Neonatal 6-hydroxydopamine lesions of the frontal cortex in rats: Persisting effects on locomotor activity, learning and nicotine self-administration

Neuroscience

Volumn 154, Issue 3, 2008, Pages 885-897

  Rezvani, A H ^a   Eddins, D ^a   Slade, S ^a   Hampton, D S ^a   Christopher, N C ^a   Petro, A ^a   Horton, K ^a   Johnson, M ^a   Levin, E D ^a,b  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b DUKE UNIVERSITY   (United States)

Author keywords

5 HT; 6 OHDA; dopamine; nucleus accumbens; radial arm maze; striatum

Indexed keywords

5 HYDROXYINDOLEACETIC ACID; DOPAMINE; NICOTINE; OXIDOPAMINE; SEROTONIN;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN DAMAGE; COGNITION; CONTROLLED STUDY; CORPUS STRIATUM; CORRELATION ANALYSIS; FRONTAL CORTEX; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LEARNING; LOCOMOTION; MAZE TEST; MEMORY; NEWBORN; NONHUMAN; NUCLEUS ACCUMBENS; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; RAT; SEX DIFFERENCE; STATISTICAL SIGNIFICANCE; TASK PERFORMANCE;

ANIMALS; ANIMALS, NEWBORN; BRAIN CHEMISTRY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOPAMINE; FEMALE; LEARNING; MALE; MAZE LEARNING; MEMORY; MOTOR ACTIVITY; NICOTINE; NICOTINIC AGONISTS; NOREPINEPHRINE; OXIDOPAMINE; PREFRONTAL CORTEX; RATS; RATS, SPRAGUE-DAWLEY; SELF ADMINISTRATION; SEROTONIN; SYMPATHECTOMY, CHEMICAL; SYMPATHOLYTICS; TOBACCO USE DISORDER;

EID: 46549086784     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2008.04.020     Document Type: Article

References (58)

1. Archer T., Danysz W., Fredriksson A., Jonsson G., Luthman J., Sundstrom E., and Teiling A. Neonatal 6-hydroxydopamine-induced dopamine depletions: motor activity and performance in maze learning. Pharmacol Biochem Behav 31 (1988) 357-364
2. Avale M.E., Nemirovsky S.I., Raisman-Vozari R., and Rubinstein M. Elevated serotonin is involved in hyperactivity but not in the paradoxical effect of amphetamine in mice neonatally lesioned with 6-hydroxydopamine. J Neurosci Res 78 (2004) 289-296
3. Brocco M., Dekeyne A., Veiga S., Girardon S., and Millan M.J. Induction of hyperlocomotion in mice exposed to a novel environment by inhibition of serotonin reuptake. A pharmacological characterization of diverse classes of antidepressant agents. Pharmacol Biochem Behav 71 (2002) 667-680
4. Chia L.G., Ni D.R., Cheng F.C., Ho Y.P., and Kuo J.S. Intrastriatal injection of 5,7-dihydroxytryptamine decreased 5-HT levels in the striatum and suppressed locomotor activity in C57BL/6 mice. Neurochem Res 24 (1999) 719-722
5. Corrigall W.A. Understanding brain mechanisms in nicotine reinforcement. Br J Addict 86 (1991) 507-510
6. Corrigall W.A. A rodent model for nicotine self-administration. In: Boulton A.A., et al. (Ed). Animal models of drug addiction Vol. 24 (1992), Humana Press Inc, Totowa, NJ 315-344
7. Corrigall W.A., and Coen K.M. Nicotine maintains robust self-administration in rats on a limited-access schedule. Psychopharmacology 99 (1989) 473-478
8. Corrigall W.A., Coen K.M., and Adamson K.L. Self-administered nicotine activates the mesolimbic dopamine system through the ventral tegmental area. Brain Res 653 (1994) 278-284
9. Corrigall W.A., Coen K.M., Adamson K.L., and Chow B.L.C. Response of nicotine self-administration to manipulations of mu-opioid and GABA receptors in the ventral tegmental area. Psychopharmacology 149 (2000) 107-114
10. Descarries L., Soghomonian J.J., Garcia S., Doucet G., and Bruno J.P. Ultrastructural analysis of the serotonin hyperinnervation in adult rat neostriatum following neonatal dopamine denervation with 6-hydroxydopamine. Brain Res 569 (1992) 1-13
11. Deumens R., Blokland A., and Prickaerts J. Modeling Parkinson's disease in rats: an evaluation of 6-OHDA lesions of the nigrostriatal pathway. Exp Neurol 175 (2002) 303-317
12. Di Chiara G. Drug addiction as dopamine-dependent associative learning disorder. Eur J Pharmacol 375 (1999) 13-30
13. Disshon K.A., and Dluzen D.E. Estrogen reduces acute striatal dopamine responses in vivo to the neurotoxin MPP+ in female, but not male rats. Brain Res 868 (2000) 95-104
14. Dluzen D., and Horstink M. Estrogen as neuroprotectant of nigrostriatal dopaminergic system: laboratory and clinical studies. Endocrine 21 (2003) 67-75
15. Dluzen D.E. Effects of testosterone upon MPTP-induced neurotoxicity of the nigrostriatal dopaminergic system of C57/B1 mice. Brain Res 715 (1996) 113-118
16. Dluzen D.E., McDermott J.L., and Liu B. Estrogen alters MPTP-induced neurotoxicity in female mice: effects on striatal dopamine concentrations and release. J Neurochem 66 (1996) 658-666
17. Dluzen D.E., McDermott J.L., and Liu B. Estrogen as a neuroprotectant against MPTP-induced neurotoxicity in C57/B1 mice. Neurotoxicol Teratol 18 (1996) 603-606
18. Donny E.C., Caggiula A.R., Knopf S., and Brown C. Nicotine self-administration in rats. Psychopharmacology 122 (1995) 390-394
19. Donny E.C., Caggiula A.R., Shupenko C.D., Mielke M.M., Booth S., Hoffman A.S., Imerito C.A., Rose C., and McCallum S.E. Nicotine self-administration in male and female rats on fixed and progressive ratio schedules of reinforcement. Soc Neurosci Abstr (1998) 752 294.11
20. Gerfen C.R., Engber T.M., Mahan L.C., Susel Z., Chase T.N., Monsma Jr. F.J., and Sibley D.R. D1 and D2 dopamine receptor-regulated gene expression of striatonigral and striatopallidal neurons. Science 250 (1990) 1429-1432
21. Geyer M.A. Serotonergic functions in arousal and motor activity. Behav Brain Res 73 (1996) 31-35
22. Goldstein R.Z., and Volkow N.D. Drug addiction and its underlying neurobiological basis: neuroimaging evidence for the involvement of the frontal cortex. Am J Psychiatry 159 (2002) 1642-1652
23. Harvey P.D., Rabinowitz J., Eerdekens M., and Davidson M. Treatment of cognitive impairment in early psychosis: a comparison of risperidone and haloperidol in a large long-term trial. Am J Psychiatry 162 (2005) 1888-1895
24. Hughes J. Clinical implications of the association between smoking and alcoholism. In: Fertig J., and Allen J. (Eds). Alcohol and tobacco: From basic science to clinical practice. NIAAA research monograph No. 3 NIH Pub. No. 95-39-31 (1995), US Government Printing Office, Washington, DC 171-185
25. Hughes J.R., Hatsukami D.K., Mitchell J.E., and Dahlgren L.A. Prevalence of smoking among psychiatric outpatients. Am J Psychiatry 143 (1986) 993-997
26. Jacobs B.L., and Fornal C.A. Serotonin and motor activity. Curr Opin Neurobiol 7 (1997) 820-825
27. Kalivas P.W. Neurotransmitter regulation of dopamine neurons in the ventral tegmental area. Brain Res Rev 18 (1993) 75-113
28. Kalivas P.W., and Volkow N.D. The neural basis of addiction: a pathology of motivation and choice. Am J Psychiatry 162 (2005) 1403-1413
29. Koob G.F. Neurobiology of addiction: towards the development of new therapies. Ann N Y Acad Sci 909 (2000) 170-185
30. Krasnova I.N., Betts E.S., Dada A., Jefferson A., Ladenheim B., Becker K.G., Cadet J.L., and Hohmann C.F. Neonatal dopamine depletion induces changes in morphogenesis and gene expression in the developing cortex. Neurotox Res 11 (2007) 107-130
31. Laviolette S., and van der Kooy D. The neurobiology of nicotine addiction: bridging the gap from molecules to behaviour. Nat Rev Neurosci 5 (2004) 55-65
32. Levin E.D., Lawrence S., Petro A., Horton K., Rezvani A.H., Seidler F.J., and Slotkin T.A. Adolescent vs. adult-onset nicotine self-administration in male rats: duration of effect and differential nicotinic receptor correlates. Neurotoxicol Teratol 29 (2007) 458-465
33. Levin E.D., Rezvani A.H., Montoya D., Rose J.E., and Swartzwelder H.S. Adolescent-onset nicotine self-administration modeled in female rats. Psychopharmacology 169 (2003) 141-149
34. Mason G.A., Rezvani A.H., Overstreet D.H., Hamedi M., Walker C.H., Yang Y., and Garbutt J.C. Involvement of dopamine D2 receptors in suppressive effect of the TRH analog TA-0910 on alcohol intake in P rats. Alcohol Clin Exp Res 21 (1997) 1623-1629
35. Miller F.E., Heffner T.G., Kotake C., and Seiden L.S. Magnitude and duration of hyperactivity following neonatal 6-hydroxydopamine is related to the extent of brain dopamine depletion. Brain Res 229 (1981) 123-132
36. Molina-Holgado E., Dewar K.M., Descarries L., and Reader T.A. Altered dopamine and serotonin metabolism in the dopamine-denervated and serotonin-hyperinnervated neostriatum of adult rat after neonatal 6-hydroxydopamine. J Pharmacol Exp Ther 270 (1994) 713-721
37. Morgane P.J., Galler J.R., and Mokler D.J. A review of systems and networks of the limbic forebrain/limbic midbrain. Prog Neurobiol 75 (2005) 143-160
38. Nader M.A., and Czoty P.W. PET imaging of dopamine D2 receptors in monkey models of cocaine abuse: genetic predisposition versus environmental modulation. Am J Psychiatry 162 (2005) 1473-1482
39. Paxinos G., Ashwell K.W.S., and Törk I. Atlas of the developing rat nervous system. Second edition (1994), Academic Press, New York
40. Piazza P.V., Rouge-Pont F., Deminiere J.M., Kharoubi M., Le Moal M., and Simon H. Dopaminergic activity is reduced in the prefrontal cortex and increased in the nucleus accumbens of rats predisposed to develop amphetamine self-administration. Brain Res 567 (1991) 169-174
41. Rex A., and Fink H. Cholecystokinin tetrapeptide improves water maze performance of neonatally 6-hydroxydopamine-lesioned young rats. Pharmacol Biochem Behav 79 (2004) 109-117
42. Rezvani A.H., Garbutt J.C., Shimoda K., Garges P.L., Janowsky D.S., and Mason G.A. Attenuation of alcohol preference in alcohol preferring rats by a novel TRH analogue TA-0910. Alcohol Clin Exp Res 16 (1992) 326-330
43. Rezvani A.H., and Grady D.R. Suppression of alcohol consumption by fenfluramine in fawn-hooded rats with serotonin dysfunction. Pharmacol Biochem Behav 48 (1994) 105-110
44. Rezvani A.H., Overstreet D.H., and Janowsky D.S. Genetic serotonin deficiency and alcohol preference in the fawn hooded rats. Alcohol Alcohol 25 (1990) 573-575
45. Rezvani A.H., Overstreet D.H., Mason G.A., Janowsky D.S., Hamedi M., Clark J.E., and Ying Y. Combination pharmacotherapy: A mixture of small doses of naltrexone, fluoxetine, and a TRH analog reduces alcohol intake in three strains of alcohol preferring rats. Alcohol Alcohol 35 (2000) 76-83
46. Robbins T., and Everitt B. Limbic-striatal memory systems and drug addiction. Neurobiol Learn Mem 78 (2002) 625-636
47. Schilstrom B., Fagerquist M., Zhang X., Hertel P., Panagis G., Nomikos G., and Svensson T. Putative role of presynaptic a7* nicotinic receptors in nicotine stimulated increases of extracellular levels of glutamate and aspartate in the ventral tegmental area. Synapse 38 (2000) 375-383
48. Shaywitz B.A., Yager R.D., and Klopper J.H. Selective brain dopamine depletion in developing rats: an experimental model of minimal brain dysfunction. Science 191 (1976) 305-308
49. Shoaib M., Schindler C.W., and Goldberg S.R. Nicotine self-administration in rats: Strain and nicotine pre-exposure effects on acquisition. Psychopharmacology 129 (1997) 35-43
50. Snedecor G.W., and Cochran W.G. Statistical methods (1967), Iowa State University Press, Ames, IA
51. Snyder A.M., Zigmond M.J., and Lund R.D. Sprouting of serotoninergic afferents into striatum after dopamine-depleting lesions in infant rats: a retrograde transport and immunocytochemical study. J Comp Neurol 245 (1986) 274-281
52. Volkow N.D., Fowler J.S., and Wang G.J. Imaging studies on the role of dopamine in cocaine reinforcement and addiction in humans. J Psychopharmacol 13 (1999) 337-345
53. Volkow N.D., Fowler J.S., Wang G.J., and Goldstein R.Z. Role of dopamine, the frontal cortex and memory circuits in drug addiction: insight from imaging studies. Neurobiol Learn Mem 78 (2002) 610-624
54. Volkow N.D., and Li T.K. Drug addiction: the neurobiology of behaviour gone awry. Nat Rev Neurosci 5 (2004) 963-970
55. Wagner M., Quednow B.B., Westheide J., Schlaepfer T.E., Maier W., and Kuhn K.U. Cognitive improvement in schizophrenic patients does not require a serotonergic mechanism: randomized controlled trial of olanzapine vs amisulpride. Neuropsychopharmacology 30 (2005) 381-390
56. Yoshimoto K., Kaneda S., Kawai Y., Ueda S., Takeuchi Y., Matsushita H., Yuri K., and Yasuhara M. Treating neonatal rats with 6-hydroxydopamine induced an increase in voluntary alcohol consumption. Alcohol Clin Exp Res 23 (1999) 2S-6S
57. Zhang K., Davids E., Tarazi F.I., and Baldessarini R.J. Serotonin transporter binding increases in caudate-putamen and nucleus accumbens after neonatal 6-hydroxydopamine lesions in rats: implications for motor hyperactivity. Brain Res Dev Brain Res 137 (2002) 135-138
58. Zigmond M.J., and Stricker E.M. Recovery of feeding and drinking by rats after intraventricular 6-hydroxydopamine or lateral hypothalamic lesions. Science 182 (1973) 717-720