Effects of bepotastine, cetirizine, fexofenadine, and olopatadine on histamine-induced wheal-and flare-response, sedation, and psychomotor performance

Clinical and Experimental Dermatology

Volumn 29, Issue 5, 2004, Pages 526-532

  Takahashi, H ^a   Ishida Yamamoto, A ^a   Iizuka, H ^a  

^a ASAHIKAWA MEDICAL COLLEGE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIHISTAMINIC AGENT; BETOTASTINE; CETIRIZINE; FEXOFENADINE; HISTAMINE; OLOPATADINE; PLACEBO;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DISEASE EXACERBATION; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DROWSINESS; DRUG EFFECT; FEMALE; HUMAN; HUMAN EXPERIMENT; IONTOPHORESIS; MALE; NORMAL HUMAN; PRIORITY JOURNAL; PSYCHOMOTOR DISORDER; PSYCHOMOTOR PERFORMANCE; RANDOMIZED CONTROLLED TRIAL; SEDATION; SIDE EFFECT; URTICARIA; VISUAL ANALOG SCALE;

ADULT; CETIRIZINE; CROSS-OVER STUDIES; DERMATITIS, ATOPIC; DIBENZOXEPINS; DOUBLE-BLIND METHOD; FEMALE; HISTAMINE; HISTAMINE H1 ANTAGONISTS; HUMANS; IONTOPHORESIS; MALE; PIPERIDINES; PSYCHOMOTOR PERFORMANCE; PYRIDINES; SLEEP STAGES; TERFENADINE;

EID: 4644302246     PISSN: 03076938     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2230.2004.01618.x     Document Type: Article

References (26)

1. 1-Receptor Antagonists in Allergic Diseases. New York: Marcel Dekker; 1996: 273-96.
2. 1- receptor-antagonist drugs. N. Engl J Med 1994; 330: 1663-70.
3. Passalacqua G, Canonica GW, Bousquet J. Structure and classification of H1-antihistamines and overview of their activities. Clin Allergy Immunol 2002; 17: 65-100.
4. 1-receptor antagonists. An EAACI position paper. Allergy 1996; 51: 666-75.
5. Welch MJ, Metzer EO, Simons FE. H1-antihistamines and the central nervous system. Clin Allergy Immunol 2002; 17: 337-88.
6. Juhlin L, de Vos C, Rihoux JP. Inhibiting effect of cetirizine on histamine-induced and 48/80-induced wheals and flares, experimental dermographism, and cold-induced urticaria. J Allergy Clin Immunol 1987; 80: 599-602.
7. Ueno M, Inagaki N, Nagai H et al. Antiallergic action of bepotastine besilate (TAU-284) in animal models: a comparison with ketotifen. Pharmacology 1998; 57: 206-14.
8. Kawashima M, Harada S, Tango T. Review of fexofenadine in the treatment of chronic idiopathic urticaria. Int J Dermatol 2002; 41: 701-6.
9. Ohmori K, Ishii H, Sasaki Y et al. Effects of KW-4679, a new orally active antiallergic drug, on antigen-induced bronchial hyperresponsiveness, airway inflammation and immediate and late asthmatic responses in guinea pigs. Int Arch Allergy Immunol 1996; 110: 64-72.
10. Morita K, Koga T, Moroi Y et al. Rapid effects of olopatadine hydrochloride on the histamine-induced skin responses. J Dermatol 2002; 29: 709-12.
11. Ohmori K, Hayashi K, Kasei T et al. Pharmacological, pharmacokinetics and clinical properties of olopatadine hydrochloride, a new antiallergic drug. Jpn J Pharmacol 2002; 88: 379-97.
12. Mattila MI, Paakkari I. Variations among non-sedating antihistamines: are there real differences? Eur J Clin Pharmacol 1999; 55: 85-93.
13. Furue M, Terao H, Koga T. Effects of cetirizine and epinastine on the skin response to histamine iontophoresis. J Dermatol Sci 2001; 25: 59-63.
14. Urae A, Okada M, Irie S et al. Effects of fexofenadine hydrochloride on psychomotor performance: Comparison of impaired performance of a word processor by fexofenadine hydrochloride with that by d-chlorpheniramine maleate in healthy volunteers (in Japanese; abstract in English). Jpn J Clin Pharmacol Ther 2000; 31: 649-58.
15. Hill SJ. Distribution, properties, and functional characteristics of three classes of histamine receptor. Pharmacol Rev 1990; 42: 45-83.
16. Simons FER, McMillan JL, Simons KJ. A double-blind, single-dose, crossover comparison of cetirizine, terfenadine, loratadine, astemizole, and chlorpheniramine versus placebo: Suppressive effects on histamine-induced wheals and flares during 24 hours in normal subjects. J Allergy Clin Immunol 1990; 86: 540-7.
17. Grant JA, Danielson L, Rihoux J-P et al. A double-blind, single-dose, crossover comparison of cetirizine, ebastine, epinastine, fexofenadine, terfenadine, and loratadine versus placebo: suppression of histamine-induced wheal and flare response for 24 h in healthy male subjects. Allergy 1999; 54: 700-7.
18. Fadel R, Herpin-Richard N, Rihoux JP et al. Inhibitory effect of cetrizine 2HCL on eosinophil migration in vivo. Clin Allergy 1987; 17: 373-9.
19. Ishibashi Y, Kawashima M, Harada S et al. Phase I study of antiallergic agent, TAU-284 (bepotastine besilate): Study of inhibitory effect on intradermal reaction of histamine (in Japanese). Rinshoiyaku 1997; 13: 1187-97.
20. Monroe EW, Daly AF, Shalhoub RF. Appraisal of the validity of histamine-induced wheal and flare to predict the clinical efficacy of antihistamines. J Allergy Clin Immunol 1997; 99: S798-S806.
21. Eisen SA, Miller DK, Woodward RS et al. The effect of prescribed daily dose frequency on patient medication compliance. Arch Intern Med 1990; 150: 1881-4.
22. Hindmarch I, Shamsi Z, Antihistamines: models to assess sedative properties, assessment of sedation safety and other side effects. Clin Exp Allergy 1999; 29: 133-42.
23. Philpot EE. Safety of second generation antihistamines. Allerg Asthma Proc 2000; 21: 15-20.
24. Vermeeren A, O'Hanlon JF. Fexofenadine's effects, alone and with alcohol, on actual driving and psychomotor performance. J Allergy Clin Immunol 1998; 101: 306-11.
25. Welter JM, Bloomfield JR, Woodworth GG et al. Effects of fexofenadine, diphenhydramine, and alcohol on driving performance: a randomized, placebo-controled trial in the Iowa driving stimulator. Ann Intern Med 2000; 132: 354-63.
26. Nicholson AN, Stone BM, Turner C et al. Antihistamines and aircrew; usefulness of fexofenadine. Avit Space Environ Med 2000; 71: 2-6.