Biotransformation of cyclosporin in primary rat, porcine and human liver cell co-cultures

Xenobiotica

Volumn 36, Issue 8, 2006, Pages 693-708

  Schmelzer, E ^a   Acikgoez, A ^a   Fruhauf N R ^b   Crome, O ^c   Klempnauer, J ^c   Christians, U ^d   Bader, A ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

^b UNIVERSITY HOSPITAL ESSEN   (Germany)

^c HANNOVER MEDICAL SCHOOL   (Germany)

^d UNIVERSITY OF COLORADO   (United States)

Author keywords

Co culture; Cyclosporin; Immunosuppressive agents; Liver

Indexed keywords

ALBUMIN; CYCLOSPORIN; DRUG METABOLITE; IMMUNOSUPPRESSIVE AGENT;

ADULT; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL METABOLISM; CELL STRUCTURE; CELL TYPE; CELL ULTRASTRUCTURE; COCULTURE; CONTROLLED STUDY; DRUG METABOLISM; DRUG TRANSFORMATION; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL; LIVER METABOLISM; LIVER TOXICITY; NEPHROTOXICITY; NONHUMAN; PROTEIN SYNTHESIS; RAT; SPECIES DIFFERENCE; SWINE;

ANIMALS; BIOTRANSFORMATION; CELLS, CULTURED; COCULTURE TECHNIQUES; CYCLOSPORINE; HEPATOCYTES; HUMANS; INSULIN; MICROSCOPY, ELECTRON, TRANSMISSION; RATS; SERUM ALBUMIN; SWINE; TIME FACTORS;

SUIDAE;

EID: 33746924393     PISSN: 00498254     EISSN: 13665928     Source Type: Journal    
DOI: 10.1080/00498250600674410     Document Type: Article

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