Structure and mapping of the G protein γ3 subunit gene and a divergently transcribed novel gene, Gng3lg

Genomics

Volumn 53, Issue 2, 1998, Pages 220-230

  Downes, Gerald B ^a   Copeland, Neal G ^b   Jenkins, Nancy A ^b   Gautam, N ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; GUANINE NUCLEOTIDE BINDING PROTEIN; MESSENGER RNA;

ANIMAL TISSUE; ARTICLE; BRAIN; DNA FLANKING REGION; GENE EXPRESSION REGULATION; GENE MAPPING; GENE STRUCTURE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TESTIS; TISSUE DISTRIBUTION; TRANSCRIPTION INITIATION;

ANIMALIA; MAMMALIA; RODENTIA;

EID: 17144462206     PISSN: 08887543     EISSN: None     Source Type: Journal    
DOI: 10.1006/geno.1998.5508     Document Type: Article

References (34)

1. Asano T., Morishita R., Ohashi K., Nagahama M., Miyake T., Kato K. Localization of various forms of the γ subunit of G protein in neural and nonneural tissues. J. Neurochem. 64:1995;1267-1273.
2. Blot S., Poivier C., Dreyfus P. A. The mouse mutation muscle deficient (mdf) is characterized by a progressive motoneuron disease. J. Neuropathol. Exp. Neurol. 54:1995;812-825.
3. Brenner V., Nyakatura G., Rosenthal A., Platzer M. Genomic organization of two novel genes on human Xq28: Compact head to head arrangement of IDH γ and TRAP δ is conserved in rat and mouse. Genomics. 44:1997;8-14.
4. Burbelo P. D., Martin G. R., Yamada Y. Alpha 1(IV) and alpha 2(IV) collagen genes are regulated by a bidirectional promoter and a shared enhancer. Proc. Natl. Acad. Sci. USA. 85:1988;9679-9682.
5. Cali J. J., Balcueva E. A., Rybalkin I., Robishaw J. D. Selective tissue distribution of G protein γ subunits, including a new form of the γ subunits identified by cDNA cloning. J. Biol. Chem. 267:1992;24023-24027.
6. Chang J. T., Milligan S., Li Y., Chew C. E., Wiggs J., Copeland N. G., Jenkins N. A., Campochiaro P. A., Hyde D. R., Zack D. J. Mammalian homolog ofDrosophila retinal degeration B. J. Neurosci. 17:1997;5881-5890.
7. Copeland N. G., Jenkins N. A. Development and applications of a molecular genetic linkage map of the mouse genome. Trends Genet. 7:1991;113-118.
8. Fisher K. J., Aronson N. N. Jr. Characterization of the cDNA and genomic sequence of a G protein γ subunit (γ 5). Mol. Cell. Biol. 12:1992;1585-1591.
9. Fujii H., Shimada T. Isolation and characterization of cDNA clones derived from the divergently transcribed gene in the region upstream from the human dihydrofolate reductase gene. J. Biol. Chem. 264:1989;10057-10064.
10. Gallagher C., Gautam N. Design of oligonucleotide probes for molecular cloning of β and γ subunits. Methods Enzymol. 237:1994;471-482.
11. Garson K., Duhig T., Armes N., Colombo P., Fried M. Surf5: A gene in the tightly clustered mouse surfeit locus is highly conserved and transcribed divergently from the rpL7A (Surf3) gene. Genomics. 30:1995;163-170.
12. Gautam N., Downes G. B., Yan K., Kisselev O. The G protein βγ complex. Cell. Signalling. 10:1998;447-455.
13. Gautam N., Northup J., Tamir H., Simon M. I. G protein diversity is increased by associations with a variety of γ subunits. Proc. Natl. Acad. Sci. USA. 87:1990;7973-7977.
14. Gudermann T., Kalkbrenner F., Schultz G. Functional and structural complexity of signal transduction via G-protein-coupled receptors. Annu. Rev. Pharmacol. Toxicol. 36:1996;429-459.
15. Iwaki A., Nagano T., Nakagawa M., Iwaki T., Fukumaki Y. Identification and characterization of the gene encoding a new member of the α-crystallin/small hsp family, closely linked to the αB- crystallin gene in a head-to-head manner. Genomics. 45:1997;386-394.
16. Jenkins N. A., Copeland N. G., Taylor B. A., Lee B. K. Organization, distribution, and stability of endogenous ecotropic murine leukemia virus DNA sequences in chromosomes ofMus musculus. J. Virol. 43:1982;26-36.
17. Kalyanaraman S., Copeland N. G., Gilbert D. G., Jenkins N. A., Gautam N. Structure and chromosomal localization of mouse G protein subunit γ4 gene. Genomics. 49:1998;147-151.
18. Kalyanaraman S., Kalyanaraman V., Gautam N. A brain-specific G protein gamma subunit. Biochem. Biophys. Res. Commun. 216:1995;126-132.
19. Kaytes P., Wood L., Theriault N., Kurkinen M., Vogeli G. Head-to-head arrangement of murine type IV collagen genes. J. Biol. Chem. 263:1988;19274-19277.
20. Kleuss C., Scherubl H., Hescheler J., Schultz G., Wittig B. Selectivity in signal transduction determined by γ subunits of heterotrimeric G proteins. Science. 259:1993;832-834.
21. Linton J. P., Yen J. Y., Selby E., Chen Z., Chinsky J. M., Liu K., Kellems R. E., Crouse G. F. Dual bidirectional promoters at the mouse dhfr locus: Cloning and characterization of two mRNA classes of the divergently transcribed Rep-1 gene. Mol. Cell. Biol. 9:1989;3058-3072.
22. Morishita R., Saga S., Kawamura N., Hashizume Y., Inagaki T., Kato K., Asano T. Differential localization of the γ 3 and γ 12 subunits of G proteins in the mammalian brain. J. Neurochem. 68:1997;820-827.
23. Ong O. C., Hu K., Rong H., Lee R. H., Fung B. K. Gene structure and chromosome localization of the G gamma c subunit of human cone G-protein (GNGT2). Genomics. 44:1997;101-109.
24. Ong O. C., Yamane H. K., Phan K. B., Fong H. K., Bok D., Lee R. H., Fung B. K. Molecular cloning and characterization of the G protein γ subunit of cone photoreceptors. J. Biol. Chem. 270:1995;8495-8500.
25. Poirier C., Guenet J. L. Mouse chromosome 19. Mamm. Genome. 8:1998;353-360.
26. Poschl E., Pollner R., Kuhn K. The genes for the α 1(IV) and α 2(IV) chains of human basement membrane collagen type IV are arranged head-to-head and separated by a bidirectional promoter of unique structure. EMBO J. 7:1988;2687-2695.
27. Ray K., Kunsch C., Bonner L. M., Robishaw J. D. Isolation of cDNA clones encoding eight different human G protein γ subunits, including three novel forms designated the γ 4, γ 10, and γ 11 subunits. J. Biol. Chem. 270:1995;21765-21771.
28. Simon M. I., Strathmann M. P., Gautam N. Diversity of G proteins in signal transduction. Science. 252:1991;802-808.
29. Smale S. T. Transcription: Mechanisms and Regulation. 1994;Raven Press, New York.
30. Soininen R., Huotari M., Hostikka S. L., Prockop D. J., Tryggvason K. The structural genes for α 1 and α 2 chains of human type IV collagen are divergently encoded on opposite DNA strands and have an overlapping promoter region. J. Biol. Chem. 263:1988;17217-17220.
31. Tao L., Pandey S., Simon M. I., Fong H. K. Structure of the bovine transducin γ subunit gene and analysis of promoter function in transgenic mice. Exp. Eye Res. 56:1993;497-507.
32. Williams T. J., Fried M. The MES-1 murine enhancer element is closely associated with the heterogeneous 5′ ends of two divergent transcription units. Mol. Cell. Biol. 6:1986;4558-4569.
33. Womack J. E., MacPike A., Meier H. Muscle deficient, a new mutation in the mouse. J. Hered. 71:1980;68.
34. Yan K., Kalyanaraman V., Gautam N. Differential ability to form the G protein βγ complex among members of the β and γ subunit families. J. Biol. Chem. 271:1996;7141-7146.