FMRFamide-like peptides encoded on the flp-18 precursor gene activate two isoforms of the orphan Caenorhabditis elegans G-protein-coupled receptor Y58G8A.4 heterologously expressed in mammalian cells

Biopolymers - Peptide Science Section

Volumn 90, Issue 3, 2008, Pages 339-348

  Kubiak, Teresa M ^a   Larsen, Martha J ^a,b   Bowman, Jerry W ^a   Geary, Timothy G ^a,c   Lowery, David F ^a  

^a PFIZER INC   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

^c MCGILL UNIVERSITY   (Canada)

Author keywords

C. elegans; Calcium signaling; Flp 18; Orphan GPCR; Y58G8A.4

Indexed keywords

AMINATION; AMINO ACIDS; ANIMAL CELL CULTURE; CALCIUM; MAMMALS; ORGANIC ACIDS; PEPTIDES; PORT TERMINALS; PROTEINS;

AMINO ACID RESIDUES; AMINO-ACID SEQUENCES; ASCARIS SUUM; C-TERMINAL TAIL; C. ELEGANS; CAENORHABDITIS ELEGANS; CALCIUM MOBILIZATION; CALCIUM SIGNALING; CHINESE HAMSTER OVARY CELLS; FLP-18; FMRFAMIDE; G PROTEIN-COUPLED RECEPTOR; G-PROTEIN-COUPLED RECEPTORS; ISOFORMS; MAMMALIAN CELLS; NANO MOLAR; NEUROPEPTIDES; ORPHAN GPCR; RECEPTOR FUNCTIONS; Y58G8A.4;

AMINES;

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; CAENORHABDITIS ELEGANS PROTEIN; CALCIUM; CYCLIC AMP; G PROTEIN COUPLED RECEPTOR; NEUROPEPTIDE; RECOMBINASE; RECOMBINASE 18; UNCLASSIFIED DRUG; ISOPROTEIN; PHENYLALANYLMETHIONYLARGINYLPHENYLALANINAMIDE; RECEPTOR;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; ASCARIS SUUM; CAENORHABDITIS ELEGANS; CALCIUM MOBILIZATION; CALCIUM SIGNALING; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; FEMALE; GENE ACTIVATION; HETEROLOGOUS EXPRESSION; MAMMAL CELL; MOLECULAR CLONING; MOLECULAR RECOGNITION; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROCESSING; PROTEIN TARGETING; SIGNAL TRANSDUCTION; TEMPERATURE SENSITIVITY; ANIMAL; CHEMISTRY; CHO CELL; CRICETULUS; GENE; GENETICS; HAMSTER; METABOLISM; MOLECULAR GENETICS; PHYLOGENY; RADIOASSAY; SEQUENCE HOMOLOGY;

ASCARIS SUUM; CAENORHABDITIS ELEGANS; CRICETULUS GRISEUS; MAMMALIA;

AMINO ACID SEQUENCE; ANIMALS; CAENORHABDITIS ELEGANS; CHO CELLS; CRICETINAE; CRICETULUS; FMRFAMIDE; GENES, HELMINTH; MOLECULAR SEQUENCE DATA; PHYLOGENY; PROTEIN ISOFORMS; RADIOLIGAND ASSAY; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, INVERTEBRATE PEPTIDE; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 46749129840     PISSN: 00063525     EISSN: 10970282     Source Type: Journal    
DOI: 10.1002/bip.20850     Document Type: Article

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