Interaction of nucleoside analogues with nucleoside transporters in rat brain endothelial cells

Journal of Drug Targeting

Volumn 12, Issue 5, 2004, Pages 265-272

  Chishty, Mansoor ^a,b   Begley, David J ^a   Abbott, N Joan ^a   Reichel, Andreas ^a,c  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b Pharmidex   (United Kingdom)

^c BAYER PHARMA AG   (Germany)

Author keywords

Adenosine; Anti viral; Blood brain barrier; Nucleoside transporters; RBE4; Structure activity relationship

Indexed keywords

ADENOSINE A1 RECEPTOR AGONIST; ANTIVIRUS AGENT; CCL 4019; DRUG CARRIER; GR 150185; GR 242468; GR 395849; GR 56071X; GR 56072X; GR 66683X; GR 79236X; GW 274666X; LAMIVUDINE; NUCLEOSIDE ANALOG; NUCLEOSIDE TRANSPORTER; PRODRUG; RIBOSE; STAVUDINE; UNCLASSIFIED DRUG; ZIDOVUDINE;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING SITE; BLOOD BRAIN BARRIER; BRAIN CELL; CELL LINE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG PENETRATION; DRUG STRUCTURE; DRUG TRANSPORT; ENDOTHELIUM CELL; EXPERIMENTAL MODEL; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IN VITRO STUDY; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; RAT; STRUCTURAL HOMOLOGY; STRUCTURE ACTIVITY RELATION;

ADENOSINE; ANIMALS; ANTIVIRAL AGENTS; BIOLOGICAL TRANSPORT; BLOOD-BRAIN BARRIER; BRAIN; CELLS, CULTURED; ENDOTHELIAL CELLS; NUCLEOSIDE TRANSPORT PROTEINS; NUCLEOSIDES; RATS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 4644360379     PISSN: 1061186X     EISSN: None     Source Type: Journal    
DOI: 10.1080/10611860410001731398     Document Type: Article

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