Pharmacokinetics of doxycycline after administration as a single intravenous bolus and intramuscular doses to non-lactating Egyptian goats

Pharmacological Research

Volumn 49, Issue 5, 2004, Pages 487-491

  Abd El Aty, A M ^a   Goudah, A ^a   Zhou, H H ^b  

^a Cairo University   (Egypt)

^b The First People s Hospital of Changde City)   (China)

Author keywords

Bioavailability; Doxycycline hydrochloride; Goats; Pharmacokinetics

Indexed keywords

DOXYCYCLINE; PLASMA PROTEIN;

ANIMAL EXPERIMENT; ARTICLE; BACILLUS SUBTILIS; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG HALF LIFE; DRUG PROTEIN BINDING; DRUG URINE LEVEL; FEMALE; GOAT; MICROBIOLOGY; NONHUMAN; PLASMA PROTEIN BINDING; PRIORITY JOURNAL;

ANIMALS; AREA UNDER CURVE; BACILLUS SUBTILIS; BIOLOGICAL AVAILABILITY; DOXYCYCLINE; DRUG EVALUATION, PRECLINICAL; EGYPT; FEMALE; GOATS; HALF-LIFE; INJECTIONS, INTRAMUSCULAR; INJECTIONS, INTRAVENOUS; METABOLIC CLEARANCE RATE; METHODS; TIME FACTORS;

EID: 1442309145     PISSN: 10436618     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phrs.2003.10.012     Document Type: Article

References (24)

1. Suzuka I., Kaji H., Kaji A. Binding of specific sRNA to 30S ribosomal subunits: effects of 50S ribosomal subunits. Proc. Natl. Acad. Sci. 55:1966;1483-1486.
2. Cunha B.A., Sibley C.M., Ristuccia A.M. Doxycycline. Ther. Drug Monit. 4:1982;115-135.
3. Raghuram T.C., Krishnaswamy K. Pharmacokinetics and plasma steady state level of doxycycline in undernutrition. Br. J. Clin. Pharmacol. 14:1982;785-789.
4. Wilson R.C., Kemp D.T., Kitzman J.V., Goetsch D.D. Pharmacokinetics of doxycycline in dogs. Can. J. Vet. Res. 52:1988;12-14.
5. Riond J.L., Riviere J.E. Doxycycline binding to plasma albumin of several species. J. Vet. Pharmacol. Ther. 12:1989;253-260.
6. Riond J.L., Riviere J.E. Pharmacokinetics and metabolic inertness of doxycycline in young pigs. Am. J. Vet. Res. 51:1990;1271-1275.
7. Riond J.L., Vaden S.L., Riviere J.E. Comparative pharmacokinetics of doxycycline in cats and dogs. J. Vet. Pharmacol. Ther. 13:1990;415-424.
8. Kelly D.J., Chulay J.D., Mikesell P., Friedlander A.M. Serum concentrations of penicillin, doxycycline, and ciprofloxacin during prolonged therapy in rhesus monkey. J. Infect. Dis. 166:1992;1184-1187.
9. Prus S.E., Clubb S.L., Flammer K. Doxycycline plasma concentrations in macaws fed a medicated corn diet. Avian Dis. 36:1992;480-483.
10. Greth A., Gerlsch H., Gerbermann H., Vassart M., Richez P. Pharmacokinetics of doxycycline after parenteral administration in the Houbara Bustard (Chlamydotis Undulata). Avian Dis. 37:1993;31-36.
11. Meijer L.A., Ceyssens K.G.F., de Greve B.I., de Bruijn W. Pharmacokinetics and bioavailability of doxycycline hyclate after oral administration in calves. Vet. Quarter. 15:1993;1-5.
12. Jha V.K., Jayachandran C., Singh M.K., Singh S.D. Pharmacokinetic data on doxycycline and its distribution in different biological fluids in female goats. Vet. Res. Commun. 13:1989;11-16.
13. Bennett J.V., Brodie J.L., Benner E.J., Kirby W.M. Simplified, accurate method for antibiotic assay of clinical specimens. Appl. Microbiol. 14:1966;170-177.
14. Craig AW, Suh B. Protein binding and the antibacterial effects. Methods for determination of protein binding. In: Lorian V, editor. Antibiotics in laboratory medicine, Baltimore, Maryland: Williams and Wilkins; 1980. p. 265-97.
15. Gibaldi M, Perrier D. Pharmacokinetics, 2nd Ed, New York: Marcel Dekker, Inc.; 1982. p. 409-17.
16. Yamaoka K., Nakagawa T., Uno T. Statistical moment in pharmacokinetics. J. Pharmacokinet. Biopharmacodyn. 6:1978;547-558.
17. Ziv G., Sulman F.G. Analysis of pharmacokinetic properties of nine tetracycline analogues in dairy cow and ewes. Am. J. Vet. Res. 35:1974;1197-1201.
18. Baruah K.K. Buffalo as a source of meat protein. Sci. Reporter. 21:1984;175-177.
19. Notari RE. Principles of pharmacokinetics: dosage regimen. In: Notari RE, editor. Biopharmaceutics and clinical pharmacokinetics an introduction, 3rd ed. New York: Marcel Dekker Inc.; 1980. p. 45-212.
20. Ceccarelli G., Rossoni R., Romita F., Naddeo A. Pharmacokinetic study of doxycycline in children. Chemotheraphy. 16:1971;1-10.
21. Bryant J.E., Brown M.P., Gronwall R.R., Merritt K.A. Study of intragastric administration of doxycycline pharmacokinetics including body fluids, endometrial and minimum inhibitory concentrations. Equine Vet. J. 32:2000;233-238.
22. Ole-Mapenay I.M., Mitema E.S. Some pharmacokinetic parameters of doxycycline in east African goats after intramuscular administration of a long acting formula. Vet. Res. Commun. 19:1995;425-432.
23. Ole-Mapenay I.M., Mitema E.S., Mathio T.E. Aspects of pharmacokinetics of doxycycline given to healthy and pneumonic east African dwarf goats by intramuscular injection. Vet. Res. Commun. 21:1997;453-462.
24. Toutain P.L., Del Castillo J.R.E., Bousquet-Mélou A. The pharmacokinetic-pharmacodynamic approach to a rational dosage regimen for antibiotics. Res. Vet. Sci. 73:2002;105-114.