Endothelin-1 (ET-1) is increased in rat retina after crushing optic nerve

Current Eye Research

Volumn 33, Issue 7, 2008, Pages 611-620

  Oku, Hidehiro ^a   Fukuhara, Masayuki ^a   Kurimoto, Takuji ^b   Okuno, Takashi ^a   Sugiyama, Tetsuya ^a   Ikeda, Tsunehiko ^a  

^a OSAKA MEDICAL COLLEGE   (Japan)

^b HYOGO COLLEGE OF MEDICINE   (Japan)

Author keywords

Endothelin; ETA and ETB receptors; Optic nerve crush; Radioimmunoassay; Retina

Indexed keywords

ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; ENDOTHELIN B RECEPTOR; MESSENGER RNA;

ANALYSIS OF VARIANCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; IMMUNOHISTOCHEMISTRY; MALE; NERVE CRUSH; NONHUMAN; OPTIC NERVE INJURY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIOIMMUNOASSAY; RAT; REAL TIME POLYMERASE CHAIN REACTION; RETINA; RETINA GANGLION CELL; RETINA INNER PLEXIFORM LAYER; RETINA NERVE CELL; STUDENT T TEST; WISTAR RAT;

ANIMALS; CELL COUNT; ENDOTHELIN-1; IMMUNOENZYME TECHNIQUES; MALE; OPTIC NERVE INJURIES; RADIOIMMUNOASSAY; RATS; RATS, WISTAR; RECEPTOR, ENDOTHELIN A; RECEPTOR, ENDOTHELIN B; RETINA; RETINAL GANGLION CELLS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; UP-REGULATION;

EID: 46749109195     PISSN: 02713683     EISSN: 14602202     Source Type: Journal    
DOI: 10.1080/02713680802213614     Document Type: Article

References (55)

1. Yanagisawa M, Kurihara H, Kimura S, Tomobe Y, Kobayashi M, Mitsui Y, Yazaki Y, Goto K, Masaki T. A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature. 1988;332:411-415.
2. Koyama Y, Ishibashi T, Hayata K, Baba A. Endothelins modulate dibutyryl cAMP-induced stellation of cultured astrocytes. Brain Res. 1993;600:81-88.
3. Koyama Y, Tsujikawa K, Matsuda T, Baba A. Endothelin-1 stimulates glial cell line-derived neurotrophic factor expression in cultured rat astrocytes. Biochem Biophys Res Commun. 2003;303:1101-1105.
4. Stanimirovic DB, Ball R, Mealing G, Morley P, Durkin JP. The role of intracellular calcium and protein kinase C in endothelin-stimulated proliferation of rat type I astrocytes. Glia. 1995;15:119-130.
5. Rogers SD, Demaster E, Catton M, Ghilardi JR, Levin LA, Maggio JE, Mantyh PW. Expression of endothelin-B receptors by glia in vivo is increased after CNS injury in rats, rabbits, and humans. Exp Neurol. 1997;145:180-195.
6. Rogers SD, Peters CM, Pomonis JD, Hagiwara H, Ghilardi JR, Mantyh PW. Endothelin-B receptors are expressed by astrocytes and regulate astrocyte hypertrophy in the normal and injured CNS. Glia. 2003;41:180-190.
7. Blomstrand F, Giaume C, Hansson E, Ronnback L. Distinct pharmacological properties of ET-1 and ET-3 on astroglial gap junctions and Ca(2+) signaling. Am J Physiol. 1999;277:C616-627.
8. Blomstrand F, Venance L, Siren AL, Ezan P, Hanse E, Glowinski J, Ehrenreich H, Giaume C. Endothelins regulate astrocyte gap junctions in rat hippocampal slices. Eur J Neurosci. 2004;19:1005-1015.
9. MacCumber MW, Jampel HD, Snyder SH. Ocular effects of the endothelins: abundant peptides in the eye. Arch Ophthalmol. 1991;107:707-709.
10. MacCumber MW, D'Anna SA. Endothelin receptor-binding subtypes in the human retina and choroid. Arch Ophthalmol. 1994;112:1231-1235.
11. de Juan JA, Moya FJ, Fernandez-Cruz A, Fernandez-Durango R. Identification of endothelin receptor subtypes in rat retina using subtype-selective ligands. Brain Res. 1995;690:25-33.
12. Ripodas A, de Juan JA, Roldan-Pallares M, Bernal R, Moya J, Chao M, Lopez A, Fernandez-Cruz A, Fernandez-Durango R. Localisation of endothelin-1 mRNA expression and immunoreactivity in the retina and optic nerve from human and porcine eye. Evidence for endothelin-1 expression in astrocytes. Brain Res. 2001;912:137-143.
13. Prasanna G, Narayan S, Krishnamoorthy RR, Yorio T. Eyeing endothelins: A cellular perspective. Mol Cell Biochem. 2003;253:71-88.
14. Torbidoni V, Iribarne M, Ogawa L, Prasanna G, Suburo AM. Endothelin-1 and endothelin receptors in light-induced retinal degeneration. Exp Eye Res. 2005;81:265-275.
15. Rattner A, Nathans J. The genomic response to retinal disease and injury: Evidence for endothelin signaling from photoreceptors to glia. J Neurosci. 2005;25:4540-4549.
16. Yagami T, Ueda K, Asakura K, Kuroda T, Hata S, Sakaeda T, Kambayashi Y, Fujimoto M. Effects of endothelin-B receptor agonists on amyloid beta protein (25-35)-induced neuronal cell death. Brain Res. 2002;948:72-81.
17. Siren AL, Lewczuk P, Hasselblatt M, Dembowski C, Schilling L, Ehrenreich H. Endothelin-B receptor deficiency augments neuronal damage upon exposure to hypoxia-ischemia in vivo. Brain Res. 2002;945:144-149.
18. Krishnamoorthy R, Dauphin R, Prasanna G, Johnson C, Yorio T. Endothelin-1 acts through endothelin B (ETB) receptors to mediate apoptosis of rat retinal ganglion cells. Invest Ophthalmol Vis Sci. 2005;46:E-Abstract 4656.
19. Kobayashi T, Oku H, Fukuhara M, Kojima S, Komori A, Ichikawa M, Katsumura K, Kobayashi M, Sugiyama T, Ikeda T. Endothelin-1 enhances glutamate-induced retinal cell death, possibly through ETA receptors. Invest Ophthalmol Vis Sci. 2005;46:4684-4690.
20. Tan O, Lin G, Lu AT, Varma R, Huang D. Advanced imaging for glaucoma study group. Mapping of macular substructures with optical coherence tomography for glaucoma diagnosis. Ophthalmology. 2008;115:949-956.
21. Ahmed F, Brown KM, Stephan DA, Morrison JC, Johnson EC, Tomarev SI. Microarray analysis of changes in mRNA levels in the rat retina after experimental elevation of intraocular pressure. Invest. Ophthalmol. Vis. Sci. 2004;45:1247-1258.
22. Ju KR, Kim HS, Kim JH, Lee NY, Park CK. Retinal glial cell responses and Fas/FasL activation in rats with chronic ocular hypertension. Brain Res. 2006;1122:209-221.
23. Berkelaar M, Clarke DB, Wang YC, Bray GM, Aguayo AJ. Axotomy results in delayed death and apoptosis of retinal ganglion cells in adult rats. J Neurosci. 1994;14:4368-4374.
24. Garcia-Valenzuela E, Gorczyca W, Darzynkiewicz Z, Sharma SC. Apoptosis in adult retinal ganglion cells after axotomy. J Neurobiol. 1994;25:431-438.
25. Isenmann S, Wahl C, Krajewski S, Reed JC, Bahr M. Up-regulation of Bax protein in degenerating retinal ganglion cells precedes apoptotic cell death after optic nerve lesion in the rat. Eur J Neurosci. 1997;9:1763-1772.
26. Yoles E, Schwartz M. Elevation of intraocular glutamate levels in rats with partial lesion of the optic nerve. Arch Ophthalmol. 1998;116:906-910.
27. Berry M, Carlile J, Hunter A. Peripheral nerve explants grafted into the vitreous body of the eye promote the regeneration of retinal ganglion cell axons severed in the optic nerve. J Neurocytol. 1996;25:147-170.
28. Kurimoto T, Ishii M, Tagami Y, Nishimura M, Miyoshi T, Tsukamoto Y, Mimura O. Xylazine promotes axonal regeneration in the crushed optic nerve of adult rats. Neuroreport. 2006;17:1525-1529.
29. Panagis L, Thanos S, Fischer D, Dermon CR. Unilateral optic nerve crush induces bilateral retinal glial cell proliferation. Eur J Neurosci. 2005;21:2305-2309.
30. Mey J, Thanos S. Intravitreal injections of neurotrophic factors support the survival of axotomized retinal ganglion cells in adult rats in vivo. Brain Res. 1993;602:304-317.
31. Winkler BS. The electroretinogram of the isolated rat retina. Vision Res. 1972;12:1183-1198.
32. de Juan JA, Moya FJ, Garcia de Lacoba M, Fernandez-Cruz A, Fernandez-Durango, R. Identification and characterization of endothelin receptor subtype B in rat retina. J Neurochem. 1993;61:1113-1119.
33. Chakrabarti S, Gan XT, Merry A, Karmazyn M, Sima AA. Augmented retinal endothelin-1, endothelin-3, endothelin-A, and endothelin-B gene expression in chronic diabetes. Curr Eye Res. 1998;17:301-307.
34. Deng D, Evans T, Mukherjee K, Downey D, Chakrabarti S. Diabetes-induced vascular dysfunction in the retina: Role of endothelins. Diabetologia. 1999;42:1228-1234.
35. de Juan JA, Moya FJ, Ripodas A, Bernal R, Fernandez-Cruz A, Fernandez-Durango R. Changes in the density and localization of endothelin receptors in the early stages of rat diabetic retinopathy and the effect of insulin treatment. Diabetologia. 2000;43:773-785.
36. Noske W, Hensen J, Wiederholt M. Endothelin-like immunoreactivity in aqueous humor of patients with primary open-angle glaucoma and cataract. Graefes Arch Clin Exp Ophthalmol. 1997;235:551-552.
37. Tezel G, Kass MA, Kolker AE, Becker B, Wax MB. Plasma and aqueous humor endothelin levels in primary open-angle glaucoma. J Glaucoma. 1997;6:83-89.
38. Kallberg ME, Brooks DE, Garcia-Sanchez GA, Komaromy AM, Szabo NJ, Tian L. Endothelin-1 levels in the aqueous humor of dogs with glaucoma. J Glaucoma. 2002;11:105-109.
39. Prasanna G, Hulet C, Desai D, Krishnamoorthy RR, Narayan S, Brun AM, Suburo AM, Yorio T. Effect of elevated intraocular pressure on endothelin-1 in a rat model of glaucoma. Pharmacol Res. 2005;51:41-50.
40. Stokely ME, Brady ST, Yorio T. Effects of endothelin-1 on components of anterograde axonal transport in optic nerve. Invest Ophthalmol Vis Sci. 2002;43:3223-3230.
41. Wang X, Baldridge WH, Chauhan BC. Acute endothelin-1 application induces reversible fast axonal transport blockade in adult rat optic nerve. Invest Ophthalmol Vis Sci. 2008;49:961-967.
42. Prasanna G, Krishnamoorthy R, Clark AF, Wordinger RJ, Yorio T. Human optic nerve head astrocytes as a target for endothelin-1. Invest Ophthalmol Vis Sci. 2002;43:2704-2713.
43. Yorio T, Krishnamoorthy R, Prasanna G. Endothelin: Is it a contributor to glaucoma pathophysiology? J Glaucoma. 2002;11:259-270.
44. Yamashita K, Niwa M, Kataoka Y, Shigematsu K, Himeno A, Tsutsumi K, Nakano-Nakashima M, Sakurai-Yamashita Y, Shibata S, Taniyama K. Microglia with an endothelin ETB receptor aggregate in rat hippocampus CA1 subfields following transient forebrain ischemia. J Neurochem. 1994;63:1042-1051.
45. Hasselblatt M, Lewczuk P, Löffler BM, Kamrowski-Kruck H, von Ahsen N, Sirén AL, Ehrenreich H. Role of the astrocytic ET(B) receptor in the regulation of extracellular endothelin-1 during hypoxia. Glia. 2001;34:18-26.
46. Lau J, Dang M, Hockmann K, Ball AK. Effects of acute delivery of endothelin-1 on retinal ganglion cell loss in the rat. Exp Eye Res. 2006;82:132-145.
47. Bush RA, Williams TP. The effect of unilateral optic nerve section on retinal light damage in rats. Exp Eye Res. 1991;52:139-153.
48. Kostyk SK, D'Amore PA, Herman IM, Wagner JA. Optic nerve injury alters basic fibroblast growth factor localization in the retina and optic tract, Part 2. J Neurosci. 1994;14:1441-1449.
49. Chun MH, Ju WK, Kim KY, Lee MY, Hofmann HD, Kirsch M, Oh SJ. Upregulation of ciliary neurotrophic factor in reactive Muller cells in the rat retina following optic nerve transection. Brain Res. 2000;868:358-362.
50. Ju WK, Kim KY, Lee MY, Hofmann HD, Kirsch M, Cha JH, Oh SJ, Chun MH. Up-regulated CNTF plays a protective role for retrograde degeneration in the axotomized rat retina. Neuroreport. 2000;11:3893-3896.
51. Martin A, Hofmann HD, Kirsch M. Glial reactivity in ciliary neurotrophic factor-deficient mice after optic nerve lesion. J Neurosci. 2003;23:5416-5424.
52. Casson RJ, Chidlow G, Wood JP, Vidal-Sanz M, Osborne NN. The effect of retinal ganglion cell injury on light-induced photoreceptor degeneration. Invest Ophthalmol Vis Sci. 2004;45:685-693.
53. Liu X, Adler R, Campochiaro PA, Zack DJ. Time course analysis of retinal transcriptome changes following intravitreal injection of CNTF, BDNF, and FGF-2. Invest Ophthalmol Vis Sci. 2007;48:E-Abstract 1348.
54. Narayan S, Prasanna G, Krishnamoorthy RR, Zhang X, Yorio T. Endothelin-1 synthesis and secretion in human retinal pigment epithelial cells (ARPE-19): Differential regulation by cholinergics and TNF-alpha. Invest Ophthalmol Vis Sci. 2003;44:4885-4494.
55. Wang L, Fortune B, Cull G, Dong J, Cioffi GA. Endothelin B receptor in human glaucoma and experimentally induced optic nerve damage. Arch Ophthalmol. 2006;124:717-724.