Microdosimetric assessment of nice therapeutic proton beam biological quality

Physica Medica

Volumn 20, Issue 2, 2004, Pages 71-77

  De Nardo, Laura ^a,b   Cesari, Valentina ^c   Iborra, Nicole ^d   Conte, Valeria ^c   Colautti, Paolo ^c   Héraul, Joël ^d   Tornielli, Giorgio ^b   Chauvel, Pierre ^d  

^a UNIVERSITY OF PADOVA   (Italy)

^b SEZIONE DI PADOVA   (Italy)

^c LABORATORI NAZIONALI DI LEGNARO   (Italy)

^d CENTRE ANTOINE LACASSAGNE   (France)

Author keywords

Microdosimetry; Proton RBE; Proton therapy; TEPC

Indexed keywords

ANIMAL CELL; ARTICLE; CYCLOTRON; DOSIMETRY; HUMAN; INTESTINE CRYPT; INTESTINE EPITHELIUM CELL; IRRADIATION; MEASUREMENT; MELANOMA; MICRODOSIMETRY; MOUSE; NONHUMAN; PHANTOM; PROTON RADIATION; RADIATION DOSE; RELATIVE BIOLOGIC EFFECTIVENESS; SQUAMOUS CELL CARCINOMA; TISSUE EQUIVALENT PROPORTIONAL COUNTER; TONGUE CARCINOMA;

ANIMALIA;

EID: 4644371812     PISSN: 11201797     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Coutrakon G, Cortese J, Ghebremedhin A, Hubbard J, Johanning J, Koss P, Maudsley G, Slater C R, Zuccarelli C. Microdosimetry spectra of the Loma Linda proton beam and relative biological effectiveness comparison. Medical Physics 1997: 24; 1499-1506.
2. Loncol T, Cosgrove V, Denis J M, Gueulette J, Mazal A, Menzel H G, Pihet P, Sabattier R. Radiobiological effectiveness of radiation beams with broad LET spectra: microdosimetric analysis using biological weighting functions. Radiat Prot Dosim 1994: 52; 347-352.
3. Cosgrove V P, Delacroix S, Green S, Mazal A, Scott M C. Microdosimetric studies on the Orsay proton synchrocyclotron at 73 and 200 MeV. Radiat Prot Dosim 1997: 70; 493-496.
4. Cesari V, Iborra N, De Nardo L, Querini P, Conte V, Colautti P, Tornielli G, Chauvel P. Microdosimetric measurements of the Nice therapeutic proton beam. Physica Medica 2001: XVII (Suppl 3); 76-82.
5. Bond V P, Varma M N. A stochastic, weighted hit size theory of cellular radiobiological action. In: Proc 8th Microdos Symp. Jülich 1982. Booz, Eberts Eds. CEC Report EUR 8395: 1983; 423-437.
6. Chauvel P et alii. Status report on the installation of proton and neutron therapy in Centre Antoine-Lacassagne. In Proceedings of the EPAC 90 1990: vol. 2; S85-S87.
7. th int. conference of cyclotrons and their applications, Berlin, May 8-12 1989; 156-159.
8. Braby L A, Johnson G W, Barthe J. Practical considerations in the design and construction of tissue-equivalent proportional counters. Radiat Prot Dosim 1995: 61; 351-379.
9. De Nardo L, Cesari V, Dona G, Magrin G, Colautti P, Conte V, Tornielli G. Mini TEPCS for radiation therapy. Radiat Prot Dosim 2004: 108; 345-352.
10. Microdosimetry. ICRU 1983. Report 36.
11. Kellerer A M. Future aims of biophysical models. In: Biophysical modelling of radiation effects. Chadwick, Moschini, Varma Eds. Adam Hilger 1992; 309-314.
12. Tilikidis A, Lindt B, Näfstadius P, Brahme A. An estimation of relative biological effectiveness of 50 MV bremsstrahlung beams by microdosimetric techniques. Phys Med Biol 1996: 41; 55-69.
13. Pihet P. Etude microdosimétrique de faisceaux de neutrons de haute énergie. Application dosimétrique et radiobiologiques. Thesis. Louvain-La-Neuve. Universitè Catholique de Louvain 1989.
14. Pihet P, Menzel H G, Schmidt R, Beauduin M, Wambersite A. Biological weighting function for RBE specification of neutron therapy Seams. Intercomparison of 9 European centres. Radiat Prot Dosim 1990: 31; 437-442.
15. Moro D, Seravalli E, Colautti P. Statistical and overall uncertainties in proton therapy microdosimetric measurements. LNL-INFN 2003: Report LNL-INFN(REP) 200/2003.
16. Vynckier S, Bonnet D E, Jones D T L. The code of practice for proton dosimetry. Radiotherapy and Oncology 1991: 20; 53-63.
17. Vynckier S, Bonnet D E, Jones D T L. Supplement to the code of practice for proton dosimetry. Radiotherapy and Oncology 1994; 32; 174-179.
18. Stopping powers and ranges for protons and alpha partides. ICRU 1993: Report 49.
19. Robertson JB, Eaddy J M, Archambeau J O, Coutrakon G B, Miller D W, Moyers M F, Siebers J V, Slater J M, Dicello J F. Variation of measured proton relative biological effectiveness as a function of initial proton energy. In: Hadrontherapy in Oncology, Amaldi U, Larsson B Eds. Amsterdam. Excerpta Medica 1994; 706-711.
20. Paganetti H. Nuclear interactions in proton therapy: dose and relative biological effect distributions originating from primary and secondary particles. Phys Med Biol 2002: 47; 747-764.
21. Biaggi M, Ballarini F, Burkhard W, Egger E, Ferrari A, Ottolenghi A. Physical and biophysical characteristics of a fully modulated 72 MeV therapeutic proton beam: model prediction and experimental data. NIM B 1999: 159; 89-100.
22. Bettega D, Birattari C, Bombana M, Fuhrman Conti A M, Gallini E, Pelucchi T, Tallone Lombardi L. Relative biological effectiveness for protons of energy up to 31 MeV. Radiation Research 1979: 77; 85-97.
23. Belli M, Cherubini R, Finotto S, Moschini G, Sapora O, Simone G, Tabocchini M A. RBE-LET relationship for the survival of V79 cell irradiated with low energy protons. Int J Rad Biol 1989: 55; 93-104.
24. Paganetti H, Niemierko A, Ancukiewicz M, Gerweck L E, Goitein M, Loeffler J S, Suit H D. Relative biological effectiveness (RBE) values for proton beam therapy. Int J Rad Onc Biol Phys 2002: 53; 407-421.
25. Verhaegen F, Palmas H. Microdosimetric characterisation of clinical proton beams. In: Microdosimetry. An interdisciplinary approach, Goodhead D T, O'Neill P, Menzel H G Eds. Royal Society of Chemistry (UK) 1997: publication 204; 270-273.
26. Courdi A, Brassart N, Herault J, Chauvel P. The depth-dependent radiation response of human melanoma cells to 65 MeV protons. British J Rad 1994: 67; 800-804.
27. Bettega D, Calzolari P, Chauvel P, Courdi A, Herault J, Iborra N, Marchesini R, Massariello P, Poli G L, Tallone L. Radiobiological studies of the 65 MeV therapeutic proton beam at Nice using human tumour cells. Int J Rad Biol 2000: 76; 1297-1303.
28. Matsubara S, Ohara H, Hiraoka T, Koike S, Ando K, Yamaguchi H, Kuwabara Y, Hoshina M, Suzuki S. Chromosome aberration frequencies produced by a 70 MeV proton beam. Radiation Research 1990: 123; 182-191.
29. Paganetti H, Olko P, Kobus H, Becker R, Schmitz T, Waligorski M P R, Filges D, Müller-Gärtner A W. Calculations of relative biological effectiveness for proton beams using biological weighting functions. Int J Rad Onc Biol Phys 1997: 37; 719-729.
30. Paganetti H. Calculation of spatial variation of relative biological effectiveness in a therapeutic proton field for H eye treatment. Phys Med Biol 1998: 43; 2147-2157.
31. Andreo P, Brahme A. Mean energy in electron beams. Med Phys 1981: 8; 682-687.