Severe acquired aplastic anemia: Historical outcome of patients treated by allogeneic bone marrow transplantation from matched sibling donors. A study by the Spanish Group for Bone Marrow Transplantation in Children (GETMON);Aplasia medular grave adquirida: Evolución histórica de los resultados obtenidos con trasplante de progenitores hematopoyéticos de donante familiar. Estudio del Grupo Español para el Trasplante de Médula Ósea en Niños (GETMON)

Anales de Pediatria

Volumn 69, Issue 1, 2008, Pages 5-9

  Munoz Villa A ^a,k   Diaz De Heredia C ^b   Diaz Gonzalez M A ^c   Badell Serra, I ^d   Martinez Rubio A ^e   Gonzalez Valentin M A ^f   Dasi Carpio M A ^g   Gomez Perez P ^h   Bureo Dacal, E ⁱ   Olive Oliveras T ^b   Perez Hurtado J M ^j   Maldonado Regalado, M S ^a  

^a UNIVERSITY OF ALCALÁ   (Spain)

^b HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

^c HOSPITAL INFANTIL UNIVERSITARIO NIÑO JESÚS   (Spain)

^d HOSPITAL DE LA SANTA CREU I SANT PAU   (Spain)

^e HOSPITAL UNIVERSITARIO LA PAZ   (Spain)

^f HOSPITAL REGIONAL UNIVERSITARIO DE MÁLAGA   (Spain)

^g HOSPITAL UNIVERSITARIO LA FE   (Spain)

^h HOSPITAL UNIVERSITARIO REINA SOFÍA   (Spain)

ⁱ HOSPITAL UNIVERSITARIO MARQUÉS DE VALDECILLA   (Spain)

^j HOSPITAL UNIVERSITARIO VIRGEN DEL ROCÍO   (Spain)

^k HOSPITAL RAMÓN Y CAJAL   (Spain)

more..

Author keywords

Acquired aplastic anaemia; Haematopoietic stem cell transplantation; Immunosuppression

Indexed keywords

CYCLOPHOSPHAMIDE; CYCLOSPORIN; METHOTREXATE; THYMOCYTE ANTIBODY;

ADOLESCENT; ADULT; ALLOGENIC BONE MARROW TRANSPLANTATION; APLASTIC ANEMIA; ARTICLE; CHILD; CONTROLLED STUDY; FEMALE; GRAFT VERSUS HOST REACTION; HUMAN; IRRADIATION; MAJOR CLINICAL STUDY; MALE; SURVIVAL;

EID: 46849098229     PISSN: 16954033     EISSN: 16959531     Source Type: Journal    
DOI: 10.1157/13124211     Document Type: Article

References (20)

1. International Agranulocytosis and Aplastic Anemia Study Group. Incidence of aplastic anemia: The relevance of diagnostic criteria. Blood. 1989;70:1718-21.
2. Locasciulli A. Acquired aplastic anemia in children: Incidence, prognosis and treatment options. Pediatric Drugs. 2002;4:761-6.
3. Young NS, Calado RT, Scheinberg P. Current concepts in the pathophysiology and treatment of aplastic anemia. Blood. 2006;108:2506-19.
4. Horowitz MM. Current status of allogeneic bone marrow transplantation in acquired aplastic anemia. Semin Hematol. 2000;37:30-42.
5. Protocolo de estudio y tratamiento de la aplasia medular adquirida. AMA-2006. Sociedad Española de Hematología Pediátrica. Asociación Española de Pediatría.
6. Passweg JR, Pérez WS, Eapen M, Camitta BM, Gluckman E, Hinterberger W, et al. Bone marrow transplants from mismatched related and unrelated donors for severe aplastic anemia. Bone Marrow Transplant. 2006;37:641-9.
7. Kojima S, Horibe K, Inaba J, Yoshimi A, Takahashi Y, Kudo K, et al. Long-term outcome of acquired aplastic anemia in children: Comparison between immunosupressive therapy and bone marrow transplantation. Br J Haematol. 2000;111:321-8.
8. Ades L, Mary JY, Robin M, Ferry C, Porcher R, Esperou H, et al. Long-term outcome after bone marrow transplantation for severe aplastic anemia. Blood. 2004;103:2490-7.
9. Muñoz Villa A, Ortega Aramburu JJ, Bureo Dacal E, Badell Serra I, Madero López L, Olivé Oliveras T, et al. Trasplante alogénico de médula ósea en niños con aplasia medular grave adquirida. Resultados a largo plazo. An Esp Pediatr. 1999;50:29-32.
10. Locasculli A, Oneto R, Bacigalupo A, Socié G, Kothof E, Bekassy, A et al. Outcome of patients with acquired aplasia given first line bone marrow transplantation or immunosupressive treatment in the last decade: A report from the European Group for Blood and Marrow Transplantation. Haematologica. 2007;92:11-8.
11. McCann SR, Bacigalupo A, Gluckman E, Hinterberger W, Hows J, Ljungman P, et al. Graft rejection and second bone marrow transplants for acquired bone marrow aplasia. A report from the aplastic anemia working party of the European source. Bone Marrow Transplant. 1994;13:233-7.
12. Kahl C, Leisenring W, Deeg HJ, Chaucey TR, Flowers ME, Martin PJ, et al. Cyclophosphamide and antithymocyte globulin as conditioning for allogeneic bone marrow transplantation in patients with aplastic anemia: A long-term follow up. Br J Haematol. 2005;130:1718-21.
13. Bacigalupo A, Locatelli F, Lanino E, Marsh J, Socié G, Maury S, et al. Fludarabine, cyclophosphamyde and anti-thimocyte globulin for alternative transplants in acquired severe aplastic anemia: A report from the EBMT-SAA Working Party. Bone Marrow Transplant. 2005;36:947-50.
14. Pierga JY, Socié G, Gluckman E, Devierge A, Henry-Amar M, Bridier A, et al. Secondary solid malignan tumors occurring alter bone marrow transplantation foe severe aplastic anemia living thoraco-abdominal irradiation. Radiother Oncol. 1994;30:55-8.
15. Davies JK, Guinan EC. An update on the management of severe idiophatic aplastic anemia in children. Br J Haematol. 2007;136:549-64.
16. Storb R, Prentice RL, Thomas ED. Marrow transplantation for treatment of aplastic anemia. An analysis of factors associated with graft rejection. N Engl J Med. 1977;296:61-6.
17. Kobayashi R, Yabe H, Hara J, Morimoto A, Tsuchida M, Mugishima H et al. Preceding immunosuppressive therapy with antithymocyte globulin and ciclosporin increases the incidence of graft rejection in children with aplastic anemia who underwent allogeneic bone marrow transplantation from HLA-identical siblings. Br J Haematol. 2006;135:693-6.
18. Deeg HJ, Leisenring W, Nims J. Long-term outcome and quality of life after marrow transplantation for severe aplastic anemia. Blood. 1996;88:643.
19. Deeg HJ, Socié G, Schoch G, Henry-Amar M, Witherspoon RP, Devergie A, et al. Malignancies after bone marrow transplantation for aplastic anemia and Fanconi anemia: A joint Seattle and Paris analysis of results in 700 patients. Blood. 1996;87:386-92.
20. Ohga S, Ichino K, Goto K, Hattori S, Nomura A, Takada H, et al. Unrelated cord blood transplantation for severe aplastic anemia after a modified conditioning. Pediatr Transplant. 2006;10:497-500.