Identification of the structural and functional determinants of the extracellular domain of the human follicle stimulating hormone receptor

Journal of Endocrinology

Volumn 182, Issue 3, 2004, Pages 501-508

  Kene, P S ^b   Nalavadi, V C ^a   Dighe, R R ^a   Iyer, K S ^b   Mahale, S D ^b  

^a INDIAN INSTITUTE OF SCIENCE   (India)

^b Genetic Research Centre India   (India)

Author keywords

[No Author keywords available]

Indexed keywords

CARBONYL DERIVATIVE; CYCLIC AMP; FLUORINE DERIVATIVE; FOLLITROPIN; FOLLITROPIN RECEPTOR; METHYL GROUP; PEPTIDE DERIVATIVE;

ARTICLE; CELL SURFACE; COMPETITIVE INHIBITION; CONTROLLED STUDY; EXTRACELLULAR SPACE; HORMONE BINDING; HUMAN; HUMAN CELL; MODULATION; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PURIFICATION; SIGNAL TRANSDUCTION; SOLID; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; BINDING, COMPETITIVE; CYCLIC AMP; FEMALE; FOLLICLE STIMULATING HORMONE; HUMANS; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RADIOLIGAND ASSAY; RECEPTORS, FSH; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 4644239118     PISSN: 00220795     EISSN: None     Source Type: Journal    
DOI: 10.1677/joe.0.1820501     Document Type: Article

References (34)

1. Bradford MM 1976 A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Analytical Biochemistry 72 248-254.
2. Bramley TA & Ryan RJ 1978 Interactions of gonadotropins with corpus luteum membranes. VII. Association of hCG-binding and adenylate cyclase activities with rabbit corpus luteum plasma-membranes. Molecular and Cellular Endocrinology 12 319-325.
3. Braun T, Schofield PR & Sprengel R 1991 Amino terminal leucine-rich repeats in gonadotropin receptors determine hormone selectivity. EMBO Journal 10 1885-1890.
4. Brooker G, Harper JF, Terasaki WL & Moylan RD 1979 Radioimmunoassay of cyclic AMP and cyclic GMP. Advances in Cyclic Nucleotide Research 10 1-33.
5. Dattatreyamurty B & Reichert LE Jr 1992 A synthetic peptide corresponding to amino acids 9-30 of the extracellular domain of the follitropin (FSH) receptor specifically binds FSH. Molecular and Cellular Endocrinology 87 9-17.
6. Dattatreyamurty B & Reichert LE Jr 1993 Functional properties of polyclonal antibodies raised against the N-terminus region (residues 9-30) of the follicle-stimulating hormone (FSH) receptor: significance of this region in FSH recognition and signal transduction. Endocrinology 133 1593-1601.
7. Dias JA & Van Roey P 2001 Structural biology of human follitropin and its receptor. Archives of Medical Research 32 510-519.
8. Dias JA, Cohen B, Lindau-Shepard B, Nechamen CA, Peterson AJ & Schmidt A 2002 Molecular, structural and cellular biology of follitropin and follitropin receptor. Vitamins and Hormones 64 249-322.
9. Foulkes NS, Schlotter F, Pevet P & Sassone-Corsi P 1993 Pituitary hormone FSH directs the CREM functional switch during spermatogenesis. Nature 362 264-267.
10. Fraker PJ & Speck JC Jr 1978 Protein and cell membrane iodinations with a sparingly soluble chloroamide,1,3,4,6-tetrachloro-3a,6a-diphenylglycoluril. Biochemical and Biophysical Research Communications 80 849-857.
11. Jetly NM, Iyer KS, Hosur MV & Mahale SD 2003 Attempt to map the receptor binding sites of human follicle-stimulating hormone using disulfide peptides of its beta-subunit indicates major involvement of the regions around disulfide bonds Cys 28-Cys 82 and Cys 32-Cys 84 in receptor binding of the hormone. Journal of Peptide Research 62 269-279.
12. Ji I & Ji TH 1991 Exons 1-10 of the rat LH receptor encode a high affinity hormone binding site and exon 11 encodes G-protein modulation and a potential second hormone binding site. Endocrinology 128 2648-2650.
13. Jiang X, Dreano M, Buckler DR, Cheng S, Ythier A, Wu H, Hendrickson WA & Tayar NE 1995 Structural predictions for the ligand-binding region of the glycoprotein hormone receptors and the nature of hormone-receptor interactions. Structure 15 1341-1353.
14. Kobe B & Deisenhofer J 1994 The leucine-rich repeat: a versatile binding motif. Trends in Biochemical Sciences 19 415-421.
15. Krchnak V, Mach O & Maly A 1987 Computer prediction of potential immunogenic determinants from protein amino acid sequence. Analytical Biochemistry 165 200-207.
16. Leng N, Dattatreyamurty B & Reichert LE Jr 1995 Identification of amino acid residues 300-315 of the rat FSH receptor as a hormone binding domain: evidence for its interaction with specific regions of FSH beta-subunit. Biochemical and Biophysical Research Communications 210 392-399.
17. Lindau-Shepard B, Brumberg HA, Peterson AJ & Dias JA 2001 Reversible immunoneutralisation of the human follitropin receptor. Journal of Reproductive Immunology 49 1-19.
18. Liu X, Depasquale J, Griswold M & Dias JA 1994 Accessibility of rat and human follitropin receptor primary sequence (R265-S296) in situ. Endocrinology 135 682-691.
19. Liu X, Butterstein GM, Lindau-Shepard B, Brumberg HA & Dias JA 2000 An FSH receptor ectodomain that is a target for receptor immunoneutralisation yet does not affect ligand contact and activation. Endocrine 13 361-367.
20. Mahale SD, Cavanagh J, MacColl R, Schmidt A, Lindau-Shepard B & Dias JA 2001 Autologous biological response modification of gonadotropin receptor. Journal of Biological Chemistry 276 12410-12419.
21. Mann KI, Liu X & Dias JA 2000 Deletion of follicle-stimulating hormone (FSH) receptor residues encoded by exon one decreases FSH binding and signaling in rat. Biology of Reproduction 62 1240-1247.
22. McFarland KC, Sprengel R, Phillips HS, Kohler M, Rosemblit N, Nikolics K, Segaloff DL & Seeburg PH 1989 Lutropin-choriogonadotropin receptor: an unusual member of the G-protein coupled receptor family. Science 245 494-499.
23. Morris JC, Bergert ER & McCormick DJ 1993 Structure-function studies of the human thyrotropin receptor: inhibition of binding of labeled thyrotropin (TSH) by synthetic human TSH receptor peptides. Journal of Biological Chemistry 268 10900-10905.
24. Moyle WR, Campbell RK, Venkateswara Rao SN, Ayad NG, Bernard MP, Han Y & Wang Y 1995 Model of human chorionic gonadotropin and lutropin receptor interaction that explains signal transduction of the glycoprotein hormones. Journal of Biological Chemistry 270 20020-20031.
25. Nalavadi VC 2002 Structure-function studies on rat follicle stimulating hormone receptor using immunological probes. PhD thesis, Indian Institute of Science, Bangalore, India.
26. Nechamen CA & Dias JA 2000 Human follicle stimulating hormone receptor trafficking and hormone building sites in the amino terminus. Molecular and Cellular Endocrinology 166 101-110.
27. Reichert LE Jr & Dattatreyamurty B 1989 The follicle-stimulating hormone (FSH) receptor in testis: interaction with FSH, mechanism of signal transduction and properties of the purified receptor. Biology of Reproduction 40 13-26.
28. Richards JS 1980 Maturation of ovarian follicles: actions and interactions of pituitary and ovarian hormones on follicular cell differentiation. Physiological Reviews 60 51-89.
29. Roche PC, Ryan RJ & McCormick DJ 1992 Identification of hormone-binding regions of the human luteinising hormone/human chorionic gonadotropin receptor using synthetic peptides. Endocrinology 131 268-274.
30. Schmidt A, MacColl R, Lindau-Shepard B, Buckler D & Dias JA 2001 Accessibility and structural analysis of the purified soluble binding unit of follitropin receptor complexed with single chain follitropin. Journal of Biological Chemistry 276 23373-23381.
31. Selvaraj N & Moudgal NR 1993 Development of an LH receptor assay capable of measuring serum LH/CG in a wide variety of species. Journal of Reproduction and Fertility 98 611-616.
32. Sharma SC & Catterall JF 1995 Expression of the extracellular domain peptides of the FSH receptor and their effect on receptor-ligand interactions in vitro. Molecular and Cellular Endocrinology 115 87-93.
33. Shenoy AR, Srinivasan N, Subramaniam M & Visweswariah SS 2003 Mutational analysis of the Mycobacterium tuberculosis Rv1625c adenylyl cyclase: residues that confer nucleotide specificity contribute to dimerization. FEBS Letters 545 253-259.
34. Zijlstra-Westhoff WE, Slootstra JW, Pujik WC, Schaaper WMM, Oonk HB & Meloen RH 1998 In vitro inhibition of the bioactivity of follicle-stimulating hormone by antisera against a peptide representing part of the FSH-receptor. Journal of Reproductive Immunology 38 139-154.