Regioselective synthesis of fluoroalkylated [1,2,3]-triazoles by Huisgen cycloaddition

Journal of Fluorine Chemistry

Volumn 125, Issue 10, 2004, Pages 1415-1423

  Wu, Yong Ming ^a   Deng, Juan ^a   Fang, Xiang ^a   Chen, Qing Yun ^a  

^a SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY   (China)

Author keywords

1,3 Dipolar cycloaddition; 1,4 Disubstituted 1,2,3 triazole; Fluoroalkylazide; Internal alkyne; Propiolic ester(amide); Regioselective

Indexed keywords

1 (2,2,2 TRIFLUOROETHYL) 4 ACETYLOXYMETHYL 1H[1,2,3]TRIAZOLE; 1 (2,2,3,3 TETRAFLUOROPROPYL) 4 (TETRAHYDROPYRAN 2 YLOXYMETHYL) 1H[1,2,3]TRIAZOLE; 1 (2,2,3,3 TETRAFLUOROPROPYL) 4 ACETYLOXYMETHYL 1H[1,2,3]TRIAZOLE; 1 (2,2,3,3,4,4,5,5,6,6,7,7,7 TRIDECAFLUOROHEPTYL) 4 ACETYLOXYMETHYL 1H[1,2,3]TRIAZOLE; 1,2,3 TRIAZOLE DERIVATIVE; 2 PROPYNYL 1 (2,2,2 TRIFLUOROETHYL) 1H[1,2,3]TRIAZOLE 4 CARBOXYLIC ACID ESTER; 2 PROPYNYL 1 (2,2,3,3 TETRAFLUOROPROPYL) 1H[1,2,3]TRIAZOLE 4 CARBOXYLIC ACID ESTER; 2 PROPYNYL 1 (2,2,3,3,4,4,5,5,6,6,7,7,7 TRIDECAFLUOROHEPTYL) 1H[1,2,3]TRIAZOLE 4 CARBOXYLIC ACID ESTER; 4 (TETRAHYDROPYRAN 2 YLOXYMETHYL) 1 (2,2,2 TRIFLUOROETHYL) 1H[1,2,3]TRIAZOLE; 4 (TETRAHYDROPYRAN 2 YLOXYMETHYL) 1 (2,2,3,3,4,4,5,5,6,6,7,7,7 TRIDECAFLUOROHEPTYL) 1H[1,2,3]TRIAZOLE; 4 BUTYL 1 (2,2,2 TRIFLUOROETHYL) 1H[1,2,3]TRIAZOLE; 4 BUTYL 1 (2,2,3,3 TETRAFLUOROPROPYL) 1H[1,2,3]TRIAZOLE; 4 BUTYL 1 (2,2,3,3,4,4,5,5,6,6,7,7,7 TRIDECAFLUOROHEPTYL) 1H[1,2,3]TRIAZOLE; 4 HEXYL 1 (2,2,2 TRIFLUOROETHYL) 1H[1,2,3]TRIAZOLE; 4 HEXYL 1 (2,2,3,3 TETRAFLUOROPROPYL) 1H[1,2,3]TRIAZOLE; 4 HEXYL 1 (2,2,3,3,4,4,5,5,6,6,7,7,7 TRIDECAFLUOROHEPTYL) 1H[1,2,3]TRIAZOLE; 4 PHENYL 1 (2,2,2 TRIFLUOROETHYL) 1H[1,2,3]TRIAZOLE; 4 PHENYL 1 (2,2,3,3 TETRAFLUOROPROPYL) 1H[1,2,3]TRIAZOLE; 4 PHENYL 1 (2,2,3,3,4,4,5,5,6,6,7,7,7 TRIDECAFLUOROHEPTYL) 1H[1,2,3]TRIAZOLE; ALKYNE; AMIDE; AZIDE; COPPER; FLUORINE DERIVATIVE; LIGAND; METHYL 1 (2,2,2 TRIFLUOROETHYL) 1H[1,2,3]TRIAZOLE 4 CARBOXYLIC ACID ESTER; METHYL 1 (2,2,3,3 TETRAFLUOROPROPYL) 1H[1,2,3]TRIAZOLE 4 CARBOXYLIC ACID ESTER; METHYL 1 (2,2,3,3,4,4,5,5,6,6,7,7,7 TRIDECAFLUOROHEPTYL) 1H[1,2,3]TRIAZOLE 4 CARBOXYLIC ACID ESTER; TRIETHYLAMINE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ARTICLE; CATALYST; CHEMICAL REACTION; CYCLOADDITION; DRUG STRUCTURE; DRUG SYNTHESIS; ROOM TEMPERATURE;

EID: 4644326987     PISSN: 00221139     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jfluchem.2004.02.016     Document Type: Article

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