Phosphatidylinositol 3-kinase activity is required for hepatocyte growth factor-induced mitogenic signals in epithelial cells

Journal of Biological Chemistry

Volumn 271, Issue 40, 1996, Pages 24850-24855

  Rahimi, Nader ^a,b   Tremblay, Eric ^a   Elliott, Bruce ^a  

^a QUEEN S UNIVERSITY   (Canada)

^b SCHEPENS EYE RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; ENZYME INHIBITOR; GENE PRODUCT; PHOSPHATIDYLINOSITOL 3 KINASE; RECEPTOR; SCATTER FACTOR; TRANSCRIPTION FACTOR; WORTMANNIN;

ANIMAL CELL; ARTICLE; CANCER CELL CULTURE; CELL PROLIFERATION; CONTROLLED STUDY; DNA TRANSFECTION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; EPITHELIUM CELL; GENE EXPRESSION; IMMUNOBLOTTING; IMMUNOPRECIPITATION; MITOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTO ONCOGENE; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; ENZYME ACTIVATION; GENE EXPRESSION; HEPATOCYTE GROWTH FACTOR; MICE; MITOGENS; PHOSPHORYLATION; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-JUN; PROTO-ONCOGENE PROTEINS C-MET; RECEPTOR PROTEIN-TYROSINE KINASES; RIBOSOMAL PROTEIN S6 KINASES; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED; TYROSINE;

ANIMALIA; MURINAE;

EID: 0029760745     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.40.24850     Document Type: Article

References (49)

1. Pepper, M. S., Matsumoto, K., Nakamura, T., Orci, L., and Montesano, R. (1992) J. Biol. Chem. 267, 20493-20496
2. Zarnegar, R., and DeFrances, M. C. (1993) Exper. Suppl. (Basel) 65, 181-199
3. DeFrances, M. C., Wolf, H. K., Michalopoulos, G. K., and Zarnegar, R. (1992) Development 116, 387-395
4. Noji, S., Tashiro, K., Koyama, E., Nohno, T., Ohyama, K., Taniguchi, S., and Nakamura, T. (1990) Biochem. Biophys. Res. Commun. 173, 42-47
5. Matsumoto, K., and Nakamura, T. (1993) Exper. Suppl. (Basel) 65, 225-249
6. Santos, O. F., Moura, L. A., Rosen, E. M., and Nigam, S. K. (1993) Dev. Biol. 159, 535-548
7. Rosen, E. M., Grant, D. S., Kleinman, H. K., Goldberg, I. D., Bhargava, M. M., Nickoloff, B. J., Kinsella, J. L., and Polverini, P. (1993) Symposia Soc. Exp. Biol. 47, 227-234
8. Rahimi, N., Saulnier, R., Nakamura, T., Park, M., and Elliott, B. (1994) DNA Cell Biol. 13, 1189-1197
9. Bottaro, D. P., Rubin, J. S., Faletto, D. L., Chan, A. M., Kmiecik, T. E., Vande Woude, G. F., and Aaronson, S. A. (1991) Science 251, 802-804
10. Lehtola, L., Sistonen, L., Koskinen, P., Lehvaslaiho, H., Di Renzo, M. F., Comoglio, P. M., and Alitalo, K. (1991) J. Cell. Biochem. 45, 69-81
11. Naldini, L., Vigna, E., Narsimhan, R. P., Gaudino, G., Zarnegar, R., Michalopoulos, G. K., and Comoglio, P. M. (1991) Oncogene 6, 501-504
12. Ferracini, R., Longati, P., Naldini, L., Vigna, E., and Comoglio, P. M. (1991) J. Biol. Chem. 266, 19558-19564
13. Longati, P., Bardelli, A., Ponzetto, C., Naldini, L., and Comoglio, P. M. (1994) Oncogene 9, 49-57
14. Zhen, Z., Giordano, S., Longati, P., Medico, E., Campiglio, M., and Comoglio, P. M. (1994) Oncogens 9, 1691-1697
15. Ponzetto, C., Bardelli, A., Maina, F., Longati, P., Panayotou, G., Dhand, R., Waterfield, M. D., and Comoglio, P. M. (1993) Mol. Cell. Biol. 13, 4600-4608
16. Ponzetto, C., Bardelli, A., Zhen, Z., Maina, F., dalla Zonca, P., Giordano, S. A. U., Panayotou, G., and Comoglio, P. M. (1994) Cell 77, 261-271
17. Graziani, A., Gramaglia, D., dalla Zonca, P., and Comoglio, P. M. (1993) J. Biol. Chem. 268, 9165-9168
18. Fixman, E. D., Naujokas, M. A., Rodrigues, G. A., Moran, M. F., and Park, M. (1995) Oncogene 10, 237-249
19. Auger, K. R., Serunian, L. A., Soltoff, S. P., Libby, P., and Cantley, L. C. (1989) Cell 57, 167-175
20. Carpenter, C. L., Duckworth, B. C., Auger, K. R., Cohen, B., Schaffhausen, B. S., and Cantley, L. C. (1990) J. Biol. Chem. 265, 19704-19711
21. Whitman, M., Downes, C. P., Keeler, M., Keller, T., and Cantley, L. (1988) Nature 332, 644-646
22. Chung, J., Grammer, T. C., Lemon, K. P., Kazlauskas, A., and Blenis, J. (1994) Nature 370, 71-75
23. Nakanishi, H., Brewer, K. A., and Exton, J. H. (1993) J. Biol. Chem. 268, 13-16
24. Wymann, M., and Arcaro, A. (1994) Biochem. J. 298, 517-520
25. Zhang, J., Fry, M. J., Waterfield, M. D., Jaken, S., Liao, L., Fox, J. E. B., and Rittenhouse, S. E. (1992) J. Biol. Chem. 267, 4686-4692
26. Sjolander, A., Yamamoto, K., Huber, B. E., and Lapetina, E. G. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 7908-7912
27. Hu, Q., Klippel, A., Muslin, A. J., Fantl, W. J., and Williams, L. T. (1995) Science 268, 100-102
28. Fantl, W. J., Escobedo, J. A., Martin, G. A., Turck, C. W., del Rosario, M., McCormick, F., and Williams, L. T. (1992) Cell 69, 413-423
29. Yang, M. X., and Park, M. (1993) Dev. Biol. 157, 308-320
30. Hara, K., Yonezawa, K., Sakaue, H., Ando, A., Kotani, K., Kitamura, T., Kitamura, Y., Ueda, H., Stephens, L., Jackson, T. R., Hawkins, P. T., Dhand, R., Clark, A. E., Holman, G. D., Waterfield, M. D., and Kasnga, M. (1992) Proc. Natl. Acad. Sci. U. S. A. 91, 7415-7419
31. Carlow, D. A., Kerbel, R. S., Feltis, J. T., and Elliott, B. (1989) J. Natl. Cancer Inst. 75, 291-301
32. Rahimi, N., Tremblay, E., Mc Adam, L., Park, M., Schwall, R., and Elliott, B. (1996) Cell Growth & Differ. 7, 263-270
33. Friedrich, G., and Soriano, P. (1991) Genes & Dev. 5, 1513-1523
34. Yao, R., and Cooper, G. M. (1995) Science 267, 2003-2006
35. Whitman, M., Kaplan, D. R., Schaffhausen, B., Cantley, L., and Roberts, T. M. (1985) Nature 315, 239-242
36. Yano, H., Nakanishi, S., Kimura, K., Hanai, N., Saitoh, Y., Fukui, Y., Nonomura, Y., and Matsuda, Y. (1993) J. Biol. Chem. 268, 25846-25856
37. Lu, Y., Phillips, C. A., and Trevillyan, J. M. (1995) Eur. J. Immunol. 25, 533-537
38. Powis, G., Bonjouklian, R., Berggren, M. M., Gallegos, A., Abraham, R., Ashendel, C., Zalkow, L., Matter, W. F., Dodge, J., Grindey, G., and Vlahos, C. J. (1994) Cancer Res. 54, 2419-2423
39. Petrisch, C., Woscholski, R., Edelmann, H. L., Parker, P., Ballou, L. M. (1995) Eur. J. Biochem. 230, 431-438
40. Chung, J., Kuo, C. J., Crabtree, G. R., and Blenis, J. (1992) Cell 78, 35-43
41. Angel, P., and Karin, M. (1991) Biochim. Biophys. Acta 1072, 129-157
42. Hartmann, G., Weidner, K. M., Schwarz, H., and Birchmeier, W. (1994) J. Biol. Chem. 269, 21936-21939
43. Gandino, L., Di Renzo, M. F., Giordano, S., Bussolino, F., and Comoglio, P. M. (1990) Oncogene 5, 721-725
44. Lane, H. A., Fernandez, A., Lamb, N. J., and Thomas, G. (1993) Nature 363, 170-173
45. Kikkawa, U., Takai, Y., Tanaka, Y., Miyake, R., and Nishizuka, Y. (1983) J. Biol. Chem. 258, 11442-11445
46. Angel, P., Imagawa, M., Chiu, R., Stein, B., Imbra, R. J., Rahmsdorf, H. J., Jonat, C., Herrlich, P., and Karin, M. (1987) Cell 49, 729-739
47. Brenner, D. A., O'Hara, M., Angel, P., Chojkier, M., and Karin, M. (1989) Nature 337, 661-663
48. Gandino, L., Di Renzo, M. F., Giordano, S., Bussolino, F., and Comoglio, P. M. (1990) Oncogene 5, 721-725
49. Royal, I., and Park, M. (1995) J. Biol. Chem. 270, 27780-27787