Identification of di-(2-ethylhexyl) phthalate-induced carboxylesterase 1 in C57BL/6 mouse liver microsomes: Purification, cDNA cloning, and baculovirus-mediated expression

Drug Metabolism and Disposition

Volumn 32, Issue 10, 2004, Pages 1170-1177

  Furihata, Tomomi ^a   Hosokawa, Masakiyo ^a   Koyano, Nao ^a   Nakamura, Takahiro ^a   Satoh, Tetsuo ^a   Chiba, Kan ^a  

^a CHIBA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYLESTERASE; CARBOXYLESTERASE 1; CARBOXYLESTERASE 1A; DIMER; ESTER DERIVATIVE; HYDROLASE; ISOENZYME; PHTHALIC ACID BIS(2 ETHYLHEXYL) ESTER; PRODRUG; TEMOCAPRIL; TEMOCAPRIL HYDROLASE; TRIMER; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL TISSUE; ANTIBODY SCREENING; ARTICLE; BACULOVIRUS EXPRESSION SYSTEM; CARBOXYLESTERASE 1 GENE; CONTROLLED STUDY; DNA LIBRARY; DRUG DISPOSITION; DRUG HYDROLYSIS; DRUG METABOLISM; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME PURIFICATION; ENZYME SPECIFICITY; ENZYME SUBUNIT; GENE; GENE EXPRESSION PROFILING; ISOELECTRIC POINT; LIVER MICROSOME; MOLECULAR CLONING; MOLECULAR WEIGHT; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; TISSUE HOMOGENATE;

AMINO ACID SEQUENCE; ANIMALS; CARBOXYLIC ESTER HYDROLASES; CLONING, MOLECULAR; DNA, COMPLEMENTARY; ENZYME INDUCTION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; MALE; MICE; MICE, INBRED C57BL; MICROSOMES, LIVER; MOLECULAR SEQUENCE DATA; PHTHALIC ACIDS; PHYLOGENY;

ANIMALIA; UNIDENTIFIED BACULOVIRUS;

EID: 4644273170     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: 10.1124/dmd.104.000620     Document Type: Article

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