Pharmacokinetics of doxycycline and tissue concentrations of an experimental long-acting parenteral formulation of doxycycline in Wistar rats

Arzneimittel-Forschung/Drug Research

Volumn 58, Issue 6, 2008, Pages 310-315

  Vargas Estrada, Dinorah ^a   Gutiérrez, Lilia ^a   Juarez Rodríguez, Ivan ^a   Sumano, Héctor ^a  

^a UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

Author keywords

Antibacterials; CAS 24390 14 5; Doxycycline; Pharmacokinetics; Rat; Sustained release

Indexed keywords

BETA CYCLODEXTRIN; DOXYCYCLINE HYCLATE; POLOXAMER;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBACTERIAL ACTIVITY; ANTIBIOTIC SENSITIVITY; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG DOSAGE FORM COMPARISON; DRUG ELIMINATION; DRUG FORMULATION; DRUG HALF LIFE; DRUG SAFETY; HISTOPATHOLOGY; INTESTINE; KIDNEY PARENCHYMA; LUNG PARENCHYMA; MALE; MAXIMUM PLASMA CONCENTRATION; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PLASMA CONCENTRATION-TIME CURVE; RAT; SINGLE DRUG DOSE; SUSTAINED DRUG RELEASE; TISSUE HOMOGENATE; WISTAR RAT;

EID: 46949092895     PISSN: 00044172     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0031-1296512     Document Type: Article

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