Monitoring in vivo metabolism and elimination of the endogenous DNA adduct, M1dG {3-(2-Deoxy-β-D-erythropentofuranosyl)pyrimido[1,2- α]purin-10(3H)-one}, by accelerator mass spectrometry

Chemical Research in Toxicology

Volumn 21, Issue 6, 2008, Pages 1290-1294

  Knutson, Charles G ^a   Skipper, Paul L ^b   Liberman, Rosa G ^b   Tannenbaum, Steven R ^b   Marnett, Lawrence J ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Massachusetts Institute of Technology Cambridge   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 (2 DEOXY BETA DEXTRO ERYTHRO PENTOFURANOSYL)PYRIMIDO[L,2 ALPHA]PURIN L0(3H) ONE; 6 OXO 3 (2 DEOXY BETA DEXTRO ERYTHRO PENTOFURANOSYL)PYRIMIDO[L,2 ALPHA]PURIN 10(3H) ONE; PURINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOLOGICAL MONITORING; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DNA ADDUCT; DNA METABOLISM; FECES LEVEL; MALE; MASS SPECTROMETRY; METABOLITE; NONHUMAN; OXIDATIVE STRESS; PEROXIDATION; RAT; URINALYSIS;

ANIMALS; DNA ADDUCTS; FECES; MALE; MASS SPECTROMETRY; PURINE NUCLEOSIDES; RATS; RATS, SPRAGUE-DAWLEY; URINE;

EID: 47049085037     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx800049v     Document Type: Article

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