Cloning, expression, purification and crystallization of the PR domain of human retinoblastoma protein-binding zinc finger protein 1 (RIZ1)

International Journal of Molecular Sciences

Volumn 9, Issue 6, 2008, Pages 943-950

  Sun, Wanpeng ^a   Geyer, C Ronald ^b   Yang, Jian ^a  

^a UNIVERSITY OF SASKATCHEWAN   (Canada)

^b UNIVERSITY OF SASKATCHEWAN   (Canada)

Author keywords

Affinity chromatography; Protein crystallization; Tumor suppressor; Yin Yang regulation; Zinc finger

Indexed keywords

METHYLTRANSFERASE; ONCOPROTEIN; RETINOBLASTOMA PROTEIN INTERACTING ZINC FINGER PROTEIN 1; RETINOBLASTOMA PROTEIN INTERACTING ZINC FINGER PROTEIN 2;

AMINO ACID SEQUENCE; ARTICLE; CANCER INHIBITION; CELL DIVISION; CELL FUNCTION; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLIZATION; ENZYME ACTIVITY; GENE OVEREXPRESSION; HUMAN; MOLECULAR CLONING; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; POLYMERASE CHAIN REACTION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; PROTEIN STRUCTURE; PROTO ONCOGENE; TUMOR SUPPRESSOR GENE; X RAY CRYSTALLOGRAPHY;

EID: 46749120937     PISSN: None     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms9060943     Document Type: Article

References (24)

1. Buyse, I. M.; Shao, G.; Huang, S. The retinoblastoma protein binds to RIZ, a zinc-finger protein that shares an epitope with the adenovirus E1A protein. Proc. Natl. Acad. Sci. USA 1995, 92, 4467-4471.
2. Buyse, I. M.; Huang, S. In vitro analysis of the E1A-homologous sequences of RIZ. J. Virol. 1997, 71, 6200-6203.
3. Buyse, I.M.; Takahashi, E.I.; Huang, S. Physical mapping of the retinoblastoma interacting zinc finger gene RIZ to D1S228 on chromosome 1p36. Genomics 1996, 34, 119-121.
4. Muraosa, Y.; Takahashi, K.; Yoshizawa, M.; Shibahara, S. cDNA cloning of a novel protein containing two zinc-finger domains that may function as a transcription factor for the human heme-oxygenase-1 gene. Eur. J. Biochem. 1996, 235, 471-479.
5. Juneja, S.; Lukeis, R.; Tan, L.; Cooper, I.; Szelag, G.; Parkin, J.D.; Ironside, P.; Garson, O.M. Cytogenetic analysis of 147 cases of non-Hodgkin's lymphoma: non-random chromosomal abnormalities and histological correlations. Br. J. Haemotol. 1990, 76, 231-237.
6. Whang-Peng, J.; Knutsen, T.; Jaffe, E.S.; Steinberg, S.M.; Raffeld, M.; Zhao, W.P.; Duffey, P.; Condron, K.; Yano, T.; Longo D.L. Sequential analysis of 43 patients with non-Hodgkin's lymphoma: clinical correlations with cytogenetic, histologic, immunophenotyping, and molecular studies. Blood 1995, 85, 203-216.
7. Cigudosa, J.C.; Parsa, N.Z.; Louie, D.C.; Filippa, D.A.; Jhanwar, S.C.; Johansson, B.; Mitelman, F.; Chaganti, R.S. Cytogenetic analysis of 363 consecutively ascertained diffuse large B-cell lymphomas. Genes Chromosomes Cancer 1999, 25, 123-133.
8. Dave, B.J.; Hess, M.M.; Pickering, D.L.; Zaleski, D.H.; Pfeifer, A.L.; Weisenburger, D.D.; Armitage, J.O.; Sanger, W.G. Rearrangements of chromosome band 1p36 in non-Hodgkin's lymphoma. Clin. Cancer Res. 1999, 5, 1401-1409.
9. Sasaki, O.; Meguro, K.; Tohmiya, Y.; Funato, T.; Shibahara, S.; Sasaki, T. Altered expression of retinoblastoma protein-interacting zinc finger gene, RIZ, in human leukaemia. Br. J. Haematol. 2002, 119, 940-948.
10. Liu, L.; Shao, G.; Steele-Perkins, G.; Huang, S. The retinoblastoma interacting zinc finger gene RIZ produces a PR domain-lacking product through an internal promoter. J. Biol. Chem. 1997, 272, 2984-2991.
11. Huang, S.; Shao, G.; Liu, L. The PR domain of the Rb-binding zinc finger protein RIZ1 is a protein binding interface and is related to the SET domain functioning in chromatin-mediated gene expression. J. Biol. Chem. 1998, 273, 15933-15939.
12. Jiang, G.; Huang, S. Adenovirus expressing RIZ1 in tumor suppressor gene therapy of microsatellite-unstable colorectal cancers. Cancer Res. 2001, 61, 1796-1798.
13. Du, Y.; Carling, T.; Fang, W.; Piao, Z.; Sheu, J.C.; Huang, S. Hypermethylation in human cancers of the RIZ1 tumor suppressor gene, a member of a histone/protein methyltransferase superfamily. Cancer Res. 2001, 61, 8094-8099.
14. Deng, Q.; Huang, S. PRDM5 is silenced in human cancers and has growth suppressive activities. Oncogene 2004, 17, 4903-4910.
15. Mori, N.; Morosetti, R.; Spira, S.; Lee, S.; Ben-Yehuda, D.; Schiller, G.; Landolfi, R.; Mizoguchi, H.; Koeffler, H.P. Chromosome band 1p36 contains a putative tumor suppressor gene important in the evolution of chronic myelocytic leukemia. Blood 1998, 92, 3405-3409.
16. He, L.; Yu, J.X.; Liu, L.; Buyse, I.M.; Wang, M.S.; Yang, Q.C.; Nakagawara, A.; Brodeur, G.M.; Shi, Y.E.; Huang, S. RIZ1, but not the alternative RIZ2 product of the same gene, is underexpressed in breast cancer, and forced RIZ1 expression causes G2-M cell cycle arrest and/or apoptosis. Cancer Res. 1998, 58, 4238-4244.
17. Jiang, G.; Liu, L.; Buyse, I.M.; Simon, D.; Huang, S. Decreased RIZ1 expression but not RIZ2 in hepatoma and suppression of hepatoma tumorigenicity by RIZ1. Int. J. Cancer. 1999, 83, 541-546.
18. Chadwick, R.B.; Jiang, G.L.; Bennington, G.A.; Yuan, B.; Johnson, C.K.; Stevens, M.W.; Niemann, T.H.; Peltomaki, P.; Huang, S.; de la Chapelle, A. Candidate tumor suppressor RIZ is frequently involved in colorectal carcinogenesis. Proc. Natl. Acad. Sci. USA 2000, 97, 2662-2667.
19. Tam, W.; Gomez, M.F.; Chadburn, A.; Knowles, D.M.; Houldsworth, J. Lack of A563G (I188V) missense mutation in RIZ/ PRDM2 in human diffuse large B-cell lymphomas. Genes Chromosomes Cancer 2007, 46, 416-418.
20. Sasaki, O.; Meguro, K.; Tohmiya, Y.; Funato, T.; Shibahara, S.; Sasaki, T. Nucleotide alteration of retinoblastoma protein-interacting zinc finger gene, RIZ, in human leukemia. Tohoku J. Exp. Med. 2002, 196, 193-201.
21. Canote, R.; Du, Y.; Carling, T.; Tian, F.; Peng, Z.; Huang, S. The tumor suppressor gene RIZ in cancer gene therapy (review). Oncol. Rep. 2002, 9, 57-60.
22. Derunes, C.; Briknarová, K.; Geng, L.; Li, S.; Gessner, C.R.; Hewitt, K.; Wu, S.; Huang, S.; Woods, V.I. Jr.; Ely, K.R. Characterization of the PR domain of RIZ1 histone methyltransferase. Biochem. Biophys. Res. Commun. 2005, 333, 925-934.
23. Kim, K.C.; Huang, S. Histone methyltransferases in tumor suppression. Cancer Biol. Ther. 2003, 2, 491-499.
24. Briknarová, K.; Zhou, X.; Satterthwait, A.; Hoyt, D.W.; Ely, K.R.; Huang S. Structural studies of the SET domain from RIZ1 tumor suppressor. Biochem. Biophys. Res. Commun. 2008, 366, 807-813.