Non-invasive restrained ECG recording in conscious small rodents: A new tool for cardiac electrical activity investigation

Pflugers Archiv European Journal of Physiology

Volumn 454, Issue 1, 2007, Pages 165-171

  Mongue Din, H ^a   Salmon, A ^a   Fiszman, M Y ^a   Fromes, Y ^a,b  

^a PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^b SAINT JOSEPH HOSPITAL   (France)

Author keywords

Cardiac phenotype; Electrocardiography; Electrophysiology; Hamster; Mouse; Restraints

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ELECTROCARDIOGRAM; HAMSTER; HEART CONTRACTION; HEART ELECTROPHYSIOLOGY; METHODOLOGY; MONITORING; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RR INTERVAL; SEDATION; TELEMETRY;

ANIMALS; ANIMALS, LABORATORY; ANIMALS, NEWBORN; CARDIOLOGY; CRICETINAE; ELECTROCARDIOGRAPHY; ELECTROPHYSIOLOGY; EQUIPMENT DESIGN; HEART RATE; MESOCRICETUS; MICE; MICE, INBRED STRAINS; RESTRAINT, PHYSICAL; TELEMETRY;

EID: 33847678147     PISSN: 00316768     EISSN: 14322013     Source Type: Journal    
DOI: 10.1007/s00424-006-0197-8     Document Type: Article

References (18)

1. Berul CI, Aronovitz MJ, Wang PJ, Mendelsohn ME (1996) In vivo cardiac electrophysiology studies in the mouse. Circulation 94(10):2641-2648
2. Berul CI, Christe ME, Aronovitz MJ, Seidman CE, Seidman JG, Mendelsohn ME (1997) Electrophysiological abnormalities and arrhythmias in alpha MHC mutant familial hypertrophic cardiomyopathy mice. J Clin Invest 99(4):570-576
3. Chu V, Otero JM, Lopez O, Morgan JP, Amende I, Hampton TG (2001) Method for non-invasively recording electrocardiograms in conscious mice. BMC Physiol 1:6
4. Doevendans PA, Daemen MJ, de Muinck ED, Smits JF (1998) Cardiovascular phenotyping in mice. Cardiovasc Res 39(1):34-49
5. Gehrmann J, Hammer PE, Maguire CT, Wakimoto H, Triedman JK, Berul CI (2000) Phenotypic screening for heart rate variability in the mouse. Am J Physiol Heart Circ Physiol 279(2):H733-H740
6. Goldbarg AN, Hellerstein HK, Bruell JH, Daroczy AF (1968) Electrocardiogram of the normal mouse, Mus musculus: general considerations and genetic aspects. Cardiovasc Res 2(1):93-99
7. Hamlin RL, Kijtawornrat A, Keene BW, Hamlin DM (2003) QT and RR intervals in conscious and anesthetized guinea pigs with highly varying RR intervals and given QTc-lengthening test articles. Toxicol Sci 76(2):437-442
8. Hongo M, Ryoke T, Ross J (1997) Animal models of heart failure-recent developments and perspectives. Trends Cardiovasc Med 7(5):161-167
9. James JF, Hewett TE, Robbins J (1998) Cardiac physiology in transgenic mice. Circ Res 82(4):407-415
10. Kirchhof P, Fabritz L, Fortmuller L, Matherne GP, Lankford A, Baba HA, Schmitz W, Breithardt G, Neumann J, Boknik P (2003) Altered sinus nodal and atrioventricular nodal function in freely moving mice overexpressing the A1 adenosine receptor. Am J Physiol Heart Circ Physiol 285(1):H145-H153
11. Kramer K, Kinter L, Brockway BP, Voss HP, Remie R, Van Zutphen BL (2001) The use of radiotelemetry in small laboratory animals: recent advances. Contemp Top Lab Anim Sci 40(1):8-16
12. Kramer K, Kinter LB (2003) Evaluation and applications of radiotelemetry in small laboratory animals. Physiol Genomics 13(3):197-205
13. Kramer K, van Acker SA, Voss HP, Grimbergen JA, van der Vijgh WJ, Bast A (1993) Use of telemetry to record electrocardiogram and heart rate in freely moving mice. J Pharmacol Toxicol Methods 30(4):209-215
14. Mitchell GF, Jeron A, Koren G (1998) Measurement of heart rate and Q-T interval in the conscious mouse. Am J Physiol 274(3 Pt 2):H747-H751
15. Robineau P (1988) A simple method for recording electrocardiograms in conscious, unrestrained rats. J Pharmacol Methods 19(2):127-133
16. Royer A, van Veen TA, Le Bouter S, Marionneau C, Griol-Charhbili V, Leoni AL, Steenman M, van Rijen HV, Demolombe S, Goddard CA, Richer C, Escoubet B, Jarry-Guichard T, Colledge WH, Gros D, de Bakker JM, Grace AA, Escande D, Charpentier F (2005) Mouse model of SCN5A-linked hereditary Lenegre's disease: age-related conduction slowing and myocardial fibrosis. Circulation 111(14):1738-1746
17. Wang L, Swirp S, Duff H (2000) Age-dependent response of the electrocardiogram to K(+) channel blockers in mice. Am J Physiol Cell Physiol 278(1):C73-C80
18. Wehrens XH, Kirchhoff S, Doevendans PA (2000) Mouse electrocardiography: an interval of thirty years. Cardiovasc Res 45(1):231-237