Computer-based detection of neonatal changes to branching morphogenesis reveals different mechanisms of and predicts prostate enlargement in mice haplo-insufficient for bone morphogenetic protein 4

Journal of Pathology

Volumn 206, Issue 1, 2005, Pages 52-61

  Almahbobi, Ghanim ^a   Hedwards, Shelley ^a   Fricout, Gabriel ^b   Jeulin, Dominique ^b   Bertram, John F ^a   Risbridger, Gail P ^a,c  

^a MONASH UNIVERSITY   (Australia)

^b PSL RESEARCH UNIVERSITY   (France)

^c HUDSON INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

BMP4; Branching morphogenesis; Computer based analysis; Mouse model; Prostate enlargement

Indexed keywords

BONE MORPHOGENETIC PROTEIN 4;

ANIMAL TISSUE; ARTICLE; BRANCHING MORPHOGENESIS; COMPUTER ANALYSIS; CONTROLLED STUDY; HAPLOIDY; MALE; MOUSE; NEWBORN; NONHUMAN; ORGAN SIZE; ORGAN WEIGHT; PERINATAL DEVELOPMENT; PHENOTYPE; PRIORITY JOURNAL; PROSTATE HYPERTROPHY; PROSTATE VENTRAL LOBE;

ANIMALS; ANIMALS, NEWBORN; BONE MORPHOGENETIC PROTEINS; HOMOZYGOTE; IMAGE PROCESSING, COMPUTER-ASSISTED; IMAGING, THREE-DIMENSIONAL; MALE; MICE; MICE, MUTANT STRAINS; MICROSCOPY, CONFOCAL; MORPHOGENESIS; PROSTATE; PROSTATIC HYPERPLASIA;

EID: 18144410189     PISSN: 00223417     EISSN: None     Source Type: Journal    
DOI: 10.1002/path.1753     Document Type: Article

References (27)

1. Lamm MLG, Podlasek CA, Barnett DH, et al. Mesenchymal factor bone morphogenetic protein 4 restricts ductal budding and branching morphogenesis in the developing prostate. Dev Biol 2001; 232: 301-314.
2. Lung B, Cunha GR. Development of seminal vesicles and coagulating glands in neonatal mice. I. The morphogenetic effects of various hormonal conditions. Anat Rec 1981; 199: 73-88.
3. Sugimura Y, Cunha GR, Donjacour AA. Morphogenesis of ductal networks in the mouse prostate. Biol Reprod 1986; 34: 961-971.
4. Donjacour AA, Cunha GR. The effect of androgen deprivation on branching morphogenesis in the mouse prostate. Dev Biol 1988; 128: 1-14.
5. Hayashi N, Sugimura Y, Kawamura J, Donjacour AA, Cunha GR. Morphological and functional heterogeneity in the rat prostatic gland. Biol Reprod 1991; 45: 308-321.
6. Ruan W, Powell-Braxton L, Kopchick JJ, Kleinberg DL. Evidence that insulin-like growth factor I and growth hormone are required for prostate gland development. Endocrinology 1999; 140: 1984-1989.
7. vom Saal FS, Timms BG, Montano MM, et al. Prostate enlargement in mice due to fetal exposure to low doses of estradiol or diethylstilbestrol and opposite effects at high doses. Proc Natl Acad Sci U S A 1997; 94: 2056-2061.
8. Timms BG, Mohs TJ, Didio LJ. Ductal budding and branching patterns in the developing prostate. J Urol 1994; 151: 1427-1432.
9. Marker PC, Stephan JP, Lee J, Bald L, Mather JP, Cunha GR. Fucosyltransferase1 and H-type complex carbohydrates modulate epithelial cell proliferation during prostatic branching morphogenesis. Dev Biol 2001; 233: 95-108.
10. Timms BG, Petersen SL, vom Saal FS. Prostate gland growth during development is stimulated in both male and female rat fetuses by intrauterine proximity to female fetuses. J Urol 1999; 161: 1694-1701.
11. Lawson KA, Dunn NR, Roelen BA, et al. Bmp4 is required for the generation of primordial germ cells in the mouse embryo. Genes Dev 1999; 13: 424-436.
12. Hogan BL, Beddington RS, Constantini F, Lacy E. Manipulating the Mouse Embryo. Cold Spring Harbor Laboratory Press: Cold Spring Harbor, NY, 1994.
13. Jarred RA, Cancilla B, Prins GS, Thayer KA, Cunha GR, Risbridger GP. Evidence that estrogens directly alter androgen-regulated prostate development. Endocrinology 2000; 141: 3471-3477.
14. Almahbobi G, Hall PF. Indirect immunofluorescence modified to display two antigens with one light filter. Histochem J 1993; 25: 14-18.
15. Cullen-McEwen LA, Fricout G, Harper IS, Jeulin D, Bertram JF. Quantitation of 3D ureteric branching morphogenesis in cultured embryonic mouse kidney. Int J Dev Biol 2002; 46: 1049-1055.
16. Fricout G, Cullen-McEwen L, Harper IS, Jeulin D, Bertram JF. A quantitative method for analysing 3D branching in embryonic kidneys: development of a technique and preliminary data. Image Anal Stereol 2001; 20: 36-41.
17. Cruz-Orive LM, Howard CV. Estimating the length of a bounded curve in three dimensions using total vertical projections. J Microsc 1991; 163: 101-113.
18. Cancilla B, Jarred RA, Wang H, Mellor SL, Cunha GR, Risbridger GP. Regulation of prostate branching morphogenesis by activin a and follistatin. Dev Biol 2001; 237: 145-158.
19. Ko K, Theobald HM, Peterson RE. In utero and lactational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin in the C57BL/6J mouse prostate: lobe-specific effects on branching morphogenesis. Toxicol Sci 2002; 70: 227-237.
20. Weaver M, Yingling JM, Dunn NR, Bellusci S, Hogan BL. Bmp signaling regulates proximal-distal differentiation of endoderm in mouse lung development. Development 1999; 126: 4005-4015.
21. Miyazaki Y, Oshima K, Fogo A, Hogan BL, Ichikawa I. Bone morphogenetic protein 4 regulates the budding site and elongation of the mouse ureter. J Clin Invest 2000; 105: 863-873.
22. Jung HS, Francis-West PH, Widelitz RB, et al. Local inhibitory action of BMPs and their relationships with activators in feather formation: implications for periodic patterning. Dev Biol 1998; 196: 11-23.
23. Raatikainen-Ahokas A, Hytonen M, Tenhunen A, Sainio K, Sariola H. BMP-4 affects the differentiation of metanephric mesenchyme and reveals an early anterior-posterior axis of the embryonic kidney. Dev Dynam 2000; 217: 146-158.
24. Harris SE, Harris MA, Mahy P, Wozney J, Feng JQ, Mundy GR. Expression of bone morphogenetic protein messenger RNAs by normal rat and human prostate and prostate cancer cells. Prostate 1994; 24: 204-211.
25. Fisher CE, Michael L, Barnett MW, Davies JA. Erk MAP kinase regulates branching morphogenesis in the developing mouse kidney. Development 2001; 128: 4329-4338.
26. Crelin ES. Development of the lower respiratory system. Ciba Clin Symp 1975; 27: 3-28.
27. Hogan BL. Morphogenesis. Cell 1999; 96: 225-233.