Serum leptin in first-trimester Down syndrome pregnancies

Prenatal Diagnosis

Volumn 28, Issue 6, 2008, Pages 475-477

  Hedley, Paula ^a   Christiansen, Michael ^a  

^a STATENS SERUM INSTITUT   (Denmark)

Author keywords

Aneuploidy; Down syndrome; Leptin; Placenta; Prenatal screening

Indexed keywords

CHORIONIC GONADOTROPIN BETA SUBUNIT; LEPTIN; LEPTIN RECEPTOR; PREGNANCY ASSOCIATED PLASMA PROTEIN A;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DOWN SYNDROME; FEMALE; FIRST TRIMESTER PREGNANCY; GESTATIONAL AGE; HUMAN; IMMUNOASSAY; NUTRITIONAL STATUS; PLACENTA; PRIORITY JOURNAL; PROTEIN EXPRESSION;

BIOLOGICAL MARKERS; DOWN SYNDROME; FEMALE; HUMANS; LEPTIN; LINEAR MODELS; PREGNANCY; PREGNANCY TRIMESTER, FIRST; PRENATAL DIAGNOSIS;

EID: 46749155969     PISSN: 01973851     EISSN: 10970223     Source Type: Journal    
DOI: 10.1002/pd.1998     Document Type: Article

References (16)

1. Ahima RS, Flier JS. 2000. Leptin. Annu Rev Physiol 62(1): 413-437.
2. Ashworth CJ, Hoggard N, Thomas L, Mercer JG, Wallace JM, Lea RG. 2000. Placental leptin. Rev Reprod 5(1): 18-24.
3. Catov JM, Patrick TE, Powers RW, Ness RB, Harger G, Roberts JM. 2007. Maternal leptin across pregnancy in women with small-for-gestational-age infants. Am J Obstet Gynecol 196: 558.e1-558.e8.
4. Christiansen M, Larsen SO. 2001. Precision of risk in multidimensional likelihood ratio based screening with first trimester screening for Down's syndrome as a special case. J Med Screen 8(2): 61-64.
5. +6 weeks in relation to the presence or absence of the fetal nasal bone on ultrasonography in chromosomally abnormal fetuses: an updated analysis of integrated ultrasound and biochemical screening. Prenat Diagn 25: 977-983.
6. Elmquist JK. 2000. Anatomic basis of leptin action in the hypothalamus. Front Horm Res 26: 21-41.
7. Hardie L, Trayhurn P, Abramovich D, Fowler P. 1997. Circulating leptin in women: a longitudinal study in the menstrual cycle and during pregnancy. Clin Endocrinol 47(1): 101-106.
8. Hendler I, Blackwell SC, Mehta SH, et al. 2005. The levels of leptin, adiponectin, and resistin in normal weight, and obese pregnant women with and without preeclampsia. Am J Obstet Gynecol 193: 979-983.
9. Henson MC, Castracane VD. 2000. Leptin in pregnancy. Biol Reprod 63(5): 1219-1228.
10. Margetic S, Gazzola C, Pegg GG, Hill RA. 2002. Leptin: a review of its peripheral actions and interactions. Int J Obes 26(11): 1407-1433.
11. Rizos D, Hassiakos D, Grigori-Kostaraki P, Sarandakou A, Botsis D, Salamalekis E. 2002. Maternal serum leptin concentration during the second trimester of pregnancy: association with fetal chromosomal abnormalities. Prenat Diagn 22(3): 221-225.
12. Senaris R, GarciaCaballero T, Casabiell X, et al. 1997. Synthesis of leptin in human placenta. Endocrinology 138(10): 4501-4504.
13. Stock SM, Bremme KA. 1998. Elevation of plasma leptin levels during pregnancy in normal and diabetic women. Metab Clin Exp 47(7): 840-843.
14. Tamás P, Sulyok E, Szabo I, et al. 1998. Changes of maternal serum leptin levels during pregnancy. Gynecol Obstet Invest 46(3): 169-171.
15. Tamura T, Goldenberg RL, Johnston KE, Cliver SP. 1998. Serum leptin concentrations during pregnancy and their relationship to fetal growth. Obstet Gynecol 91(3): 389-395.
16. Yang M-J. 2005. Interrelationship of maternal serum leptin, body mass index and gestational age. J Chin Med Assoc 68(10): 452-457.