-
2
-
-
0037805547
-
RAS oncogenes: The frst 30 years
-
Malumbres,M. and Barbacid,M. (2003) RAS oncogenes: The frst 30 years. Nat. Rev. Cancer, 3, 459-465.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 459-465
-
-
Malumbres, M.1
Barbacid, M.2
-
3
-
-
0023620430
-
cKRAS mutations in human carcinomas occur preferentially in codon 12
-
Yanes,L., Groffen,J. and Valenzuela,D.M. (1987) cKRAS mutations in human carcinomas occur preferentially in codon 12. Oncogene, 1, 315-318.
-
(1987)
Oncogene
, vol.1
, pp. 315-318
-
-
Yanes, L.1
Groffen, J.2
Valenzuela, D.M.3
-
4
-
-
0025023573
-
Glycine to aspartic acid mutations at codon 13 of the c-Ki-ras gene in human gastrointestinal cancers
-
Nagata,Y., Abe,M., Kobayashi,K., Yoshida,K., Ishibashi,T., Naoe,T., Nakayama,E. and Shiku,H. (1990) Glycine to aspartic acid mutations at codon 13 of the c-Ki-ras gene in human gastrointestinal cancers. Cancer Res., 50, 480-482.
-
(1990)
Cancer Res
, vol.50
, pp. 480-482
-
-
Nagata, Y.1
Abe, M.2
Kobayashi, K.3
Yoshida, K.4
Ishibashi, T.5
Naoe, T.6
Nakayama, E.7
Shiku, H.8
-
5
-
-
46349083810
-
Blocking oncogenic Ras signaling for cancer therapy
-
Adjei,A.A. (2002) Blocking oncogenic Ras signaling for cancer therapy. J. Natl Cancer. Inst., 94, 1031-1032.
-
(2002)
J. Natl Cancer. Inst
, vol.94
, pp. 1031-1032
-
-
Adjei, A.A.1
-
6
-
-
3843084078
-
The COSMIC (Catalogue of Somatic Mutations in Cancer) database and website
-
Bamford,S., Dawson,E., Forbes,S., Clements,J., Pettett,R., Dogan,A., Flanagan,A., Teague,J., Futreal,P.A., Stratton,M.R. et al. (2004) The COSMIC (Catalogue of Somatic Mutations in Cancer) database and website. Br. J. Cancer, 91, 355-358.
-
(2004)
Br. J. Cancer
, vol.91
, pp. 355-358
-
-
Bamford, S.1
Dawson, E.2
Forbes, S.3
Clements, J.4
Pettett, R.5
Dogan, A.6
Flanagan, A.7
Teague, J.8
Futreal, P.A.9
Stratton, M.R.10
-
7
-
-
23244452962
-
Transcription inhibition of oncogenic KRAS by a mutation-selective peptide nucleic acid conjugated to the PKKKRKV nuclear localization signal peptide
-
Cogoi,S., Codognotto,A., Rapozzi,V., Meeuwenoord,N., van der Marel,G. and Xodo,L.E. (2005) Transcription inhibition of oncogenic KRAS by a mutation-selective peptide nucleic acid conjugated to the PKKKRKV nuclear localization signal peptide. Biochemistry, 44, 10510-10519.
-
(2005)
Biochemistry
, vol.44
, pp. 10510-10519
-
-
Cogoi, S.1
Codognotto, A.2
Rapozzi, V.3
Meeuwenoord, N.4
van der Marel, G.5
Xodo, L.E.6
-
8
-
-
0035125157
-
Antisense treatment directed against mutated Ki-ras in human colorectal adenocarcinoma
-
Andreyev,H.J.N., Ross,P.J., Cunningham,D. and Clarke,P.A. (2001) Antisense treatment directed against mutated Ki-ras in human colorectal adenocarcinoma. Gut, 48, 230-237.
-
(2001)
Gut
, vol.48
, pp. 230-237
-
-
Andreyev, H.J.N.1
Ross, P.J.2
Cunningham, D.3
Clarke, P.A.4
-
9
-
-
0033521860
-
Growth inhibition of human pancreatic cancer cell lines by anti-sense oligonucleotides specific to mutated K-ras genes
-
Kita,K., Saito,S., Morioka,C.Y. and Watanabe,A. (1999) Growth inhibition of human pancreatic cancer cell lines by anti-sense oligonucleotides specific to mutated K-ras genes. Int. J. Cancer, 80, 553-558.
-
(1999)
Int. J. Cancer
, vol.80
, pp. 553-558
-
-
Kita, K.1
Saito, S.2
Morioka, C.Y.3
Watanabe, A.4
-
10
-
-
0033168564
-
Enzymatic and antisense effects of a specific anti-Ki-ras ribozyme in vitro and in cell culture
-
Giannini,C.D., Roth,W.K., Piiper,A. and Zeuzem,S. (1999) Enzymatic and antisense effects of a specific anti-Ki-ras ribozyme in vitro and in cell culture. Nucleic Acids Res., 27, 2737-2744.
-
(1999)
Nucleic Acids Res
, vol.27
, pp. 2737-2744
-
-
Giannini, C.D.1
Roth, W.K.2
Piiper, A.3
Zeuzem, S.4
-
11
-
-
3142618386
-
Antiproliferative activity of a triplex-forming oligonucleotide recognizing a Ki-ras polypurine/polypyrimidine motif correlates with protein binding
-
Cogoi,S., Ballico,M., Bonora,G.M. and Xodo,L. (2004) Antiproliferative activity of a triplex-forming oligonucleotide recognizing a Ki-ras polypurine/polypyrimidine motif correlates with protein binding. Cancer Gene Ther., 11, 465-476.
-
(2004)
Cancer Gene Ther
, vol.11
, pp. 465-476
-
-
Cogoi, S.1
Ballico, M.2
Bonora, G.M.3
Xodo, L.4
-
12
-
-
0025194466
-
Inhibition of purified p21ras farnesyl:pRotein transferase by Cys-AAX tetrapeptides
-
Reiss,Y., Goldstein,J.L., Seabra,M.C., Casey,P.J. and Brown,M.S. (1990) Inhibition of purified p21ras farnesyl:pRotein transferase by Cys-AAX tetrapeptides. Cell, 62, 81-88.
-
(1990)
Cell
, vol.62
, pp. 81-88
-
-
Reiss, Y.1
Goldstein, J.L.2
Seabra, M.C.3
Casey, P.J.4
Brown, M.S.5
-
13
-
-
26444574802
-
Development of farnesyl transferase inhibitors: A review
-
Appels,N.M., Beijnen,J.H. and Schellens,J.H. (2005) Development of farnesyl transferase inhibitors: A review. Oncologist, 10, 565-578.
-
(2005)
Oncologist
, vol.10
, pp. 565-578
-
-
Appels, N.M.1
Beijnen, J.H.2
Schellens, J.H.3
-
14
-
-
12644268252
-
Sequence-specific antitumor activity of a phosphorothioate oligodeoxyribonucleotide targeted to human C-raf kinase supports an antisense mechanism of action in vivo
-
Monia,B.P., Sasmor,H., Johnston,J.F., Freier,S.M., Lesnik,E.A., Muller,M., Geiger,T., Altmann,K.H., Moser,H. and Fabbro,D. (1996) Sequence-specific antitumor activity of a phosphorothioate oligodeoxyribonucleotide targeted to human C-raf kinase supports an antisense mechanism of action in vivo. Proc. Natl Acad. Sci. USA, 93, 15481-15484.
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 15481-15484
-
-
Monia, B.P.1
Sasmor, H.2
Johnston, J.F.3
Freier, S.M.4
Lesnik, E.A.5
Muller, M.6
Geiger, T.7
Altmann, K.H.8
Moser, H.9
Fabbro, D.10
-
15
-
-
0032984348
-
Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo
-
Sebolt-Leopold,J.S., Dudley,D.T., Herrera,R., Van Becelaere,K., Wiland,A., Gowan,R.C., Tecle,H., Barrett,S.D., Bridges,A., Przybranowski,S. et al. (1999) Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo. Nat. Med., 810-816.
-
(1999)
Nat. Med
, pp. 810-816
-
-
Sebolt-Leopold, J.S.1
Dudley, D.T.2
Herrera, R.3
Van Becelaere, K.4
Wiland, A.5
Gowan, R.C.6
Tecle, H.7
Barrett, S.D.8
Bridges, A.9
Przybranowski, S.10
-
16
-
-
0024214210
-
Characterization of the human c-K-ras gene promoter
-
Yamamoto,F. and Perucho,M. (1988) Characterization of the human c-K-ras gene promoter. Oncogene Res., 3, 125-130.
-
(1988)
Oncogene Res
, vol.3
, pp. 125-130
-
-
Yamamoto, F.1
Perucho, M.2
-
17
-
-
0023057003
-
Chromatin structure of the promoter region of the human c-K-ras gene
-
Jordano,J. and Perucho,M. (1986) Chromatin structure of the promoter region of the human c-K-ras gene. Nucleic Acids Res., 14, 7361-7378.
-
(1986)
Nucleic Acids Res
, vol.14
, pp. 7361-7378
-
-
Jordano, J.1
Perucho, M.2
-
18
-
-
0023895399
-
Initial characterization of a potential transcriptional enhancer for the human c-K-ras gene
-
Jordano,J. and Perucho,M. (1988) Initial characterization of a potential transcriptional enhancer for the human c-K-ras gene. Oncogene, 2, 359-366.
-
(1988)
Oncogene
, vol.2
, pp. 359-366
-
-
Jordano, J.1
Perucho, M.2
-
19
-
-
0023899769
-
Nuclease hypersensitive sites in chromatin
-
Gross,D.S. and Garrard,W.T. (1988) Nuclease hypersensitive sites in chromatin. Annu. Rev. Biochem., 57, 159-197.
-
(1988)
Annu. Rev. Biochem
, vol.57
, pp. 159-197
-
-
Gross, D.S.1
Garrard, W.T.2
-
20
-
-
0023802737
-
Site-specific oligonucleotide binding represses transcription of the human c-CMYC gene in vitro
-
Cooney,M., Czernuszewicz,G., Postel,E.H., Flint,S.J. and Hogan,M.E. (1988) Site-specific oligonucleotide binding represses transcription of the human c-CMYC gene in vitro. Science, 241, 456-459.
-
(1988)
Science
, vol.241
, pp. 456-459
-
-
Cooney, M.1
Czernuszewicz, G.2
Postel, E.H.3
Flint, S.J.4
Hogan, M.E.5
-
21
-
-
0037015078
-
Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-CMYC transcription
-
Siddiqui-Jain,A., Grand,C.L., Bearss,D.J. and Hurley,L.H. (2002) Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-CMYC transcription. Proc. Natl Acad. Sci. USA, 99, 11593-11598.
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 11593-11598
-
-
Siddiqui-Jain, A.1
Grand, C.L.2
Bearss, D.J.3
Hurley, L.H.4
-
22
-
-
0032030327
-
DNA tetraplex formation in the control region of c-CMYC
-
Simonsson,T., Pecinka,P. and Kubista,M. (1998) DNA tetraplex formation in the control region of c-CMYC. Nucleic Acids Res., 26, 1167-1172.
-
(1998)
Nucleic Acids Res
, vol.26
, pp. 1167-1172
-
-
Simonsson, T.1
Pecinka, P.2
Kubista, M.3
-
23
-
-
33744472232
-
G-quadruplex formation within the promoter of the KRAS proto-oncogene and its effect on transcription
-
Cogoi,S. and Xodo,L.E. (2006) G-quadruplex formation within the promoter of the KRAS proto-oncogene and its effect on transcription. Nucleic Acids Res., 34, 2536-2549.
-
(2006)
Nucleic Acids Res
, vol.34
, pp. 2536-2549
-
-
Cogoi, S.1
Xodo, L.E.2
-
24
-
-
33646462913
-
Deconvoluting the structural and drug-recognition complexity of the G-quadruplexforming region upstream of the bcl-2 P1 promoter
-
Dexheimer,T.S., Sun,D. and Hurley,L.H. (2006) Deconvoluting the structural and drug-recognition complexity of the G-quadruplexforming region upstream of the bcl-2 P1 promoter. J. Am. Chem. Soc., 128, 5404-5415.
-
(2006)
J. Am. Chem. Soc
, vol.128
, pp. 5404-5415
-
-
Dexheimer, T.S.1
Sun, D.2
Hurley, L.H.3
-
25
-
-
28944442742
-
Evidence for the presence of a guanine quadruplex forming region within a polypurine tract of the hypoxia inducible factor 1alpha promoter
-
De Armond,R., Wood,S., Sun,D., Hurley,L.H. and Ebbinghaus,S.W. (2005) Evidence for the presence of a guanine quadruplex forming region within a polypurine tract of the hypoxia inducible factor 1alpha promoter. Biochemistry, 44, 16341-16350.
-
(2005)
Biochemistry
, vol.44
, pp. 16341-16350
-
-
De Armond, R.1
Wood, S.2
Sun, D.3
Hurley, L.H.4
Ebbinghaus, S.W.5
-
26
-
-
27244435211
-
Facilitation of a structural transition in the polypurine-polypyrimidine tract within the proximal promoter region of the human VEGF gene by the presence of potassium and G-quadruplex interactive agents
-
Sun,D., Guo,K., Rusche,J.J. and Hurley,L.H. (2005) Facilitation of a structural transition in the polypurine-polypyrimidine tract within the proximal promoter region of the human VEGF gene by the presence of potassium and G-quadruplex interactive agents. Nucleic Acids Res., 33, 6070-6080.
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 6070-6080
-
-
Sun, D.1
Guo, K.2
Rusche, J.J.3
Hurley, L.H.4
-
27
-
-
38049017592
-
Characterization of the G-quadruplexes in the duplex nuclease hypersensitive element of the PDGF-A promoter and modulation of the PDGF-A promoter activity by TMPyP4
-
Qin,Y., REzler,E.M., Gokhale,V., Sun,D. and Hurley,L.H. (2007) Characterization of the G-quadruplexes in the duplex nuclease hypersensitive element of the PDGF-A promoter and modulation of the PDGF-A promoter activity by TMPyP4. Nucl. Acids Res., 35, 76698-76713.
-
(2007)
Nucl. Acids Res
, vol.35
, pp. 76698-76713
-
-
Qin, Y.1
REzler, E.M.2
Gokhale, V.3
Sun, D.4
Hurley, L.H.5
-
28
-
-
34247160470
-
Structure of an unprecedented G-quadruplex scaffold in the human c-kit promoter
-
Phan,A.T., Kuryavyi,V., Burge,S., Neidle,S. and Patel,D.J. (2007) Structure of an unprecedented G-quadruplex scaffold in the human c-kit promoter. J. Am. Chem. Soc., 129, 4386-4392.
-
(2007)
J. Am. Chem. Soc
, vol.129
, pp. 4386-4392
-
-
Phan, A.T.1
Kuryavyi, V.2
Burge, S.3
Neidle, S.4
Patel, D.J.5
-
29
-
-
20144373479
-
Formation and properties of hairpin and tetraplex structures of guanine-rich regulatory sequences of muscle-specific genes
-
Yafe,A., Etzioni,S., Weisman-Shomer,P. and Fry,M. (2005) Formation and properties of hairpin and tetraplex structures of guanine-rich regulatory sequences of muscle-specific genes. Nucleic Acids Res., 33, 2887-2900.
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 2887-2900
-
-
Yafe, A.1
Etzioni, S.2
Weisman-Shomer, P.3
Fry, M.4
-
30
-
-
33748519569
-
Gene function correlates with potential for G4 DNA formation in the human genome
-
Eddy,J. and Maizels,N. (2006) Gene function correlates with potential for G4 DNA formation in the human genome. Nucleic Acids Res., 34, 3887-3896.
-
(2006)
Nucleic Acids Res
, vol.34
, pp. 3887-3896
-
-
Eddy, J.1
Maizels, N.2
-
31
-
-
33846928449
-
G-quadruplexes in promoters throughout the human genome
-
Huppert,J.L. and Balasubramanian,S. (2007) G-quadruplexes in promoters throughout the human genome. Nucleic Acids Res., 35, 406-413.
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 406-413
-
-
Huppert, J.L.1
Balasubramanian, S.2
-
32
-
-
34347273762
-
Tetraplex DNA and its interacting proteins
-
Fry,M. (2007) Tetraplex DNA and its interacting proteins. Front Biosci., 12, 4336-4351.
-
(2007)
Front Biosci
, vol.12
, pp. 4336-4351
-
-
Fry, M.1
-
33
-
-
46349094442
-
-
Abmayr,S.M. and Worman,J.L. (1993) Current Protocols in Molecular Biology. John Wiley and Sons, pp. 12.1.1-12.1.6.
-
Abmayr,S.M. and Worman,J.L. (1993) Current Protocols in Molecular Biology. John Wiley and Sons, pp. 12.1.1-12.1.6.
-
-
-
-
34
-
-
28044456518
-
Nerve influence on myosin light chain phosphorilation in slow and fast skeletal muscles
-
Bozzo,C, Spolaore,B., Toniolo,L., Stevens,L., Bastide,B., Cieniewski-Bernard,C., Fontana,A., Mounier,Y. and Reggiani,C. (2005) Nerve influence on myosin light chain phosphorilation in slow and fast skeletal muscles. FEBS, 272, 5771-5785.
-
(2005)
FEBS
, vol.272
, pp. 5771-5785
-
-
Bozzo, C.1
Spolaore, B.2
Toniolo, L.3
Stevens, L.4
Bastide, B.5
Cieniewski-Bernard, C.6
Fontana, A.7
Mounier, Y.8
Reggiani, C.9
-
35
-
-
0033434080
-
Probability-based protein identification by searching sequence databases using mass spectrometry data
-
Perkins,D.N., Pappin,D.J., Creasy,D.M. and Cottrell,J.S. (1999) Probability-based protein identification by searching sequence databases using mass spectrometry data. Electrophoresis, 20, 3551-3567.
-
(1999)
Electrophoresis
, vol.20
, pp. 3551-3567
-
-
Perkins, D.N.1
Pappin, D.J.2
Creasy, D.M.3
Cottrell, J.S.4
-
36
-
-
14844317697
-
Stabilization of guanine quadruplex DNA by the binding of porphyrins with cationic side arms
-
Yamashita,T., Uno,T. and Ishikawa,Y. (2005) Stabilization of guanine quadruplex DNA by the binding of porphyrins with cationic side arms. Bioorg. Med. Chem., 13, 2423-2430.
-
(2005)
Bioorg. Med. Chem
, vol.13
, pp. 2423-2430
-
-
Yamashita, T.1
Uno, T.2
Ishikawa, Y.3
-
37
-
-
0035913742
-
Selective interactions of cationic porphyrins with G-quadruplex structures
-
Han,H., Langley,D.R., Rangan,A. and Hurley,L.H. (2001) Selective interactions of cationic porphyrins with G-quadruplex structures. J. Am. Chem. Soc., 123, 8902-8913.
-
(2001)
J. Am. Chem. Soc
, vol.123
, pp. 8902-8913
-
-
Han, H.1
Langley, D.R.2
Rangan, A.3
Hurley, L.H.4
-
38
-
-
27144440078
-
Thermal difference spectra: A specific signature for nucleic acid structures
-
Mergny,J.L., Li,J., Lacroix,L., Amrane,S. and Chaires,J.B. (2005) Thermal difference spectra: A specific signature for nucleic acid structures. Nucleic Acids Res., 33, e138.
-
(2005)
Nucleic Acids Res
, vol.33
-
-
Mergny, J.L.1
Li, J.2
Lacroix, L.3
Amrane, S.4
Chaires, J.B.5
-
39
-
-
33644833219
-
Small-molecule interaction with a five-guanine-tract G-quadruplex structure from the human MYC promoter
-
Phan,A.T., Kuryavyi,V., Gaw,H.Y. and Patel,D.J. (2005) Small-molecule interaction with a five-guanine-tract G-quadruplex structure from the human MYC promoter. Nat. Chem. Biol., 1, 167-173.
-
(2005)
Nat. Chem. Biol
, vol.1
, pp. 167-173
-
-
Phan, A.T.1
Kuryavyi, V.2
Gaw, H.Y.3
Patel, D.J.4
-
40
-
-
17144371894
-
Vertebrate telomere repeat DNAs favor external loop propeller quadruplex structures in the presence of high concentrations of potassium
-
Rujan,I.N., Meleney,J.C. and Bolton,P.H. (2005) Vertebrate telomere repeat DNAs favor external loop propeller quadruplex structures in the presence of high concentrations of potassium. Nucleic Acids Res., 33, 2022-2031.
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 2022-2031
-
-
Rujan, I.N.1
Meleney, J.C.2
Bolton, P.H.3
-
41
-
-
0035793647
-
Fluorescence resonance energy transfer as a probe for G-quartet formation by a telomeric repeat
-
Mergny,J.L. and Maurizot,J.C. (2001) Fluorescence resonance energy transfer as a probe for G-quartet formation by a telomeric repeat. Chembiochem., 2, 124-132.
-
(2001)
Chembiochem
, vol.2
, pp. 124-132
-
-
Mergny, J.L.1
Maurizot, J.C.2
-
42
-
-
0036567249
-
Effect of primary and secondary structure of oligodeoxyribonucleotides on the fluorescent properties of conjugated dyes
-
Nazarenko,I., Pires,R., Lowe,B., Obaidy,M. and Rashtchian,A. (2002) Effect of primary and secondary structure of oligodeoxyribonucleotides on the fluorescent properties of conjugated dyes. Nucleic Acids Res. 30, 2089-2195.
-
(2002)
Nucleic Acids Res
, vol.30
, pp. 2089-2195
-
-
Nazarenko, I.1
Pires, R.2
Lowe, B.3
Obaidy, M.4
Rashtchian, A.5
-
43
-
-
33750988204
-
G-quadruplex-based FRET probes with the thrombin-binding aptamer (TBA) sequence designed for the efficient fluorometric detection of the potassium ion
-
Nagatoishi,S., Nojima,T., Galezowska,E., Juskowiaak,B. and Takenaka,S. (2006) G-quadruplex-based FRET probes with the thrombin-binding aptamer (TBA) sequence designed for the efficient fluorometric detection of the potassium ion. ChemBioChem., 7, 1730-1737.
-
(2006)
ChemBioChem
, vol.7
, pp. 1730-1737
-
-
Nagatoishi, S.1
Nojima, T.2
Galezowska, E.3
Juskowiaak, B.4
Takenaka, S.5
-
44
-
-
34247641796
-
Fluorescence-based melting assays for studying quadruplex ligands
-
De Cian,A., Guittat,L., Kaiser,M., Sacca,B., Amrane,S., Bourdoncle,A., Alberti,P., Teulade-Fichou,M., Lacroix,L. and Mergny,J.L. (2007) Fluorescence-based melting assays for studying quadruplex ligands. Methods, 42, 183-195.
-
(2007)
Methods
, vol.42
, pp. 183-195
-
-
De Cian, A.1
Guittat, L.2
Kaiser, M.3
Sacca, B.4
Amrane, S.5
Bourdoncle, A.6
Alberti, P.7
Teulade-Fichou, M.8
Lacroix, L.9
Mergny, J.L.10
-
45
-
-
35448944443
-
Quadruplex melting
-
Rachwal,P.A. and Fox,K.R. (2007) Quadruplex melting. Methods, 43, 291-301.
-
(2007)
Methods
, vol.43
, pp. 291-301
-
-
Rachwal, P.A.1
Fox, K.R.2
-
46
-
-
3242666778
-
Propeller-type parallel-stranded G-quadruplexes in the human c-myc promoter
-
Phan,A.T., Modi,Y.S. and Patel,D.J. (2004) Propeller-type parallel-stranded G-quadruplexes in the human c-myc promoter. J. Am. Chem. Soc., 126, 8710-8716.
-
(2004)
J. Am. Chem. Soc
, vol.126
, pp. 8710-8716
-
-
Phan, A.T.1
Modi, Y.S.2
Patel, D.J.3
-
47
-
-
31944444804
-
An intramolecular G-quadruplex structure with mixed parallel/antiparallel G-strands formed in the human BCL-2 promoter region in solution
-
Dai,J., Dexheimer,T.S., Chen,D., Carver,M., Ambrus,A., Jones,R.A. and Yang,D. (2006) An intramolecular G-quadruplex structure with mixed parallel/antiparallel G-strands formed in the human BCL-2 promoter region in solution. J. Am. Chem. Soc., 128, 1096-1098.
-
(2006)
J. Am. Chem. Soc
, vol.128
, pp. 1096-1098
-
-
Dai, J.1
Dexheimer, T.S.2
Chen, D.3
Carver, M.4
Ambrus, A.5
Jones, R.A.6
Yang, D.7
-
48
-
-
20044382992
-
Design and synthesis of an expanded porphyrin that has selectivity for the c-MYC G-quadruplex structure
-
Seenisamy,J., Bashyam,S., Gokhale,V., Vankayalapati,H., Sun,D., Siddiqui-Jain,A., Streiner,N., Shin-Ya,K., White,E., Wilson,W.D. et al. (2005) Design and synthesis of an expanded porphyrin that has selectivity for the c-MYC G-quadruplex structure. J. Am. Chem. Soc., 127, 2944-2959.
-
(2005)
J. Am. Chem. Soc
, vol.127
, pp. 2944-2959
-
-
Seenisamy, J.1
Bashyam, S.2
Gokhale, V.3
Vankayalapati, H.4
Sun, D.5
Siddiqui-Jain, A.6
Streiner, N.7
Shin-Ya, K.8
White, E.9
Wilson, W.D.10
-
49
-
-
3242691283
-
The dynamic character of the G-quadruplex element in the c-MYC promoter and modification by TMPyP4
-
Seenisamy,J., Rezler,E.M., Powell,T.J., Tye,D., Gokhale,V., Joshi,C.S., Siddiqui-Jain,A. and Hurley,L.H. (2004) The dynamic character of the G-quadruplex element in the c-MYC promoter and modification by TMPyP4. J. Am. Chem. Soc., 126, 8702-8709.
-
(2004)
J. Am. Chem. Soc
, vol.126
, pp. 8702-8709
-
-
Seenisamy, J.1
Rezler, E.M.2
Powell, T.J.3
Tye, D.4
Gokhale, V.5
Joshi, C.S.6
Siddiqui-Jain, A.7
Hurley, L.H.8
-
50
-
-
4444285877
-
Formation of an interlocked quadruplex dimer by d(GGGT)
-
Krishnan-Ghosh,Y., Liu,D. and Balasubramanian,S. (2004) Formation of an interlocked quadruplex dimer by d(GGGT). J. Am. Chem. Soc., 126 11009-11016.
-
(2004)
J. Am. Chem. Soc
, vol.126
, pp. 11009-11016
-
-
Krishnan-Ghosh, Y.1
Liu, D.2
Balasubramanian, S.3
-
51
-
-
33644547652
-
Synthesis and characterization of DNA quadruplexes containing T-tetrads formed by bunch-oligonucleotides
-
Oliviero,G., Amato,J., Borbone,N., Galeone,A., Varra,M., Piccialli,G. and Mayol,L. (2006) Synthesis and characterization of DNA quadruplexes containing T-tetrads formed by bunch-oligonucleotides. Biopolymers 81, 194-201.
-
(2006)
Biopolymers
, vol.81
, pp. 194-201
-
-
Oliviero, G.1
Amato, J.2
Borbone, N.3
Galeone, A.4
Varra, M.5
Piccialli, G.6
Mayol, L.7
-
52
-
-
0035812604
-
Dimeric DNA quadruplex containing major groove-aligned A-T-A-T and G-C-G-C tetrads stabilized by inter-subunit Watson-Crick A-T and G-C pairs
-
Zhang,N., Gorin,A., Majumdar,A., Kettani,A., Chernichenko,N., Skripkin,E. and Patel,D.J. (2001) Dimeric DNA quadruplex containing major groove-aligned A-T-A-T and G-C-G-C tetrads stabilized by inter-subunit Watson-Crick A-T and G-C pairs. J. Mol. Biol., 312, 1073-1088.
-
(2001)
J. Mol. Biol
, vol.312
, pp. 1073-1088
-
-
Zhang, N.1
Gorin, A.2
Majumdar, A.3
Kettani, A.4
Chernichenko, N.5
Skripkin, E.6
Patel, D.J.7
-
53
-
-
38849085810
-
A sequence-independent study of the influence of short loop lengths on the stability and topology of intramolecular DNA G-quadruplexes
-
Bugaut,A. and Balasubramanian,S. (2007) A sequence-independent study of the influence of short loop lengths on the stability and topology of intramolecular DNA G-quadruplexes. Biochemistry, 47, 689-697.
-
(2007)
Biochemistry
, vol.47
, pp. 689-697
-
-
Bugaut, A.1
Balasubramanian, S.2
-
54
-
-
33847675742
-
Structural basis for binding of porhyrins to human telomeres
-
Parkinson,G.N., Ghosh,R. and Neidle,S. (2007) Structural basis for binding of porhyrins to human telomeres. Biochemistry, 46, 2390-2397.
-
(2007)
Biochemistry
, vol.46
, pp. 2390-2397
-
-
Parkinson, G.N.1
Ghosh, R.2
Neidle, S.3
-
55
-
-
0036790810
-
Unfolding of quadruplex structure in the G-rich strand of the minisatellite repeat by the binding protein 1UP1
-
Fukuda,H., Katahira,M., Tsuchiya,N., Enokizono,Y., Sugimura,T., Nagao,M. and Nakagama,H. (2002) Unfolding of quadruplex structure in the G-rich strand of the minisatellite repeat by the binding protein 1UP1. Proc. Natl Acad. Sci. USA, 99, 12685-12690.
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 12685-12690
-
-
Fukuda, H.1
Katahira, M.2
Tsuchiya, N.3
Enokizono, Y.4
Sugimura, T.5
Nagao, M.6
Nakagama, H.7
-
56
-
-
0035913742
-
Selective interactions of cationic porphyrins with G-quadruplex
-
Han,H., Langley,D.R., Raangan,A. and Hurley,L.H. (2001) Selective interactions of cationic porphyrins with G-quadruplex. J. Am. Chem. Soc., 123, 8902-8913.
-
(2001)
J. Am. Chem. Soc
, vol.123
, pp. 8902-8913
-
-
Han, H.1
Langley, D.R.2
Raangan, A.3
Hurley, L.H.4
-
57
-
-
30444461518
-
Synthesis and biological evaluation of new pentaphyrin macrocycles for photodynamic therapy
-
Comuzzi,C., Cogoi,S., Overhand,M., van der Marel,G.A., Overkleeft,H.S. and Xodo,L.E. (2006) Synthesis and biological evaluation of new pentaphyrin macrocycles for photodynamic therapy. J. Med. Chem., 49, 196-204.
-
(2006)
J. Med. Chem
, vol.49
, pp. 196-204
-
-
Comuzzi, C.1
Cogoi, S.2
Overhand, M.3
van der Marel, G.A.4
Overkleeft, H.S.5
Xodo, L.E.6
-
58
-
-
0038682011
-
PARP goes transcription
-
Kraus,W.L. and Lis,J.T. (2003) PARP goes transcription. Cell, 113, 677-683.
-
(2003)
Cell
, vol.113
, pp. 677-683
-
-
Kraus, W.L.1
Lis, J.T.2
-
59
-
-
17944385649
-
Activation of Reg gene, a gene for insulin-producing beta -cell regeneration: Poly(ADP-ribose) polymerase binds Reg promoter and regulates the transcription by autopoly(ADP-ribosyl)ation
-
Akiyama,T., Takasawa,S., Nata,K., Kobayashi,S., Abe,M., Shervani,N.J., Ikeda,T., Nakagawa,K., Unno,M., Matsuno,S. et al. (2001) Activation of Reg gene, a gene for insulin-producing beta -cell regeneration: Poly(ADP-ribose) polymerase binds Reg promoter and regulates the transcription by autopoly(ADP-ribosyl)ation. Proc. Natl Acad. Sci. USA, 98, 48-53.
-
(2001)
Proc. Natl Acad. Sci. USA
, vol.98
, pp. 48-53
-
-
Akiyama, T.1
Takasawa, S.2
Nata, K.3
Kobayashi, S.4
Abe, M.5
Shervani, N.J.6
Ikeda, T.7
Nakagawa, K.8
Unno, M.9
Matsuno, S.10
-
60
-
-
17144423943
-
Specific binding of poly(ADP-ribose) polymerase-1 to cruciform hairpins
-
Potaman,V.N., Shlyakhtenko,L.S., Oussatcheva,E.A., Lyubchenko,Y.L. and Soldatenkov,V.A. (2005) Specific binding of poly(ADP-ribose) polymerase-1 to cruciform hairpins. J. Mol. Biol., 348, 609-615.
-
(2005)
J. Mol. Biol
, vol.348
, pp. 609-615
-
-
Potaman, V.N.1
Shlyakhtenko, L.S.2
Oussatcheva, E.A.3
Lyubchenko, Y.L.4
Soldatenkov, V.A.5
-
61
-
-
27644450261
-
DNA transitions induced by binding of PARP-1 to cruciform structures in supercoiled plasmids
-
Chasovskikh,S., Dimtchev,A., Smulson,M. and Dritschilo,A. (2005) DNA transitions induced by binding of PARP-1 to cruciform structures in supercoiled plasmids. Cytometry A., 68, 21-27.
-
(2005)
Cytometry A
, vol.68
, pp. 21-27
-
-
Chasovskikh, S.1
Dimtchev, A.2
Smulson, M.3
Dritschilo, A.4
-
62
-
-
0034011881
-
Ku antoantigen: A multifunctional DNA-binding protein
-
Tuteja,R. and Tuteja,N. (2000) Ku antoantigen: A multifunctional DNA-binding protein. Crit. Rev. Biochem. Mol. Biol., 35, 1-33.
-
(2000)
Crit. Rev. Biochem. Mol. Biol
, vol.35
, pp. 1-33
-
-
Tuteja, R.1
Tuteja, N.2
-
63
-
-
0029988716
-
Sequence-specific DNA binding by Ku autoantigen and its effects on transcription
-
Giffin,W., Torrance,H., Rodda,D.J., Prefontaine,G.G., Pope,L. and Hache,R.J. (1996) Sequence-specific DNA binding by Ku autoantigen and its effects on transcription. Nature, 380, 265-268.
-
(1996)
Nature
, vol.380
, pp. 265-268
-
-
Giffin, W.1
Torrance, H.2
Rodda, D.J.3
Prefontaine, G.G.4
Pope, L.5
Hache, R.J.6
-
64
-
-
0027156140
-
EBP-80, a transcription factor closely resembling the human autoantigen Ku, recognizes single- to double-strand transitions in DNA
-
Falzon,M., Fewell,J.W. and Kuf,E.L. (1993) EBP-80, a transcription factor closely resembling the human autoantigen Ku, recognizes single- to double-strand transitions in DNA. J. Biol. Chem., 268, 10546-10552.
-
(1993)
J. Biol. Chem
, vol.268
, pp. 10546-10552
-
-
Falzon, M.1
Fewell, J.W.2
Kuf, E.L.3
-
65
-
-
0034693066
-
Human Ku antigen tightly binds and stabilizes a tetrahelical form of the Fragile X syndrome d(CGG)n expanded sequence
-
Uliel,L., Weisman-Shomer,P., Oren-Jazan,H., Newcomb,T., Loeb,L.A. and Fry,M. (2000) Human Ku antigen tightly binds and stabilizes a tetrahelical form of the Fragile X syndrome d(CGG)n expanded sequence. J. Biol. Chem., 275, 33134-33141.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 33134-33141
-
-
Uliel, L.1
Weisman-Shomer, P.2
Oren-Jazan, H.3
Newcomb, T.4
Loeb, L.A.5
Fry, M.6
-
66
-
-
0142242183
-
Structure-based incorporation of 6-methyl-8-(2-deoxy-beta-ribofuranosyl) isoxanthopteridine into the human telomeric repeat DNA as a probe for UP1 binding and destabilization of G-tetrad structures
-
Myers,J.C., Moore,S.A. and Shamoo,Y. (2003) Structure-based incorporation of 6-methyl-8-(2-deoxy-beta-ribofuranosyl) isoxanthopteridine into the human telomeric repeat DNA as a probe for UP1 binding and destabilization of G-tetrad structures. J. Biol. Chem., 278, 42300-42306.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 42300-42306
-
-
Myers, J.C.1
Moore, S.A.2
Shamoo, Y.3
-
67
-
-
0038641860
-
A proteomic approach to the identification of heterogeneous nuclear ribonucleoproteins as a new family of poly(ADP-ribose)-binding proteins
-
Gagné,J.P., Hunter,J.M., Labrecque,B., Chabot,B. and Poirier,G.G. (2003) A proteomic approach to the identification of heterogeneous nuclear ribonucleoproteins as a new family of poly(ADP-ribose)-binding proteins. Biochem. J., 371, 331-340.
-
(2003)
Biochem. J
, vol.371
, pp. 331-340
-
-
Gagné, J.P.1
Hunter, J.M.2
Labrecque, B.3
Chabot, B.4
Poirier, G.G.5
-
68
-
-
0029917052
-
Heterogeneous nuclear ribonucleoprotein K is a transcription factor
-
Michelotti,E.F., Michelotti,G.A., Aronsohn,A.I. and Levens,D. (1996) Heterogeneous nuclear ribonucleoprotein K is a transcription factor. Mol. Cell Biol., 16, 2350-2360.
-
(1996)
Mol. Cell Biol
, vol.16
, pp. 2350-2360
-
-
Michelotti, E.F.1
Michelotti, G.A.2
Aronsohn, A.I.3
Levens, D.4
-
69
-
-
35848942604
-
Trisubstituted isoalloxazines as a new class of G-quadruplex binding ligands: Small molecule regulation of c-kit oncogene expression
-
Bejugam,M., Sewitz,S., Shirude,P.S., Rodriguez,R., Shahid,R. and Balasubramanian,S. (2007) Trisubstituted isoalloxazines as a new class of G-quadruplex binding ligands: Small molecule regulation of c-kit oncogene expression. J. Am. Chem. Soc., 129, 12926-12927.
-
(2007)
J. Am. Chem. Soc
, vol.129
, pp. 12926-12927
-
-
Bejugam, M.1
Sewitz, S.2
Shirude, P.S.3
Rodriguez, R.4
Shahid, R.5
Balasubramanian, S.6
-
70
-
-
46349088975
-
Erik B. Design of twisted intercalating nucleic acids (TINA) forming antiparallel DNA triplexes with a regulatory element of the KRAS proto-oncogene: A new class of antigene molecules overcoming potassium problem in triplex formation
-
Submitted
-
Paramasivam,M., Cogoi,S., Filichev,V., Bomholt,N., Pederesen,E.B. and Xodo,L.E. (2007) Erik B. Design of twisted intercalating nucleic acids (TINA) forming antiparallel DNA triplexes with a regulatory element of the KRAS proto-oncogene: A new class of antigene molecules overcoming potassium problem in triplex formation. Submitted.
-
(2007)
-
-
Paramasivam, M.1
Cogoi, S.2
Filichev, V.3
Bomholt, N.4
Pederesen, E.B.5
Xodo, L.E.6
|