In vitro inhibition of the bioactivity of follicle-stimulating hormone by antisera against a peptide representing part of the FSH-receptor

Journal of Reproductive Immunology

Volumn 38, Issue 2, 1998, Pages 139-154

  Zijlstra Westhoff, W E ^a   Slootstra, J W ^a   Puijk, W C ^a   Schaaper, W M M ^a   Oonk, H B ^a   Meloen, R H ^a  

^a WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

FSH; FSH receptor; FSH receptor binding domain; Inhibition of bioactivity; Peptide immunisation; Synthetic peptide vaccine

Indexed keywords

COMPLEMENT COMPONENT C5A; COMPLEMENT RECEPTOR; FOLLITROPIN; FOLLITROPIN RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; INTERLEUKIN 8; LUTEINIZING HORMONE RECEPTOR; PROTAMINE; THYROTROPIN RECEPTOR;

ANIMAL EXPERIMENT; ARTICLE; MALE; NONHUMAN; PRIORITY JOURNAL; RABBIT; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES; CELL LINE; CHO CELLS; CRICETINAE; FOLLICLE STIMULATING HORMONE; GTP-BINDING PROTEINS; HUMANS; MALE; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PROTAMINES; RABBITS; RECEPTORS, CELL SURFACE; RECEPTORS, FSH; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 0031830419     PISSN: 01650378     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-0378(98)00029-1     Document Type: Article

References (31)

1. Adashi, E.Y., Resnick, C.E., Rosenfeld, R.G., Powell, D.R., Koistinen, R., Rutanen, E.M., Seppala, M., 1994. Insulin-like growth factor (IGF) binding protein-1 is an antigonadotropin: evidence that optimal follicle-stimulating hormone action in ovarian granulosa cells is contingent upon amplification by endogenously-derived IGF's. In: LeRoith, D., Raizada, M.K. (Eds.), Series: Advances in Exp. Med. Biol. Plenum, New York, 343, pp. 377-385.
2. Braun T., Schofield P.R., Sprengel R. Amino-terminal leucine-rich repeats in gonadotropin receptors determine hormone selectivity. Embo J. 10:1991;1885-1890.
3. Dattatreyamurty B., Reichert L.E. A synthetic peptide corresponding to amino acids 9-30 of the extracellular domain of the follitropin (FSH) receptor specifically binds FSH. Mol. Cell. Endocrinol. 87:1992;9-17.
4. Dattatreyamurty B., Reichert L.R. Jr Functional properties of polyclonal antibodies raised against the N-terminus region (residues 9-30) of the follicle-stimulating hormone (FSH) receptor: significance of this receptor region in FSH recognition and signal transduction. Endocrinology. 133:1993;1593-1601.
5. DeMartino J.A., Van Riper G., Siciliano S.J., Molineaux C.J., Konteatis Z.D., Rosen H., Springers M.S. The amino terminus of the human C5a receptor is required for high affinity C5a binding and for receptor activation by C5a but not C5a analogs. J. Biol. Chem. 269:1994;14446-14450.
6. Dias J.A., Treble D.H., Reichert L.E. Jr Effect of bacitracin and polyamines on follicle-stimulating hormone binding to membrane-bound and detergent-solubilized bovine calf testis receptor. Endocrinology. 113:1983;2029-2034.
7. Fields C.G., Lloyd D.H., Macdonald R.L., Otteson K.M., Noble R.L. HBTU activation for automated Fmoc solid-phase peptide synthesis. Peptide Res. 4:1991;95-101.
8. Giudice L.C. Insulin-like growth factors and ovaian follicular development. Endocrinol. Rev. 13:1992;641-669.
9. Hébert C.A., Chuntharapai A., Smith M., Colby T., Kim J., Horuk R. Partial functional mapping of the human interleukin-8 type A receptor. J. Biol. Chem. 268:1993;19549-19553.
10. Horuk R. Molecular properties of the chemokine receptor family. Trends Pharmacol. Sci. 15:1994;159-165.
11. Horuk R. The interleukin-8-receptor family; from chemokines to malaria. Immunol. Today. 15:1994;169-174.
12. Ji I., Ji T.H. Human choriogonadotropin binds to a lutropin receptor with essentially no N-terminal extension and stimulates cAMP synthesis. J. Biol. Chem. 266:1991;13076-13079.
13. 397 is important for receptor activation. J. Biol. Chem. 268:1993;20851-20854.
14. Ji I., Zeng H., Ji T.H. Receptor activation of and signal generation by the lutropin/choriogonadotropin receptor. J. Biol. Chem. 268:1993;22971-22974.
15. Kumar T.J., Wang Y., Lu N., Matzuk M.M. Follicle stimulating hormone is required for ovarian follicle maturation but not male fertility. Nature Genet. 15:1997;201-204.
16. LaRosa G.J., Thomas K.M., Kaufmann M.E., Mark R., White M., Taylor L., Gray G., Witt D., Navarro J. Amino terminus of the interleukin-8 receptor is a major determinant of receptor subtype specificity. J. Biol. Chem. 267:1992;25402-25406.
17. Leinung M.C., Bergert E.R., McCormick D.M., Morris J.C. Synthetic analogs of the carboxyl-terminus of β-thyrotropin: the importance of basic amino acids in receptor binding activity. Biochemistry. 31:1992;10094-10098.
18. Leng N., Dattatreyamurty B., Reichert L.E. Jr Identification of amino acid residues 300-315 of the rat FSH receptor as a hormone binding domain: evidence for its interaction with specific regions of FSHβ-subunit. Biochem. Biophys. Res. Commun. 210:1995;392-399.
19. Liu X., DePasquale J.A., Griswold M.D., Dias J.A. Accessibility of rat and human follitropin receptor primary sequence R265-S296) in situ. Endocrinology. 135:1994;682-691.
20. Ohwaki K., Sakakibara R., Ishiguro M. Antibody against a peptide corresponding to the extracellular domain of the luteinizing hormone/chorionic gonadotropin receptor stimulates testosterone production in rat leydig cells. J. Biochem. 115:1994;596-601.
21. Opperman M., Readt U., Hebell T., Schmidt B., Zimmermann B., Götze O. Probing the human receptor for C5a anaphylatoxin with site-directed antibodies. J. Immunol. 151:1993;3785-3794.
22. Probst W.C., Snyder L.A., Schuster D.I., Brosius J., Sealfon S.C. Sequence alignment of the G-protein coupled receptor superfamily. DNA Cell Biol. 11:1992;1-20.
23. Schraufstätter I.U., Barritt D.S., Ma M., Oades Z.G., Cochrane C.G. Multiple sites on IL-8 responsible for binding to α and β IL-8 receptors. J. Immunol. 151:1993;6418-6428.
24. Sharma S.C., Catteral H.F. Expression of extracellular domain peptides of the FSH receptor and their effect on receptor-ligand interaction in vitro. Mol. Cell. Endocrinol. 115:1995;87-93.
25. Siciliano S.J., Rollins T.E., DeMartino J., Konteatis Z., Malkowitz L., Van Riper G., Bondy S., Rosen H., Springer M.S. Two-site binding of C5a by its receptor: an alternative binding paradigm for G-protein coupled receptors. Proc. Natl. Acad. Sci. USA. 91:1994;1214-1218.
26. Sprengel R., Braun T., Nikolics K., Segaloff D.L., Seeburg P.H. The testicular receptor for follicle stimulating hormone: structure and functional expression of cloned cDNA. Mol. Endocrinol. 4:1990;525-530.
27. Tanaka Y., Adams D.H., Shaw S. Proteoglycans on endothelial cells present adhesion-inducing cytokines to leucocytes. Immunol. Today. 14:1993;111-115.
28. Westhoff W.E., Slootstra J.W., Puijk W.C., Kuperus D., . Flinterman J.F., Schaaper W.M.M., Oonk H.B., Meloen R.H. Detection of epitopes on follicle-stimulating hormone and FSH-antiserum-induced suppression of bioactivity of follicle-stimulating hormone and luteinizing hormone. J. Reprod. Immunol. 30:1996;133-149.
29. Westhoff W.E., Slootstra J.W., Puijk W.C., Leeuwen van L., Schaaper W.M.M., Oonk H.B., Meloen R.H. In vitro inhibition of the biological activity of follicle-stimulating hormone by anti-peptide antisera representing the human follicle-stimulating hormone beta subunit sequence 33-53. Biol. Reprod. 56:1997;460-468.
30. Yadav S.P., Brew K., Majercik M.H., Puett D. A label selection approach to assess the role of individual amino groups in human choriogonadotropin receptor binding. J. Biol. Chem. 269:1994;3991-3998.
31. Yarney T.A., Sairam M.R., Khan H., Ravindranath N., Payne S., Seidah N.G. Molecular cloning and expression of the ovine testicular follicle stimulating hormone receptor. Mol. Cell. Endocrinol. 93:1993;219-226.