Characterization of a subset of bone marrow-derived natural killer cells that regulates T cell activation in rats

Journal of Leukocyte Biology

Volumn 83, Issue 5, 2008, Pages 1128-1135

  Kheradmand, Taba ^a   Trivedi, Prachi P ^a,b   Wolf, Norbert A ^a   Roberts, Paul C ^a,c   Swanborg, Robert H ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b HARVARD UNIVERSITY   (United States)

^c VIRGINIA MARYLAND REGIONAL COLLEGE OF VETERINARY MEDICINE   (United States)

Author keywords

Cytokines; Suppression; Tolerance

Indexed keywords

CD3 ANTIGEN; CONCANAVALIN A; IONOMYCIN; N(G) METHYLARGININE; NITRIC OXIDE SYNTHASE INHIBITOR;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE; CELL CLONE; CERVICAL LYMPH NODE; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOKINE PRODUCTION; DARK AGOUTI RAT; DOWN REGULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FISCHER 344 RAT; FLOW CYTOMETRY; HOMEOSTASIS; INHIBITION KINETICS; LYMPHOCYTE; LYMPHOCYTE PROLIFERATION; LYMPHOCYTE SUBPOPULATION; MESENTERY LYMPH NODE; NATURAL KILLER CELL; NONHUMAN; PEYER PATCH; PRIORITY JOURNAL; RAT; SPLEEN LYMPHOCYTE; SUPERNATANT; T LYMPHOCYTE ACTIVATION;

ANIMALS; BONE MARROW CELLS; CELL DIVISION; HOMEOSTASIS; IONOMYCIN; KILLER CELLS, NATURAL; LYMPHOCYTE ACTIVATION; OMEGA-N-METHYLARGININE; RATS; RATS, INBRED F344; RATS, SPRAGUE-DAWLEY; T-LYMPHOCYTES; TISSUE EXPANSION;

RATTUS;

EID: 46949108180     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0907626     Document Type: Article

References (29)

1. Moretta, L., Biassoni, R., Bottino, C., Mingari, M. C., Moretta, A. (2002) Natural killer cells: a mystery no more. Scand. J. Immunol. 55, 229-232.
2. Yokoyama, W. Kim, M. S., French, A. R. (2004) The dynamic life of natural killer cells. Annu. Rev. Immunol. 22, 405-429.
3. bright subset. Blood 97, 3146-3151.
4. Robertson, M. J. (2002) Role of chemokines in the biology of natural killer cells. J. Leukoc. Biol. 71, 173-183.
5. Hayakawa, Y., Smyth, M. J. (2006) CD27 dissects mature NK cells into two subsets with distinct responsiveness and migratory capacity. J. Immunol. 176, 1517-1524.
6. Koopman, L. A., Kopcow, H. D., Rybalov, B., Boyson, J. E., Orange, J. S., Schatz, F., Masch, F. R., Lockwood, C. J., Schachter, A. D., Park, P. J., et al. (2003) Human decidual natural killer cells are a unique NK cell subset with immunomodulatory potential. J. Exp. Med. 198, 1201-1212.
7. Kim, S., Iizuka, K., Kang, H.-S., Dokun, A., French, A. R., Greco, S., Yokoyama, W. M. (2002) In vivo developmental stages in murine natural killer cell maturation. Nat. Immunol. 3, 523-528.
8. Smeltz, R. B., Wolf, N. A., Swanborg, R. H. (1999) Inhibition of autoimmune T cell responses in the DA rat by bone marrow-derived natural killer cells in vitro: implications for autoimmunity. J. Immunol. 163, 1390-1397.
9. Trivedi, P. P., Roberts, P. C., Wolf, N. A., Swanborg, R. H. (2005) NK cells inhibit T cell proliferation via p21-mediated cell cycle arrest. J. Immunol. 174, 4590-4597.
10. Swanborg, R. H., Stepaniak, J. A. (1996) Experimental autoimmune encephalomyelitis in the rat. In Current Protocols in Immunology, vol. 3. (J. E. Coligan, A. M. Kruisbeek, D. H. Margulies, E. M. Shevach, and W. Strober, eds.) Wiley, New York, pp. 15.2.1-15.2.14.
11. - cells inhibit autoreactive T cell responses. J. Neuroimmunol. 119, 81-87.
12. Assarsson, E., Kambayashi, T., Schatzle, J. D., Cramer, S. O., von Bonin, A., Jenson, P. E., Ljunggren, H.-G., Chambers, B. J. (2004) NK cells stimulate proliferation of T and NK cells through 2B4/CD48 interactions. J. Immunol. 173, 174-180.
13. Upham, J. W., Strickland, D. H., Bilyk, N., Robinson, B. W. S., Holt, P. G. (1995) Alveolar macrophages from humans and rodents selectively inhibit T-cell proliferation but permit T-cell activation and cytokine secretion. Immunology 84, 142-147.
14. Kopcow, H. D., Allan, D. S. J., Chen, X., Rybalov, B., Andzeim, M. M., Ge, B., Strominger, J. L. (2005) Human decidual NK cells form immature activating synapses and are not cytotoxic. Proc. Natl. Acad. Sci. USA 102, 15563-15568.
15. Mangan, K. F., Hartnett, M. E., Matis, S. A., Winkelstein, A., Abo, T. (1984) Natural killer cells suppress human erythroid stem cell proliferation in vitro. Blood 63, 260-269.
16. Holmberg, L. A., Miller, B. A., Ault, F. A. (1984) The effect of natural killer cells on the development of syngeneic hematopoietic progenitors. J. Immunol. 133, 2933-2939.
17. Degliantoni, G., Perussia, B., Mangoni, L., Trinchieri, G. (1985) Inhibition of bone marrow colony formatiion by human natural killer cells and by natural killer cell-derived colony-inhibiting activity. J. Exp. Med. 161, 1152-1168.
18. Matsumoto, Y., Kohyama, K., Aikawa, Y., Shin, T., Kawazoe, Y., Suzuki, Y., Tanuma, N. (1998) Role of natural killer cells and TCRgd T cells in acute autoimmune encephalomyelitis. Eur. J. Immunol. 28, 1681-1688.
19. Zhang, B.-n., Yamamura, T., Kondo, T., Fujiwara, M., Tabira, T. (1997) Regulation of experimental autoimmune encephalomyelitis by natural killer (NK) cells. J. Exp. Med. 186, 1677-1687.
20. Todd, D. J., Forsberg, E. M., Greiner, D. L., Mordes, J. P., Rossini, A. A., Bortell, R. (2004) Deficiencies in gut NK cell number and function precede diabetes onset in BB rats. J. Immunol. 172, 5356-5362.
21. bright natural killer cells mediate immunomodulatory effects of IL-2Ra-targeted therapy (daclizumab) in multiple sclerosis. Proc. Natl. Acad. Sci. USA 103, 5941-5946.
22. bright regulatory NK cells in patients with active uveitis. J. Immunol. 174, 5187-5191.
23. Xu, W., Fazekas, G., Hara, H., Tabira, T. (2005) Mechanism of natural killer (NK) cell regulatory role in experimental autoimmune encephalomyelitis. J. Neuroimmunol. 163, 24-30.
24. Berg, L., Rönnelid, J., Klareskog, L., Bucht, A. (2000) Down-regulation of the T cell receptor CD3ζ chain in rheumatoid arthritis (RA) and its influence on T cell responsiveness. Clin. Exp. Immunol. 120, 174-182.
25. Chen, C., Lee, W.-h., Liu, C. P. (2006) Regulatory T cells can mediate their function through the stimulation of APCs to produce immunosuppressive nitric oxide. J. Immunol. 176, 3449-3460.
26. Cifone, M. G., Ulisse, S., Santoni, A. (2001) Natural killer cells and nitric oxide. Int. Immunopharmacol. 1, 1513-1524.
27. O'Brien, N. C., Charlton, B., Cowden, W. B., Willenborg, D. O. (2001) Inhibition of nitric oxide synthase initiates relapsing remitting experimental autoimmune encephalomyelitis in rats, yet nitric oxide appears to be essential for clinical expression of disease. J. Immunol. 167, 5904-5912.
28. Becker, T. C., Coley, S. M., Wherry, J., Ahmed, R. (2005) Bone marrow is a preferred site for homeostatic proliferation of memory CD8 T cells. J. Immunol. 174, 1269-1273.
29. Mazo, I. B., Honczarenko, M., Leung, H., Cavanaugh, L. L., Bonasio, R., Weninger, W., Engelke, K., Xia, L., McEver, P., Koni, P. A., et al. (2005) Bone marrow is a major reservoir and site of recruitment for central memory CD8+ T cells. Immunity 22, 259-270.