogawa, S., Mitani, K., Yazaki, Y., and Hirai, H. (1994). Overexpression of the AML1 proto-oncoprotein in NIH3T3 cells leads to neoplastic transformation depending on the DNA-binding and transactivational potencies. Oncogene 12, 883-892.
29. Larkin, S.B., Farrance, I., and Ordahl, C.P. (1996). Flanking sequences modulate the cell specificity of M-CAT elements. Mol Cell Biol 16, 3742-3755.
30. Lassar, A., Buskin, D., Lockshon, R., Davis, R., Apone, S., Hauschka, S., and Weintraub, H. (1989). MyoD is a sequence specific DNA binding protein requiring a region of myc homology to bind to the muscle creatinine kinase enhancer. Cell 58, 823-831.
31. + channels in rat portal vein myocytes. J Biol Chem 272(37), 23180-23185.
32. Makaula, S., Adam, T., and Essop, M. (2006). Upstream stimulatory factor1 transactivates the human gene promoter of the cardiac isoform of acetyl-CoA carboxylase. Arch Biochem Biophys 446, 91-100.
33. McTiernan, C.F., Frye, C., Lemster, B., Kinder, E., Ogletree-Hughes, M., Moravec, C., and Feldman, A.M. (1999). The human phospholamban gene: structure and expression. J Mol Cell Cardiol 31, 679-692.
34. McWhinney, C.D. (1996). A downstream AP-1 element regulates in vitro lung transcription from the human pulmonary surfactant protein B promoter. DNA Cell Biol, 15, 519-529.
35. McWhinney, C.D., Hunt, R.A., Conrad, K.M., Dostal, D.E., and Baker, K.M. (1997). The type I angiotensin II receptor couples to Stat1 and Stat3 activation through Jak2 kinase in neonatal rat cardiac myocytes. J Mol Cell Cardiol 29, 2513-2524.
36. McWhinney, C., Wenham, D., Kanwal, S., Kalman, V., Hansen, C., and Robishaw, J.D. (2000a). Constitutively active mutants of the alpha1a- and the alpha1b-adrenergic receptor subtypes reveal coupling to different signaling pathways and physiological responses in rat cardiac myocytes. J Biol Chem 275(3), 2087-2097.
37. McWhinney, C.D., Hansen, C., and Robishaw, J.D. (2000b). Alpha-1 adreneric signaling in a cardiac murine atrial myocyte (HL-1) cell line. Mol Cell Biochem 214, 111-119.
38. Molkentin, J.D., and Markham, B.E. (1994). An M-CAT binding factor and a RSRF-related A-rich binding factor positively regulate expression of the alpha-cardiac myosin heavy chain gene in vivo. Mol Cell Biol 14(8), 5056-5065.
39. Muhlhauser, U., Zolk, O., Rau, T., Munzel, F., Wieland, T., and Eschenhagen, T. (2006). Atorvastatin desensitizes beta-adrenergic signaling in cardiac myocytes via reduced isoprenylation of G-protein-g-subunits. FASEB J 20(6), 785-787.
40. Navankasattusas, S., Sawadogo, M., van Bilsen, M., Dang, C.V., and Chien, K.R. (1994). The basic helix-loop-helix protein upstream stimulating factor regulates the cardiac ventricular myosin light-chain-2 gene via independent cis regulatory elements. Mol Cell Biol 14(11), 7331-7339.
41. Neer, E.J. (1995). Heterotrimeric G-proteins: organizers of transmembrane signals. Cell 80, 249-257.
42. Richardson, M., and Robishaw, J.D. (1999). The alpha2A-adrenergic receptor discriminates between Gi heterotrimers of different beta-gamma subunit composition in Sf9 cell membranes. J Biol Chem 274(19), 13525-13533.
43. Roy, A.L., Meisteernst, M., Pognonec, P., and Roeder, R.G. (1991). Cooperative interaction of an initiator-binding transcription initiation factor and the helix-loop-helix activator USF. Nature 354(6350), 245-248.
44. Schwindinger, W.F., Giger, K.E., Betz, K.S., Stauffer, A., Sunderlin, E., Sim-Selly, L., Selley, D., Bronson, S.K., and Robishaw, J.D. (2004). Mice with deficiency of G-Protein gamma3 are lean and have seizures. Mol Cell Biol 24(17), 7758-7768.
45. Stewart, A., Suzow, J., Kubota, T., Ueyama, T., and Chen, H.H. (1998). Transcription factor RTEF-1 mediates alpha-1-adrenergic reactivation of the fetal gene program in cardiac myocytes. Circ Res 83(1), 3-9.
46. Thuerauf, D.J., and Glembotski, C.C. (1997). Differential effects of protein kinase C, Ras, and Raf-1 on the induction of the cardiac B-type natriuretic peptide gene through a critical promoter-proximal M-CAT element. J Biol Chem 272(11), 7464-7472.
47. Wickman, K., Iniguez-Liuhi, J., Davenport, P., Taussig, R., Krapivinsky, G., Linder, M., Gilman, A.G., and Clapham, D.E. (1994). Recombinant G-protein beta-gamma subunits activate the muscarinic-gate atrial potassium channel. Nature 368, 255-257.
48. Xiao, Q., Kenessey, A., and Ojamaa, K. (2002). Role of USF1 phosphorylation on cardiac alpha-myosin heavy chain promoter activity. Am J Physiol 283(1), H213-H219.
49. Zhou, J.Y., Toth, P.T., and Miller, R.J. (2003). Direct interactions between the heterotrimeric G-protein subunit Gβ5 and the G-protein γ subunit-like domain-containing regulator of G-protein signaling 11: gain of function of cyan fluorescent protein-tagged G γ3. J Pharmacol Exp Ther 305(2), 460-466.