Mosaic inactivation of the serum response factor gene in the myocardium induces focal lesions and heart failure

European Journal of Heart Failure

Volumn 10, Issue 7, 2008, Pages 635-645

  Gary Bobo, Guillaume ^a,b   Parlakian, Ara ^a,b   Escoubet, Brigitte ^c,d,e   Franco, Claudio Areias ^a,b   Clément, Sophie ^f   Bruneval, Patrick ^g   Tuil, David ^c   Daegelen, Dominique ^c   Paulin, Denise ^a,b   Li, Zhenlin ^a,b   Mericskay, Mathias ^a,b  

^a SORBONNE UNIVERSITÉ   (France)

^b CNRS   (France)

^c UNIVERSITÉ PARIS DESCARTES   (France)

^d BICHAT HOSPITAL   (France)

^e INSERM   (France)

^f UNIVERSITY OF GENEVA   (Switzerland)

^g HÔPITAL EUROPÉEN GEORGES POMPIDOU   (France)

Author keywords

Actin; Eccentric and concentric hypertrophy; Mosaic Cre recombination; Myocardial injury; Regional ventricular dysfunction

Indexed keywords

ACTIN; ALPHA ACTIN; CONTRACTILE PROTEIN; CRE RECOMBINASE; CYTOSKELETON PROTEIN; DESMIN; SERUM RESPONSE FACTOR;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ECHOCARDIOGRAPHY; GENE INACTIVATION; HEART FAILURE; HEART MUSCLE; HEART MUSCLE CELL; HEART MUSCLE INJURY; HEART VENTRICLE FUNCTION; HYPERTROPHIC CARDIOMYOPATHY; MOSAICISM; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSGENIC MOUSE; WILD TYPE;

ALLELES; ANALYSIS OF VARIANCE; ANIMALS; CARDIOMYOPATHY, HYPERTROPHIC; HEART FAILURE; IN SITU NICK-END LABELING; MICE; MICE, TRANSGENIC; MOSAICISM; MYOCARDIUM; MYOCYTES, CARDIAC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SERUM RESPONSE FACTOR;

EID: 46349085560     PISSN: 13889842     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejheart.2008.04.014     Document Type: Article

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