Amino acid residues in the nicotinamide binding site contribute tocatalysis by horse liver alcohol dehydrogenase

Biochemistry

Volumn 42, Issue 10, 2003, Pages 2907-2915

  Rubach, Jon K ^a   Plapp, Bryce V ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COVALENT BONDS;

ALCOHOLS; CATALYSIS; CHEMICAL BONDS; COENZYMES; CONFORMATIONS; OXIDATION; RATE CONSTANTS;

AMINO ACIDS;

ALCOHOL DEHYDROGENASE; AMINO ACID; BENZYL ALCOHOL; NICOTINAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE; PYRAZOLE DERIVATIVE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; THREONINE; VALINE;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; BINDING SITE; CATALYSIS; COENZYME; CONFORMATION; COVALENT BOND; ENZYME KINETICS; MOLECULAR DYNAMICS; NONHUMAN; OXIDATION; PRIORITY JOURNAL; STEADY STATE;

ALCOHOL DEHYDROGENASE; AMINO ACID SUBSTITUTION; AMINO ACIDS; ANIMALS; BINDING SITES; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; HORSES; HYDROGEN; KINETICS; LIVER; MUTAGENESIS, SITE-DIRECTED; NAD; NIACINAMIDE; PROTEIN CONFORMATION; STRUCTURE-ACTIVITY RELATIONSHIP; VALINE;

EQUUS CABALLUS;

EID: 0037452898     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0272656     Document Type: Article

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