Thermal stabilization of the protozoan Entamoeba histolytica alcohol dehydrogenase by a single proline substitution

Proteins: Structure, Function and Genetics

Volumn 72, Issue 2, 2008, Pages 711-719

  Goihberg, Edi ^a   Dym, Orly ^a   Tel Or, Shoshana ^a   Shimon, Linda ^a   Frolow, Felix ^b   Peretz, Moshe ^a   Burstein, Yigal ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b TEL AVIV UNIVERSITY   (Israel)

Author keywords

Hydrophobic interactions; Intersubunit associations; Protozoan parasite; Site directed mutagenesis; Thermal stability; X ray crystallography

Indexed keywords

ALCOHOL DEHYDROGENASE;

AMINO ACID SUBSTITUTION; ARTICLE; ENTAMOEBA HISTOLYTICA; ENZYME ANALYSIS; ENZYME STABILITY; NONHUMAN; PRIORITY JOURNAL; REVERTANT; SITE DIRECTED MUTAGENESIS; THERMOANAEROBACTER; THERMOANAEROBACTER BROCKII; THERMOSTABILITY;

ALCOHOL DEHYDROGENASE; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CIRCULAR DICHROISM; CRYSTALLOGRAPHY, X-RAY; DNA PRIMERS; ENTAMOEBA HISTOLYTICA; ENZYME STABILITY; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROLINE; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY, AMINO ACID; SPECTROPHOTOMETRY, ULTRAVIOLET;

ENTAMOEBA HISTOLYTICA; PROTOZOA; THERMOANAEROBACTER BROCKII;

EID: 46449123144     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.21946     Document Type: Article

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