Molecular design based on receptor-independent pharmacophore: Application to estrogen receptor ligands

Biological and Pharmaceutical Bulletin

Volumn 31, Issue 7, 2008, Pages 1453-1460

  Islam, Md Ataul ^a   Nagar, Shuchi ^a   Das, Suvadra ^a   Mukherjee, Arup ^a   Saha, Achintya ^a  

^a UNIVERSITY OF CALCUTTA   (India)

Author keywords

Estrogen ligand; Pharmacophore; Receptor binding affinity; Space modeling

Indexed keywords

1,1,2 TRIPHENYLETHYLENE DERIVATIVE; 4 HYDROXYBENZOIC ACID ESTER; ALKANE DERIVATIVE; AROMATIC COMPOUND; BENZOPHENONE DERIVATIVE; CHALCONE DERIVATIVE; CHLORPHENOTANE; DIETHYLSTILBESTROL DERIVATIVE; ESTROGEN DERIVATIVE; ESTROGEN RECEPTOR; FLAVONE DERIVATIVE; HEXESTROL DERIVATIVE; ISOFLAVONE DERIVATIVE; LIGAND; POLYCHLORINATED BIPHENYL DERIVATIVE; SELECTIVE ESTROGEN RECEPTOR MODULATOR; STEROID; STEROID HORMONE; TRANSCRIPTION FACTOR; TRIPHENYLACRYLONITRILE DERIVATIVE;

ARTICLE; CELL NUCLEUS; DIMERIZATION; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; HYDROGEN BOND; HYDROPHOBICITY; MOLECULAR MODEL; PHARMACOPHORE; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RECEPTOR AFFINITY;

DRUG DESIGN; HYDROGEN BONDING; LIGANDS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PROTEIN BINDING; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; RECEPTORS, ESTROGEN;

EID: 46449122832     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.31.1453     Document Type: Article

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