Localisation of endothelin-1 mRNA expression and immunoreactivity in the retina and optic nerve from human and porcine eye. Evidence for endothelin-1 expression in astrocytes

Brain Research

Volumn 912, Issue 2, 2001, Pages 137-143

  Ripodas, Ainhoa ^a   De Juan, Jose Angel ^a   Roldán Pallarés, Manuela ^a   Bernal, Rosa ^a   Moya, José ^b   Chao, Montserrat ^a   López, Araceli ^a   Fernández Cruz, Arturo ^a   Fernández Durango, Raquel ^a  

^a HOSPITAL CLÍNICO SAN CARLOS   (Spain)

^b NONE

Author keywords

Astrocyte; Endothelin; ETA and ETB receptors; Human and porcine retina and optic nerve

Indexed keywords

ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; ENDOTHELIN B RECEPTOR; GLIAL FIBRILLARY ACIDIC PROTEIN; MESSENGER RNA;

ADULT; AGED; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CLINICAL ARTICLE; CONTROLLED STUDY; EYE; FEMALE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; IN SITU HYBRIDIZATION; MALE; NERVE FIBER; NONHUMAN; OPTIC NERVE; PHOTORECEPTOR; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETINA; RETINA BIPOLAR GANGLION CELL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SWINE; TISSUE DISTRIBUTION;

EID: 0035823359     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(01)02731-7     Document Type: Article

References (43)

1. Cloning and expression of a cDNA encoding an endothelin receptor
2. Growth regulatory properties of endothelins
3. The in vivo effect of endothelins on retinal circulation in nondiabetic and diabetic rats
4. Augmented retinal endothelin-1, endothelin-3, endothelin A and endothelin B gene expression in chronic diabetes
5. The effect of endothelin-1 on the retinal microvascular pericyte
6. Single step method of RNA isolation by guanidium thiocyanate-phenol-cloroform extraction
7. B) in rat retina
8. Identification of receptor subtypes in rat retina using subtype-selective ligands
9. Changes in the density and localisation of endothelin receptors in the early stages of rat diabetic retinopathy and the effect of insulin treatment
10. The membranes of cultured rat brain astrocytes contain endothelin-converting enzyme activity
11. A vasoactive peptide, endothelin-3, is produced by and specifically binds to primary astrocytes
12. Endothelin receptor blockade prevents augmented extracellular matrix component mRNA expression and capillary basement membrane thickening in the retina of diabetic and galactose-fed rats
13. Messenger RNAs encoding the natriuretic peptides and their receptors are expressed in the eye
14. Increased immunoreactive endothelin-1 (ET-1) levels in the subretinal fluid in proliferative vitreoretinopathy
15. Topographical localisation of endothelin mRNA and peptide immunoreactivity in neurones of the human brain
16. Contraction of extracellular matrix by differentiated retinal pigment epithelial cells, inducers and inhibitors
17. Autoradiographic evidence for endothelin receptors on astrocytes in cultures of rat cerebellum, brainstem and spinal cord
18. Cloning and expression of human endothelin receptor cDNA
19. The human endothelin family: Three structurally and pharmacologically distinct isopeptides predicted by three separate genes
20. Expression of vasoconstrictor endothelin in the human central nervous system
21. Ocular effect of endothelin
22. Endothelin receptor-binding subtypes in the human retina and choroid
23. Endothelin in brain: Receptors, mitogenesis, and biosynthesis in glial cells
24. Astrocytes are target cells for endothelins and sarafotoxin
25. Endothelium-dependent regulation of the ophthalmic microcirculation in the perfused porcine eye
26. Müller cells changes in human diabetic retinopathy
27. Endothelin peptides in brain diseases
28. An endothelin-1 induced model of chronic optic nerve ischemia in rhesus monkeys
29. Molecular cloning of a non-isopeptide-selective human endothelin receptor
30. Expression and localisation of endothelin-1 and endothelin receptors in human meningioma. Evidence for a role in tumoral growth
31. Effects of endothelin on cultured bovine retinal microvascular pericytes
32. Identification of endothelin receptor subtypes in rat ciliary body using subtype-selective ligands
33. Cloning of a cDNA encoding a non isopeptide selective subtype of endothelin receptor
34. Molecular characterisation of endothelin receptor
35. Endothelin evokes efflux of glutamate in cultures of rat astrocytes
36. Endothelin-like immunoreactivity and receptor binding in the choroid and retina
37. mRNA localisation in neurones: A multipurpose mechanism?
38. Regulation of retinal hemodynamics in diabetic rats by increased expression and action of endothelin-1
39. RNA. Whither goest thou?
40. Endothelin-1 and endothelin-3 release EDRF from isolated perfused arterial vessel of the rat and rabbit
41. An immunohistochemical study of endothelin-1 in the human eye
42. A novel potent vasoconstrictor peptide produced by endothelial cells
43. Microglia with an endothelin ETB receptor aggregate in rat hippocampus CA1 subfields following transient forebrain ischemia