Potential genotoxicity from integration sites in CLAD dogs treated successfully with gammaretroviral vector-mediated gene therapy

Gene Therapy

Volumn 15, Issue 14, 2008, Pages 1067-1071

  Hai, M ^a   Adler, R L ^a   Bauer, T R ^a   Tuschong, L M ^a   Gu, Y C ^a   Wu, X ^b   Hickstein, D D ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b SAIC FREDERICK INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD18 ANTIGEN; CD3 ANTIGEN; RETROVIRUS VECTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOTRANSPLANTATION; CANINE LEUKOCYTE ADHESION DEFICIENCY; CONTROLLED STUDY; DOG; GENE INSERTION; GENOTOXICITY; HEMATOPOIETIC STEM CELL TRANSPLANTATION; LEUKOCYTE; LEUKOCYTE ADHESION DEFICIENCY; NEUTROPHIL; NONHUMAN; ONCOGENE; PRIORITY JOURNAL; STEM CELL GENE THERAPY; T LYMPHOCYTE; TRANSCRIPTION INITIATION; VIRAL GENE DELIVERY SYSTEM;

ANIMALS; ANTIGENS, CD18; DOG DISEASES; DOGS; GAMMARETROVIRUS; GENE THERAPY; GENETIC VECTORS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATOPOIETIC STEM CELLS; LEUKOCYTE-ADHESION DEFICIENCY SYNDROME; MUTAGENESIS, INSERTIONAL; NEUTROPHILS; T-LYMPHOCYTES; TIME; TRANSCRIPTION, GENETIC; VIRUS INTEGRATION;

ANIMALIA; CANIS FAMILIARIS;

EID: 46449093476     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/gt.2008.52     Document Type: Article

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