Genotoxic activation of 2-phenylbenzotriazole-type compounds by human cytochrome P4501A1 and N-acetyltransferase expressed in Salmonella typhimurium umu strains

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 654, Issue 1, 2008, Pages 52-57

  Oda, Yoshimitsu ^a   Watanabe, Tetsushi ^b   Terao, Yoshiyasu ^c   Nukaya, Haruo ^c   Wakabayashi, Keiji ^d  

^a OSAKA PREFECTURAL INSTITUTE OF PUBLIC HEALTH   (Japan)

^b KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

^c UNIVERSITY OF SHIZUOKA   (Japan)

^d NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

Author keywords

Genotoxicity; Human cytochrome P4501A1; O Acetyltransferase; PBTA type compounds; SOS umu assay

Indexed keywords

2 [2 (ACETYLAMINO) 4 (DIALLYLAMINO) 5 METHOXYPHENYL] 5 AMINO 7 BROMO CHLORO 2H BENZOTRIAZOLE; 2 [2 (ACETYLAMINO) 4 (DIETHYLAMINO) 5 METHOXYPHENYL] 5 AMINO 7 BROMO 4 CHLORO 2H BENZOTRIAZOLE; 2 [2 (ACETYLAMINO) 4 [BIS(2 HYDROXYETHYL)AMINO] 5 METHOXYPHENYL] 5 AMINO 7 BROMO 4 CHLORO 2H BENZOTRIAZOLE; 2 [2 (ACETYLAMINO) 4 AMINO 5 METHOXYPHENYL] 5 AMINO 7 BROMO 4 CHLORO 2H BENZOTRIAZOLE; 2 PHENYLBENZOTRIAZOLE DERIVATIVE; ACYLTRANSFERASE; ALPHA NAPHTHOFLAVONE; ARYLAMINE ACETYLTRANSFERASE; BENZOTRIAZOLE DERIVATIVE; COMPLEMENTARY DNA; CYTOCHROME P450 1A1; DYE; MUTAGENIC AGENT; RECOMBINANT CYTOCHROME P450 1A1; RECOMBINANT CYTOCHROME P450 1A2; RECOMBINANT CYTOCHROME P450 3A4; RECOMBINANT ENZYME; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE FERRIHEMOPROTEIN REDUCTASE; WATER;

ACETYLATION; ARTICLE; BACTERIAL STRAIN; CATALYSIS; CHEMICAL STRUCTURE; COTTON; DOMESTIC WASTE; GENE; GENE EXPRESSION; GENOTOXICITY; HUMAN; JAPAN; METABOLIC ACTIVATION; NONHUMAN; PLANT; PRIORITY JOURNAL; RAT; SALMONELLA TYPHIMURIUM; TEXTILE; TEXTILE INDUSTRY; UMUC GENE;

ANIMALS; ARYLAMINE N-ACETYLTRANSFERASE; BENZOFLAVONES; CATALYSIS; CYTOCHROME P-450 CYP1A1; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION; HUMANS; ISOENZYMES; MOLECULAR STRUCTURE; MUTAGENS; RATS; RECOMBINANT PROTEINS; SALMONELLA TYPHIMURIUM; SOS RESPONSE (GENETICS); STRUCTURE-ACTIVITY RELATIONSHIP; TRIAZOLES;

BACTERIA (MICROORGANISMS); RATTUS; SALMONELLA TYPHIMURIUM; TRICHOPLUSIA NI;

EID: 46649102436     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2008.04.013     Document Type: Article

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