Up-regulation of p21CIP1 expression mediated by ERK-dependent and -independent pathways contributes to hepatocyte growth factor-induced inhibition of HepG2 hepatoma cell proliferation

Journal of Cellular Biochemistry

Volumn 104, Issue 1, 2008, Pages 176-188

  Shirako, Erika ^a   Hirayama, Naoki ^a   Tsukada, Yu Ichi ^a   Tanaka, Toshiaki ^a   Kitamura, Naomi ^a  

^a TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

Author keywords

c Met; Cdk2; EGF receptor; ERK; HepG2; HGF; p16INK4a; p21CIP1

Indexed keywords

CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 2 INHIBITOR; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN DEPENDENT KINASE INHIBITOR 2A; EPIDERMAL GROWTH FACTOR RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; SCATTER FACTOR; SMALL INTERFERING RNA; CDKN1A PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE INHIBITOR 1A;

ARTICLE; CELL CLONING; CELL PROLIFERATION; CELL STRAIN HEPG2; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; HEPATOMA CELL; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; MITOSIS INHIBITION; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION; GENETICS; METABOLISM; PATHOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIN-DEPENDENT KINASE INHIBITOR P21; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HEPATOCYTE GROWTH FACTOR; HUMANS; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 46449107771     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.21614     Document Type: Article

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