Helix tilt of the M2 transmembrane peptide from influenza A virus: An intrinsic property

Journal of Molecular Biology

Volumn 295, Issue 1, 2000, Pages 117-125

  Kovacs, F A ^a   Denny, Jeffrey K ^a,b   Song, Z ^a   Quine, J R ^a   Cross, T A ^a,b  

^a FLORIDA STATE UNIVERSITY   (United States)

^b FLORIDA STATE UNIVERSITY   (United States)

Author keywords

15N chemical shift; Ion channel; Membrane protein; Orientational constraints; Solid state NMR

Indexed keywords

DIMYRISTOYLPHOSPHATIDYLCHOLINE; DIOLEOYLPHOSPHATIDYLCHOLINE; ION CHANNEL; MEMBRANE PROTEIN; NITROGEN 15; VIRUS PROTEIN;

ARTICLE; CIRCULAR DICHROISM; CONTROLLED STUDY; HYDROPHOBICITY; INFLUENZA VIRUS A; LIPID BILAYER; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL;

INFLUENZA A VIRUS; INFLUENZA VIRUS; INFLUENZAVIRUS A; RNA VIRUSES;

EID: 0034614541     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1999.3322     Document Type: Article

References (40)

1. Bauer C. M., Pinto L. H., Cross T. A., Lamb R. A. The influenza virus M2 ion channel protein probing the structure of the transmembrane domain in intact cells by using engineered disulfide cross-linking. Virology. 254:1999;196-209.
2. Cross T. A. Structural biology of peptides and proteins in synthetic membrane environments by solid-state NMR Spectroscopy. Annu. Rep. NMR Spectrosc. 29:1994;124-167.
3. Cross T. A., Opella S. J. Solid-state NMR structural studies of peptides and proteins in membranes. Curr. Opin. Struct. Biol. 4:1994;574-581.
4. 2H NMR and ESR study using designed transmembrane α-helical peptides and gramicidin A. Biochemistry. 37:1998;9333-9345.
5. Duff K. C., Ashley R. H. The transmembrane domain of influenza A M2 protein forms amantadine-sensitive proton channels in planar lipid bilayers. Virology. 190:1992;485-489.
6. Duff K. C., Kelly S. M., Price N. C., Bradshaw J. P. The secondary structure of influenza A M2 transmembrane domain. A circular dichroism study. FEBS Letters. 311:1992;256-258.
7. 15N-gramicidins A, B, and C and high performance liquid chromatographic purification. Int. J. Pept. Protein Res. 33:1989;298-304.
8. 1] gramicidin A. Proc. Natl Acad. Sci. USA. 85:1988;1384-1388.
9. Fu R., Cross T. A. Solid-state NMR magnetic resonance investigation of protein and polypeptide structure. Annu. Rev. Biophys. Biomol. Struct. 28:1999;235-268.
10. Gröbner G., Choi G., Burnett I. J., Glaubitz C., Verdegem P. J. E., Watts A. Photoreceptor Rhodopsin: structural and conformational study of its chromophore 11-cis retinal in oriented membranes by deuterium solid-state NMR. FEBS Letters. 422:1998;201-204.
11. Hay A. J. The action of adamantamines against influenza A virus: inhibition of the M2 ion channel protein. Semin. Virol. 3:1992;21-30.
12. Holsinger L. J., Lamb R. A. Influenza virus M2 integral membrane protein is a homotetramer stabilized by formation of disulfide bonds. Virology. 183:1991;32-43.
13. Ketchem R. R., Hu W., Cross T. A. High-resolution conformation of gramicidin A in a lipid bilayer by solid state NMR. Science. 261:1993;1457-1460.
14. Ketchem R. R., Lee K. C., Huo S., Cross T. A. Macromolecular structural elucidation with solid-state NMR-derived orientational constraints. J. Biomol. NMR. 8:1996;1-14.
15. Killian J. A. Hydrophobic mismatch between proteins and lipids in membranes. Biochim. Biophys. Acta. 1376:1998;401-416.
16. Killian J. A., Salemink I., de Planque M. R. R., Lindblom G., Koeppe R. E. II, Greathouse D. V. Induction of nonbilayer structures in diacylphosphatidylcholine model membranes by transmembrane α-helical peptides: importance of hydrophobic mismatch and proposed role of tryptophans. Biochemistry. 35:1996;1037-1045.
17. Kim Y., Valentine K., Opella S. J., Schendel S. L., Cramer W. A. Solid-state NMR studies of the membrane-bound closed state of the colicin E1 channel domain in lipid bilayers. Protein Sci. 7:1998;342-348.
18. Kovacs F. A., Cross T. A. Transmembrane four-helix bundle of influenza A M2 protein channel: structural implications from helix tilt and organization. Biophys. J. 73:1997;2511-2517.
19. + channel. J. Mol. Biol. 286:1999;951-962.
20. Lamb R. A., Krug R. M. Orthomyxoviridae: the viruses and their replication. Fields B. N., Knipe D. M., Howley P. M. et al. Fields Virology. 1996;Lippincot-Raven Publishers, Philadelphia.
21. Lamb R. A., Zebedee S. L., Richardson C. D. Influenza virus M2 protein is an integral membrane protein expressed on the infected-cell surface. Cell. 40:1985;627-633.
22. Lazo N. D., Hu W., Lee K.-C., Cross T. A. Rapidly-frozen polypeptide samples for characterization of high definition dynamics by solid-state NMR spectroscopy. Biochem. Biophys. Res. Commun. 197:1993;904-909.
23. Lewis B. A., Engelman D. M. Lipid bilayer thickness varies linearly with acyl chain length in fluid phosphatidylcholine vesicles. J. Mol. Biol. 166:1983;211-217.
24. Mai W., Hu W., Wang C., Cross T. A. Orientational constraints as three-dimensional structural constraints from chemical shift anisotropy: the polypeptide backbone of gramicidin A in a lipid bilayer. Protein Sci. 2:1993;532-542.
25. Morein S., Strandberg E., Killian A., Persson S., Arvidson G., Koeppe R. E. II, Lindblom G. Influence of membrane-spanning α-helical peptides on the phase behavior of the dioleoylphosphatidylcholine/water system. Biophys. J. 73:1997;3078-3088.
26. Opella S. J., Marassi F. M., Gesell J. J., Valente A. P., Kim Y., Oblatt-Montal M., Montal M. Structures of the M2 channel-lining segments from nicotinic acetylcholine and NMDA receptors by NMR spectroscopy. Nature. 6:1999;374-379.
27. 2 protein of influenza A H1N1 viruses. Virology. 186:1992;352-355.
28. Pinto L. H., Holsinger L. J., Lamb R. A. Influenza virus M2 protein has ion channel activity. Cell. 69:1992;517-528.
29. 2 ion channel is a tetramer. Proc. Natl Acad. Sci. USA. 94:1997;5000-5005.
30. Salom D., Lear J. D., DeGrado W. F. Aggregation of influenza A M2 transmembrane segment in micelles. Biophys. J. 76:1999;A123.
31. Scherer J. R. On the position of the hydrophobic/hydrophilic boundary. Biophys. J. 55:1989;957-964.
32. 2 ion channel of influenza virus. Biophys. J. 70:1996;1335-1346.
33. Shon K.-J., Kim Y., Colnago L. A., Opella S. J. NMR studies of the structure and dynamics of membrane-bound bacteriophage Pf1 coat protein. Science. 252:1991;1303-1308.
34. Sugrue R. J., Hay A. J. Structural characteristics of the M2 protein of influenza A viruses: evidence that it forms a tetrameric channel. Virology. 180:1991;617-624.
35. 15N chemical-shift tensor orientation in a polypeptide. J. Magn. Reson. 85:1989;439-447.
36. Tu W., Pinto L. H., Luo G., Shaughnessy M. A., Mullaney D., Kurtz S., Krystal M., Lamb R. A. Characterization of inhibition of M2 ion channel activity by BL-1743, an inhibitor of influenza A virus. J. Virol. 70:1996;4246-4252.
37. Wang C., Takeuchi K., Pinto L. H., Lamb R. A. Ion channel activity of influenza A virus M2 protein: characterization of the amantadine block. J. Virol. 67:1993;5585-5594.
38. Weiner M. C., White S. H. Structure of a fluid dioleoylphosphatidylcholine bilayer determined by joint refinement of x-ray and neutron diffraction data. III. Complete structure. Biophys. J. 61:1992;434-447.
39. Wu C. H., Ramamoorthy A., Opella S. J. High resolution neteronuclear dipolar solid-state NMR spectroscopy. J. Magn. Reson. ser. A. 109:1994;270-272.
40. Yang J. T., Wu C. S., Martinez H. M. Calculation of protein conformation from circular dichroism. Methods Enzymol. 130:1986;208-269.