Effect of transport inhibitors and additional anti-HIV drugs on the movement of lamivudine (3TC) across the guinea pig brain barriers

Journal of Pharmacology and Experimental Therapeutics

Volumn 306, Issue 3, 2003, Pages 1035-1041

  Gibbs, J E ^a   Rashid, T ^a   Thomas, Sarah A ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2,4 DICHLOROPHENOXYACETIC ACID; 4 AMINOHIPPURIC ACID; ABACAVIR; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; CARRIER PROTEIN; DIDANOSINE; DIGOXIN; INDOMETACIN; LAMIVUDINE; NUCLEOSIDE ANALOG; PROBENECID; PROGESTERONE; STAVUDINE; TRICARBOXYLIC ACID; TRIETHANOLAMINE; TRIMETHOPRIM; ZIDOVUDINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING COMPETITION; BLOOD BRAIN BARRIER; BLOOD CEREBROSPINAL FLUID BARRIER; BRAIN PERFUSION; CENTRAL NERVOUS SYSTEM; CHOROID PLEXUS; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG BRAIN LEVEL; DRUG PROTEIN BINDING; DRUG TRANSPORT; DRUG UPTAKE; GUINEA PIG; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTI-HIV AGENTS; BIOLOGICAL TRANSPORT; BLOOD-BRAIN BARRIER; BRAIN; CHOROID PLEXUS; GUINEA PIGS; LAMIVUDINE; OCTANOLS; PROTEIN BINDING; TIME FACTORS;

EID: 0042934026     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.103.053827     Document Type: Article

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