Calculation of the spatial variation of relative biological effectiveness in a therapeutic proton field for eye treatment

Physics in Medicine and Biology

Volumn 43, Issue 8, 1998, Pages 2147-2157

  Paganetti, H ^a  

^a HAHN MEITNER INSTITUT   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

COBALT 60;

ANIMAL CELL; ARTICLE; BEAM THERAPY; COLLIMATOR; DOSE CALCULATION; EYE TUMOR; GAMMA IRRADIATION; MODEL; NONHUMAN; PRIORITY JOURNAL; PROTON RADIATION; RADIATION DOSE; THREE DIMENSIONAL IMAGING; TREATMENT PLANNING;

ANIMALS; CELL LINE; CELL SURVIVAL; CRICETINAE; EQUIPMENT DESIGN; EYE NEOPLASMS; HUMANS; MONTE CARLO METHOD; PHANTOMS, IMAGING; PROTONS; RADIOTHERAPY; RADIOTHERAPY PLANNING, COMPUTER-ASSISTED; SCATTERING, RADIATION; WATER;

EID: 0031829098     PISSN: 00319155     EISSN: None     Source Type: Journal    
DOI: 10.1088/0031-9155/43/8/011     Document Type: Article

References (26)

1. Alsmiller R G, Santoro R T, Armstrong T W, Barish J, Chandler K C and Chapman G T 1974 Calculations related to the possible use of photons, neutrons, negative charged pions, protons, and alpha particles in radiotherapy Radiat. Res. 60 369-87
2. Belli M, Cherubini R, Finotto S, Moschini G, Sapora O, Simone G and Tabocchini M A 1989 RBE-LET relationship for the survival of V79 cells irradiated with low energy protons Int. J. Radiat. Biol. 55 93-104
3. Bird R P, Rohrig N, Colvett R D, Geard C R and Marino S A 1980 Inactivation of synchronized Chinese hamster V79 cells with charged-particle track segments Radiat. Res. 82 277-89
4. 60Co gamma-radiation using two cell lines Radiother. Oncol. 28 44-51
5. Butts J J and Katz R 1967 Theory of RBE for heavy ion bombardment of dry enzymes and viruses Radial Res. 30 855-71
6. Courdi A, Brassart N, Herault J and Chauvel P 1994 The depth-dependent radiation response of human melanoma cells exposed to 65 MeV protons Br. J. Radiol 67 800-4
7. GEANT 1994 Detector Description and Simulation Toot Version 3.21 CERN Program Library
8. Gueulette J, Gregoire V, Octave-Prignot M and Wambersie A 1996 Measurements of radiobiological effectiveness in the 85 MeV proton beam produced at the cyclotron CYCLONE of Louvain-la-Neuve, Belgium Radiat. Res. 145 70-1
9. Hall E J, Kellerer A M, Rossi H H, and Yuk-Ming P L 1978 The relative biological effectiveness of 160 MeV protons. II. Biological data and their interpretation in terms of microdosimetry Int. J. Radiat. Oncol. Biol. Phys. 4 1009-13
10. Heese J, Gehrmann S, Homeyer H, Kluge H and Morgenstern H 1994 Determination of the proton energy distribution at the 72-MeV Cyclotron VICKSI at HMI-Berlin XXI PTCOG meeting (Chiba, Japan)
11. Hofmann W and Daschil F 1985 Biological effects of alpha particles in lung tissue Radial. Protect. Dosim. 13 229-32
12. Katz R and Sharma S C 1973 Response of cells to fast neutrons, stopped pions, and heavy ion beams Nucl. Instrum. Methods 111 93-116
13. _ 1974 Heavy particles in therapy: An application of track theory Phys. Med. Biol. 19 413-35
14. Katz R, Zachariah R, Cucinotta F A and Zhang C 1994 Survey of cellular radiosensitivity parameters Radiat. Res. 140 356-65
15. Paganetti H 1998 Monte Carlo method to study the proton fiuence for treatment planning Med. Phys. submitted
16. Paganetti H, Olko P, Kobus H, Becker R, Schmilz Th, Waligorski M P R, Filges D, and Mueller-Gaertner H W 1997 Calculation of RBE for proton beams using biological weighting functions Int. J. Radiat. Oncol. Biol. Phys. 37 719-29
17. Paganetti H and Schmilz Th 1996 The influence of the beam modulation method on dose and RBE in proton radiation therapy Phys. Med. Biol. 41 1649-63
18. Perris A, Pialoglou P, Katsanos A A and Sideris E G 1986 Biological effectiveness of low energy protons. I. Survival of Chinese hamster cells Int. J. Radiat. Biol. 50 1093-101
19. Robertson J B, Eaddy J M, Archambeau J O, Coutrakon G B, Miller D W, Moyers M F, Siebers J V, Slater J M and Dicello J F 1994 Variation of measured proton relative biological effectiveness (RBE) as a function of initial proton energy Hadrontherapy and Oncology ed U Amaldi and B Larsson (Amsterdam: Excerpta Medica) pp 706-11
20. Robertson J B, Williams J R, Schmidt R A, Little J B, Flynn D F and Suit H D 1975 Radiobiological studies of a high-energy modulated proton beam utilizing cultured mammalian cells Cancer 35 1664-77
21. Roth R A, Sharma S C and Katz R 1976 Systematic evaluation of cellular radiosensitivity parameters Phys. Med. Biol. 21 491-503
22. Tepper J, Verhey L, Goitein M and Suit H D 1977 In vivo determinations of RBE in a high energy modulated proton beam using normal tissue reactions and fractionated dose schedules Int. J. Radiat. Oncol. Biol. Phys. 2 1115-22
23. Urano M, Goitein M, Verhey L, Mendiondo O, Suit H D and Koehler A 1980 Relative biological effectiveness of a high energy modulated proton beam using a spontaneous murine tumor in vivo Int. J. Radiat. Oncol. Biol. Phys. 6 1187-93
24. Urano M, Verhey L J, Goitein M, Tepper J E, Suit H D, Mendiondo O, Gragoudas E S and Koehler A 1984 Relative biological effectiveness of modulated proton beams in various murine tissues Int. J. Radiat. Oncol. Biol Phys. 10 509-14
25. Wainson A A, Lomanov M F, Shmakova N L, Blokhin S I and Jarmonenko S P 1972 The RBE of accelerated protons in different parts of the Bragg curve Br. J. Radial. 45 525-9
26. Wouters B G, Lam G K Y, Oelfke U, Gardey K, Durand R E and Skarsgard L D 1996 RBE measurement on the 70 MeV proton beam at TRIUMF using V79 cells and the high precision cell sorter assay Radiat. Res. 146 159-70