Cardiac markers (BNP, NT-pro-BNP, Troponin I, Troponin T) in female amateur runners before and up until three days after a marathon

Clinical Laboratory

Volumn 54, Issue 3-4, 2008, Pages 81-87

  Frassl, Waltraud ^a,g   Kowoll, R ^a   Katz, N ^b   Speth, M ^b   Stangl, A ^c   Brechtel, L ^d   Joscht, B ^e   Boldt, L H ^a   Meier Buttermilch, R ^f   Schlemmer, M ^a   Roecker, L ^f   Gunga, H C ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b JUSTUS LIEBIG UNIVERSITY   (Germany)

^c Bayer Vital GmbH   (Germany)

^d HUMBOLDT UNIVERSITY   (Germany)

^e Bundeswehrkrankenhaus Berlin   (Germany)

^f Department of Cardiology ^*  (Germany)

^g Psychiatry Center Hard   (Switzerland)

Author keywords

Endurance exercise; Natriuretic peptides; Troponin I; Troponin T

Indexed keywords

AMINO TERMINAL PRO BRAIN NATRIURETIC PEPTIDE; BIOLOGICAL MARKER; BRAIN NATRIURETIC PEPTIDE; TROPONIN I; TROPONIN T;

ADULT; ARTICLE; ATHLETE; ENDURANCE SPORT; FEMALE; GERMANY; HEART STRESS; HUMAN; MARATHON RUNNER; OCCUPATIONAL HEALTH; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; REFERENCE VALUE; WOMEN'S HEALTH;

ADULT; BIOLOGICAL MARKERS; CARDIOVASCULAR PHYSIOLOGICAL PHENOMENA; FEMALE; HUMANS; MIDDLE AGED; NATRIURETIC PEPTIDE, BRAIN; PEPTIDE FRAGMENTS; PHYSICAL EXERTION; RUNNING; TIME FACTORS; TROPONIN I; TROPONIN T;

ELAGATIS;

EID: 46849101006     PISSN: 14336510     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Clark BA, Elahi D, Epstein FH. The influence of gender, age, and the menstrual cycle on plasma atrial natriuretic peptide. J Clin Endocrinol Metab 1990; 70:349-352
2. Clerico A, Emdin M. Diagnostic accuracy and prognostic relevance of the measurement of cardiac natriuretic peptides: a review. Clin Chem 2004; 50:33-50
3. Giannitsis E, Katus HA. Comparison of cardiac troponin T and troponin I assays - implications of analytical and biochemical differences on clinical performance. Clin Lab 2004; 50:521-528.
4. Hall C. Essential biochemistry and physiology of (NT-pro)BNP. Eur J Heart Fail 2004; 15:257-260
5. Hammerer-Lercher A, Puschendorf B, Mair J. B-type natriuretic peptides as powerful markers in cardiac diseases - analytical and clinical aspects. J Lab Med 2006; 30:165-184
6. Herrmann M, Scharhag J, Miclea M, Urhausen A, Herrmann W, Kindermann W. Post-race kinetics of cardiac troponin T and I and N-terminal pro-B type natriuretic peptide in marathon runners. Clin Chem 2003; 49:831-834
7. Huang WS, Lee MS, Perng HW, Yang SP, Kuo SW, Chang HD. Circulating B type natriuretic peptide values in healthy men before and after exercise. Metabolism 2002; 51:1423-1426
8. Konig D, Schumacher YO, Heinrich L, Schmid A, Berg A, Dickhuth HH. Myocardial stress after competitive exercise in professional road cyclists. Med Sci Sports Exerc 2003; 35:1679-1683
9. Kratz A, Lewandrowski KB, Siegel AJ, Chun KY, Flood JG, Van Cott EM, Lee-Lewandrowski E. Effect of marathon running on hematologic and biochemical laboratory parameters, including cardiac markers. Am J Clin Pathol 2002; 118:856-863
10. Leers MP, Schepers R, Baumgarten R. Effects of a long-distance run on cardiac markers in healthy athletes. Clin Chem Lab Med 2006; 44:999-1003
11. Mair J, Puschendorf B. Kardiale Diagnostik. In: Thomas L (ed) Labor und Diagnose. Frankfurt/Main: TH - Books Verlags-gesellschaft, 6. Auflage: 121-158
12. McDonagh TA, Holmer S, Raymond I, Luchner A, Hildebrant P, Dargie HJ. NT-pro-BNP and the diagnosis of heart failure: a pooled analysis of three European epidemiological studies. Eur J Heart Fail 2004; 6:269-273
13. Möckel M, Danne O, Schmidt A, Goldmann M, Müller C, Dietz R, Wu AH. Reference values for cardiac troponins I and T in a goal-oriented concept of health: cardiac marker values in a series of outpatients without acute coronary syndromes. Clin Chim Acta 2004; 342:83-86
14. Möckel M, Störk T, Heller G Jr, Röcker L, Danne O, Darrelmann KG, Eichstädt H, Frei U. Troponin T in patients with low grade or atypical angina. Identification of a high risk group for short- and long-term cardiovascular events. Eur Heart J. 1998; 19:1802-1807
15. Neilan TG, Januzzi JL, Lee-Lewandrowski E, Ton-Nu TT, Yoerger DM, Jassal DS, Lewandrowski KB, Siegel AJ, Marshall JE, Douglas PS, Lawlor D, Picard MH, Wood MJ. Myocardial injury and ventricular dysfunction related to training levels among nonelite participants in the Boston Marathon. Circulation 2006; 114:2325-2333
16. Neumayr G, Pfister R, Mitterbauer G, Eibl G, Hoertnagl H. Effect of competitive marathon cycling on plasma N-terminal pro-B type natriuretic peptide and cardiac troponin T in healthy recreational cyclists. Am J Cardiol 2005; 96:732-735
17. Ohba H, Takada H, Musha H, Nagashima J, Mori N, Awaya T, Omiya K, Murayama M. Effects of prolonged strenuous exercise on plasma levels of atrial natriuretic peptide and B type natriuretic peptide in healthy men. Am Heart J 2001; 141:751-758
18. Panteghini M, Clerico A. Understanding the clinical biochemistry of N-terminal pro-B-type natriuretic peptide: the prerequisite for its optimal clinical use. Clin Lab 2004; 50:325-331
19. Sabatine MS, Morrow DA, de Lemos JA, Omland T, Desai MY, Tanasijevic M, Hall C, McCabe CH, Braunwald E. Acute changes in circulating natriuretic peptide levels in relation to myocardial ischemia. J Am Coll Cardiol 2004; 44:1988-1995
20. Scharhag J, Herrmann M, Urhausen A, Haschke M, Herrmann W, Kindermann W. Independent elevations of N-terminal pro-B type natriuretic peptide and cardiac troponins in endurance athletes after prolonged strenuous exercise. Am Heart J 2005; 150:1128-1134
21. Shave R, Dawson E, Whyte G, George K, Gaze D, Collinson P. Altered cardiac function and minimal cardiac damage during prolonged exercise. Med Sci Sports Exerc 2004; 36:1098-1103
22. Siegel AJ, Lewandrowski EL, Chun KY, Sholar MB, Fischman AJ, Lewandrowski KB. Changes in cardiac markers including B-natriuretic peptide in runners after the Boston Marathon. Am J Cardiol 2001; 88:920-923
23. Strauss MB, Davies RK, Rosenbaum JD, Rossmeisl EC. Water diuresis produced during recumbency by the intravenous infusion of isotonic saline solution. J Clin Invest 1951; 30:862-868
24. Suttner SW, Boldt J. Natriuretic peptide system: physiology and clinical utility. Curr Opin Crit Care 2004; 10:336-341
25. Suzuki M, Sudoh M, Matsubara S, Kawakami K, Shiota M, Ikawa S. Changes in renal blood flow measured by radionuclide angiograpliy following exhausting exercise in humans. Eur J Appl Physiol Occup Physiol 1996; 74:1-7
26. Urhausen A, Scharhag J, Herrmann M, Kindermann W. Clinical significance of increased cardiac troponins T and I in participants of ultra-endurance events. Am J Cardiol 2004; 94:696-698
27. Vidotto C, Tschan H, Atamaniuk J, Pokan R, Bachl N, Muller MM. Responses of N-terminal pro-B type natriuretic peptide (NT-pro-BNP) and cardiac troponin I (cTnI) to competitive endurance exercise in recreational athletes. Int J Sports Med 2005; 26:645-650
28. Wang TJ, Larson MG, Levy D, Benjamin EJ, Leip EP, Omland T, Wolf PA, Vasan RS. Plasma natriuretic peptide levels and the risk of cardiovascular events and death. N Engl J Med 2004; 350:655-663
29. Whyte G, Stephens N, Senior R, George K, Shave R, Wilson M, Sharma S. Treat the patient not the blood test: The implications of an elevation in cardiac troponin following prolonged endurance exercise. Br J Sports Med 2007; 41:613-615
30. Wu AH, Valdes R Jr, Apple FS, Gornet T, Stone MA, Mayfield-Stokes S, Ingersoll-Stroubos AM, Wiler B. Cardiac troponin-T immunoassay for diagnosis of acute myocardial infarction. Clin Chem 1994; 40:900-907