Cyclooxygenase inhibition in human monocytes increases endotoxin-induced TNFα without affecting cyclooxygenase-2 expression

European Journal of Pharmacology

Volumn 501, Issue 1-3, 2004, Pages 9-17

  Ulcar, Ruth ^a   Peskar, Bernhard A ^a   Schuligoi, Rufina ^a   Heinemann, Akos ^a   Kessler, Harald H ^a   Santner, Brigitte I ^a   Amann, Rainer ^a  

^a MEDICAL UNIVERSITY OF GRAZ   (Austria)

Author keywords

Cyclooxygenase; Glucocorticoid; human; Monocyte; NSAID; Prostaglandin E 2; TNF

Indexed keywords

ACETYLSALICYLIC ACID; BUCLADESINE; CYCLIC AMP DERIVATIVE; CYCLOOXYGENASE 2; DEXAMETHASONE; ENDOTOXIN; INDOMETACIN; LYSINE ACETYLSALICYLATE; MESSENGER RNA; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN; PROSTAGLANDIN SYNTHASE INHIBITOR; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; BIOSYNTHESIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; HUMAN; HUMAN CELL; IC 50; MEMBRANE PERMEABILITY; MONOCYTE; NORMAL HUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; STATISTICAL SIGNIFICANCE;

CELLS, CULTURED; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTOXINS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MEMBRANE PROTEINS; MONOCYTES; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 4644240185     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2004.08.003     Document Type: Article

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